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Matti Narkia

MedWire News - Prostate Cancer - No link between steroid hormones and prostate cancer G... - 0 views

www.medwire-news.md/...tate_cancer_Gleason_score.html

2009 february news prostate cancer prostate_cancer steroid_hormones steroid hormones testosterone Gleason score Gleason_score estradiol

shared by Matti Narkia on 24 Feb 09 - Cached
  • “Whether this discrepancy was simply a results of different populations of men in these studies or, more likely, the absence of a consistent biologic relationship, our results suggest that steroid hormones are not a powerful driver of higher grade disease.”
  • Matti Narkia on 24 Feb 09
     
    MedWire News: Among patients with newly diagnosed prostate cancer, there is no link between circulating steroid hormone levels and Gleason score, conclude US investigators.
Matti Narkia

Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3)... - 0 views

www.springerlink.com/...fulltext.html

2008 February study research in_vitro sphingolipids apoptosis prostate cancer prostate_cancer PCa ceramide sphingomyelin PC-3 cells nutrition medline

shared by Matti Narkia on 21 Mar 09 - Cached
  • Matti Narkia on 21 Mar 09
     
    Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3) prostate cancer cells. Kent KD, Clubbs EA, Harper WJ, Bomser JA. Lipids. 2008 Feb;43(2):143-9. Epub 2008 Jan 10. PMID: 18188632 DOI: 10.1007/s11745-007-3148-
Matti Narkia

Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC)... - 0 views

www.sciencedirect.com/science

2005 April study clinical_trial rct humans prostate cancer prostate_cancer pca ellagic_acid chemotherapy Estramustine_phosphate Vinorelbine neutropenia nutrition medline supplementation supplements

shared by Matti Narkia on 09 Mar 09 - Cached
  • Matti Narkia on 09 Mar 09
     
    Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Eur Urol. 2005 Apr;47(4):449-54; discussion 454-5. Epub 2005 Jan 19. PMID: 15774240 doi:10.1016/j.eururo.2004.12.001
Matti Narkia

Folic Acid Supplements Linked To Higher Risk Of Prostate Cancer, Study Shows - 0 views

www.sciencedaily.com/...090310161436.htm

2009 March sciencedaily news folic acid folic_acid supplemental supplementation supplements prostate cancer prostate cancer prostate_cancer PCa risk nutrition folate

shared by Matti Narkia on 11 Mar 09 - Cached
  • Matti Narkia on 11 Mar 09
     
    ScienceDaily (Mar. 10, 2009) - A study led by researchers at the University of Southern California (USC) found that men who took a daily folic acid supplement of 1 mg daily had more than twice the risk of prostate cancer compared with men who took a placebo.
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits...[Nutr Cancer. 2008] - PubMed Result - 0 views

www.ncbi.nlm.nih.gov/...19005974

2008 study in_vitro in_vivo animal_study mice white button mushrooms white_button mushroom white_button_mushroom extract cancer prevention cancer_prevention prostate_cancer prostate pca nutrition medline apoptosis anticancer CLA conjugated_linoleic_acid

shared by Matti Narkia on 10 Mar 09 - No Cached
  • Matti Narkia on 10 Mar 09
     
    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. PMID: 19005974
Matti Narkia

New Lab Evidence Suggests Preventive Effect Of Herbal Supplement In Prostate Cancer - 0 views

www.sciencedaily.com/...090212093646.htm

2009 February sciencedaily news prostate cancer prostate cancer prostate_cancer PCa red clover red clover red_clover isoflavones Trifolium pretense Trifolium_pretense herb herbs herbal_medicine cam

shared by Matti Narkia on 22 Feb 09 - Cached
  • Matti Narkia on 22 Feb 09
     
    When these cell cultures were treated with red clover isoflavones, the androgenic effects of DHEA were reversed. "Something is happening in the prostate tissue microenvironment that is illustrating a potential cancer prevention effect from this supplement," said Arnold. Red clover isoflavones may modify androgenic effects in the prostate but much more work in the laboratory and clinic is needed to validate these effects.
Matti Narkia

MedWire News - Oncology - Serum 25(OH)D levels linked to prostate cancer prognosis - 0 views

www.medwire-news.md/...prostate_cancer_prognosis.html

2009 February news vitamin_D vitamin D calcidiol 25ohd 25(OH)D prostate cancer prostate_cancer prostate cancer prognosis disease_progression progression mortality

shared by Matti Narkia on 22 Feb 09 - Cached
  • The researchers conclude: “This study shows a strong association between 25(OH)D levels and cause-specific mortality in patients with prostate cancer. The strength of the association indicates that prostate cancer patients can benefit from increasing the level of serum 25(OH)D if it is below 50 nmol/l.”
  • Matti Narkia on 22 Feb 09
     
    MedWire News: Serum levels of 25-hydroxy vitamin D (25(OH)D) play a role in prostate cancer disease progression and are a potential prognostic indicator, Norwegian study findings suggest.
Matti Narkia

Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in h... - 0 views

www.ncbi.nlm.nih.gov/...query.fcgi

Silibinin mitoxantrone inhibit growth apoptosis prostate cancer PCa silymarin milkthistle herbs herbal herbalmedicine medicinal medicine medline peer-reviewed science study research 2007 imported delicious prostate_cancer

shared by Matti Narkia on 24 Feb 09 - No Cached
  • Matti Narkia on 24 Feb 09
     
    Flaig TW, Su LJ, Harrison G, Agarwal R, Glode LM. Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells. Int J Cancer. 2007 Jan 17; [Epub ahead of print] PMID: 17230508 [PubMed - as supplied
Matti Narkia

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. -... - 0 views

www.ncbi.nlm.nih.gov/...query.fcgi

silybin-phytosome prostate cancer silibinin silymarin silybin milkthistle herbs herbal herbalmedicine medicine medline medicinal pca peer-reviewed science study research pubmed prevention treatment imported delicious prostate_cancer

shared by Matti Narkia on 24 Feb 09 - No Cached
  • Matti Narkia on 24 Feb 09
     
    Flaig TW, Gustafson DL, Su LJ, Zirrolli JA, Crighton F, Harrison GS, Pierson AS, Agarwal R, Glode LM. A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. Invest New Drugs. 2007 Apr;25(2):139-46. Epub 2006 Nov 1. PMID
Matti Narkia

Prostate cancer chemoprevention by silibinin: bench to bedside. - Entrez PubMed - 0 views

www.ncbi.nlm.nih.gov/...query.fcgi

Prostate cancer chemoprevention silibinin 2006 silybin silymarin milkthistle herbal herbalmedicine herbs pca prevention medicine medline medicinal science study peer-reviewed pubmed research imported delicious prostate_cancer

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    Singh RP, Agarwal R. Prostate cancer chemoprevention by silibinin: bench to bedside. Mol Carcinog. 2006 Jun;45(6):436-42. Review. PMID: 16637061 [PubMed - indexed for MEDLINE]
Matti Narkia

Prostate cancer prevention by silibinin. - Entrez PubMed - 0 views

www.ncbi.nlm.nih.gov/...query.fcgi

Prostate cancer prevention silibinin herbs herbalmedicine herbal medicine medicinal medline pca milkthistle silybin silymarin pubmed peer-reviewed science study research imported delicious prostate_cancer

shared by Matti Narkia on 24 Feb 09 - No Cached
  • Matti Narkia on 24 Feb 09
     
    Singh RP, Agarwal R. Prostate cancer prevention by silibinin. Curr Cancer Drug Targets. 2004 Feb;4(1):1-11. Review. PMID: 14965263 [PubMed - indexed for MEDLINE]
Matti Narkia

Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induc... - 0 views

www.ncbi.nlm.nih.gov/...query.fcgi

Zyflamend herbal COX inhibitor apoptosis prostate cancer COX-2 expression COX-1 herbs herbalmedicine anti-inflammatory antiinflammatory medicine medicinal medline pca peer-reviewed science study research pubmed imported delicious prostate_cancer

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    Bemis DL, Capodice JL, Anastasiadis AG, Katz AE, Buttyan R. Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression. Nutr Cancer. 2005;52(2):202-12. PMID:
Matti Narkia

ScienceDaily: Vitamin D Inhibits Progression Of Some Prostate Cancers - 0 views

www.sciencedaily.com/...060208163311.htm

2006 February vitamins cancer prostate news medical supplements supplementation nutrition sun sunshine vitamin D vitamin_D prostate_cancer pca

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    ScienceDaily (Feb. 8, 2006) - Vitamin D can inhibit the spread of prostate cancer cells by limiting the activity of two specific enzymes, University of Rochester Medical Center scientists report. \n\nThe finding means that vitamin D could provide beneficial treatment to prostate cancer patients with high levels of the enzymes, the scientists said.\n
Matti Narkia

Vitamin D may inhibit prostate cancer growth - mechanism reported - 0 views

www.nutraingredients.com/...ng.asp

2006 february news prostate cancer prostate_cancer PCa vitamin_D vitamin D growth-inhibitory mechanism mechanisms

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    The in vitro study, reported in the journal Carcinogenesis (Vol. 27, pp. 32-42), showed that vitamin D, in the form of the highly active 1alpha, 25-dihydroxyvitamin D3 (1,25-VD), inhibited the function of protease enzymes that are involved in tumour invasion. "We found that 1,25-VD decreased matric metalloproteinases (MMP-9) and cathepsins (CPs), while it [also] increased the activity of their counterparts, tissue inhibitors of metalloproteinase-1 (TIMP-1) and cathepsin inhibitors," wrote lead author Bo-Ying Bao from the University of Rochester and Taipei Medical University. "Mechanistic studies showed that 1,25-VD did not suppress MMP-9 expression at the transcriptional level, but reduced its mRNA stability," said Bao.
Matti Narkia

Differential effects of selenium on benign and malignant prostate epithelial cells: sti... - 0 views

www.ncbi.nlm.nih.gov/...19235042

2009 February study research in_vitro prostate cancer prostate_cancer PCa selenium sodium selenite sodium_selenite nutrition medline cells benign malignant LNCaP PC-3 androgen-sensitive androgen-independent

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Kandaş NO, Randolph C, Bosland MC. Nutr Cancer. 2009;61(2):251-64. PMID: 19235042
Matti Narkia

Older Men Urged to Consider a Drug to Prevent Prostate Cancer - NYTimes.com - 0 views

www.nytimes.com/...25prostate.html

2009 February news NYT NYTimes older old elderly men prostate cancer prostate cancer prostate_cancer prevention cancer_prevention drug finasteride risk risk_reduction reduction PCa

shared by Matti Narkia on 26 Feb 09 - Cached
  • Matti Narkia on 26 Feb 09
     
    For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.
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