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Sodium dichloroacetate offered by PureDCA.com has more than 99% purity. We make it using a sophisticated synthesis process. No organic solvents are used during the production. We are currently the only providers of sodium dichloroacetate, which is equivalent in quality to NaDCA used in Medicor Cancer Centres. We ship internationally, with no exceptions. We are the only source of sodium dichloroacetate, which attaches a chemical analysis to every shipment, free of charge. The only place you can order our sodium dichloroacetate is the Cancer Virtual Community Store - Buy Sodium Dichloroacetate.

Welcome to Pharma-DCA.com the number 1 source to buy pharmaceutical quality DCA sodium dichloroacetate made only from pure crystal clear 99+% dichloroacetic acid There are no organic solvents used in making Pharma-DCA.com sodium dichloroacetate which comes as an excellent dry white powder.

f you are looking for Sodium Dichloroacetate or Miracle Mineral Supplement kit, then you are at the right place. We ship worldwide, also to the United States. We offer on-demand chemical compounds meeting the highest quality and safety standards. We support secure payment and 24 hours order processing as well as retail and bulk orders. Each batch comes with an individual chemical analysi

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Michelakis ED, Webster L, Mackey JR. Br J Cancer. 2008 Oct 7;99(7):989-94. Epub 2008 Sep 2. Review. PMID: 18766181 doi:10.1038/sj.bjc.6604554 The unique metabolism of most solid tumours (aerobic glycolysis, i.e., Warburg effect) is not only the basis of diagnosing cancer with metabolic imaging but might also be associated with the resistance to apoptosis that characterises cancer. The glycolytic phenotype in cancer appears to be the common denominator of diverse molecular abnormalities in cancer and may be associated with a (potentially reversible) suppression of mitochondrial function. The generic drug dichloroacetate is an orally available small molecule that, by inhibiting the pyruvate dehydrogenase kinase, increases the flux of pyruvate into the mitochondria, promoting glucose oxidation over glycolysis. This reverses the suppressed mitochondrial apoptosis in cancer and results in suppression of tumour growth in vitro and in vivo. Here, we review the scientific and clinical rationale supporting the rapid translation of this promising metabolic modulator in early-phase cancer clinical trials More than 40 nonrandomised trials of DCA in small cohorts of patients have been reported, but the first two randomised control trials of chronic oral therapy with DCA in congenital mitochondrial diseases were reported in 2006. In the first, a blinded placebo-controlled study was performed with oral DCA administered at 25 mg kg-1 day-1 in 30 patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) (Kaufmann et al, 2006). Most patients enrolled in the DCA arm developed symptomatic peripheral neuropathy, compared with 4 out of 15 in the placebo arm, leading to the termination of the study. Seventeen out of 19 patients had at least partial resolution of peripheral neurological symptoms by 9 months after discontinuation of DCA. This neurotoxicity res

sodium dichloroacetate

...has been the number one Google search term leading people to the blog this week - and that worries me. As I wrote about a week ago, dichloroacetate, or DCA, is the molecule tested recently by a team at University of Alberta for its ability to slow the growth of human lung cancer in immunocompromised rats. Among DCA's action is the ability to prevent cancer cells from producing lactic acid via aerobic glycolysis, a process used by more than half (but not all) tumors. Scientists continue to debate whether this process is a cause of cancer, or just a byproduct of malignant cell transformation. I am deeply concerned that desperate cancer patients may be trying to purchase dichloroacetate (DCA) and self-treat for cancer based on this highly-hyped single paper. To the credit of the researchers and their institution, who have set up a website to address the intense interest, they discourage such practice:

30 April,2007: Terminally ill patients with incurable cancers are increasingly using a compound via Internet trade that is not yet approved, reports Nature. The 'drug' in question -- dichloroacetate (DCA) - has been but found shrinking tumours in rats but yet to put on studies to ascertain its safety in human use.

Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation. Cao W, Yacoub S, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek C, Rosser CJ. Prostate. 2008 Aug 1;68(11):1223-31. PMID: 18465755 DOI: 10.1002/pros.20788

Dichloroacetate induces apoptosis in endometrial cancer cells. Wong JY, Huggins GS, Debidda M, Munshi NC, De Vivo I. Gynecol Oncol. 2008 Jun;109(3):394-402. Epub 2008 Apr 18. PMID: 18423823 doi:10.1016/j.ygyno.2008.01.038

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer.\nMichelakis ED, Webster L, Mackey JR.\nBr J Cancer. 2008 Oct 7;99(7):989-94. Epub 2008 Sep 2. Review.\nPMID: 18766181 \ndoi:10.1038/sj.bjc.6604554 \n

Dichloroacetate (DCA), a drug that has been used for many years in patients with metabolic disorders, has recently been gaining attention for its cancer-fighting capabilities. Studies in the lab have already shown its potential against lung, breast and glioblastoma cancer cells. Now a new study in the journal Gynecoogic Oncology finds that DCA might also be a promising therapy for endometrial cancer.

DCA, or dichloroacetic acid - New Scientist

After the news story in the Belgium press of two terminally ill cancer patients who used DCA and are now on the road to recovery, the Belgium people are asking questions. "It has brought a lot commotion in Belgium. All the people are wondering why they haven't heard from DCA any sooner! And they wonder why it isn't recognized yet as an official medicine for cancer!

The leader in DCA, BuyDCA.com makes the purest and lowest priced DCA available. BuyDCA.com's Sodium Dichloroacetate (DCA) is 99+% pure and is made with our patent-pending synthesis process. There are no organic solvents used in making

It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their "immortality". The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be

Dichloroacetate (DCA) Promising for Endometrial Cancer DCA virtually disappeared from the news about a year ago when it was forced off the open market by the FDA and all research into its efficacy as a cancer therapeutic had to go through officially sanctioned channels. I've kept track of it all this time through Google Email Alerts. This is the first bit of news on it in relation to cancer in a long time.

www.freeDCA.com is a scam A new scam site has popped up. www.freeDCA.com. This site has all the hallmarks of the previous scammer, who remains at large. Whether it is him or another person, this one is a fake.

Simultaneously Blocking Glycolysis and Fat Metabolism Can the use of DCA and a fatty acid metabolism blocker together force more cancer cells into using aerobic metabolism? Tim McGough used green tea extract, which contains EGCG, in his fantastic response. DCA works by reactivating mitochondria and shifts metabolism from glycolysis to glucose oxidation. Hopefully the cancer cell will then undergo apoptosis. However, cancer cells have an alternate energy source: fat metabolism. This page explores to possibility of blocking fat metabolism to help force the cell into apoptosis. Oral squamous cell carcinoma is a cancer that does not respond well to DCA. This study, Head and Neck Cancer Cell Lines Are Resistant to Mitochondrial-Depolarization-Induced Apoptosis states: "Results: ΔΨm in head and neck cell lines started to show slight loss of ΔΨm, while HL-60 showed significant loss of ΔΨm after 30 min of treatment. All cell lines demonstrated complete mitochondrial depolarization within 24 h, however, only the control cell line HL-60 underwent apoptosis. In addition, HNSCC cell lines did not demonstrate cytoplasmic cytochrome c release despite significant mitochondrial membrane depolarization, while HL-60 cell initiated apoptosis and cytochcrome c release after 24 h of treatment. Conclusions: Head and neck cancer cell lines exhibit defects in mitochondrial-membrane-depolarization-induced apoptosis as well as impaired release of cytochrome c despite significant mitochondrial membrane depolarization. Proximal defects in the mitochondrial apoptosis pathway are a feature of HNSCC.(head and neck squamous cell carcinoma)" Note that although the cell lines were depolarized, apoptosis did not occur. So I checked to see if fatty acid metabolism is used by squamous cell carcinoma.

Sodium dichloroacetate, 97% Item#:B21827