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Matti Narkia

Marijuana Compounds Could Beat Back Brain Cancer - Cancer Information (Cancers, Symptom... - 2 views

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    By Randy Dotinga
    HealthDay Reporter

    MONDAY, Jan. 11 (HealthDay News) -- Preliminary research suggests that a combination of compounds in marijuana could help fight off a particularly deadly form of brain cancer.

    But the findings shouldn't send patients rushing to buy pot: the levels used in the research appear to be too high to obtain through smoking. And there's no sign yet that the approach works in laboratory animals, let alone people.
Matti Narkia

Mango effective in preventing, stopping certain colon, breast cancer cells - 0 views

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    "COLLEGE STATION - Mango. If you know little about this fruit, understand this: It's been found to prevent or stop certain colon and breast cancer cells in the lab.

    That's according to a new study by Texas AgriLife Research food scientists, who examined the five varieties most common in the U.S.: Kent, Francine, Ataulfo, Tommy/Atkins and Haden.

    Though the mango is an ancient fruit heavily consumed in many parts of the world, little has been known about its health aspects. The National Mango Board commissioned a variety of studies with several U.S. researchers to help determine its nutritional value.

    "If you look at what people currently perceive as a superfood, people think of high antioxidant capacity, and mango is not quite there," said Dr. Susanne Talcott, who with her husband, Dr. Steve Talcott, conducted the study on cancer cells. "In comparison with antioxidants in blueberry, acai and pomegranate, it's not even close."

    But the team checked mango against cancer cells anyway, and found it prevented or stopped cancer growth in certain breast and colon cell lines, Susanne Talcott noted.

    "It has about four to five times less antioxidant capacity than an average wine grape, and it still holds up fairly well in anticancer activity. If you look at it from the physiological and nutritional standpoint, taking everything together, it would be a high-ranking super food," she said. "It would be good to include mangoes as part of the regular diet."

    The Talcotts tested mango polyphenol extracts in vitro on colon, breast, lung, leukemia and prostate cancers. Polyphenols are natural substances in plants and are associated with a variety of compounds known to promote good health."
Matti Narkia

Review Article: Vitamin D Acquisition and Breast Cancer Risk -- Pérez-López e... - 0 views

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    Review article: vitamin D acquisition and breast cancer risk.
    Pérez-López FR, Chedraui P, Haya J.
    Reprod Sci. 2009 Jan;16(1):7-19. Review.
    PMID: 19144887
    DOI: 10.1177/1933719108327595

    Conclusions: Although there are controversial results, it seems plausible that sufficient endogenous vitamin D levels may have a protective function on mammary cells, reducing breast cancer risk.
Matti Narkia

Millions of Needless Deaths - Life Extension - 0 views

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    A large number of new vitamin D studies have appeared in the scientific literature since I wrote my plea to the federal government. These studies don't just confirm what we knew 16 months ago-they show that optimizing vitamin D intake will save even more lives than what we projected.
    Vitamin D More Effective Than Previously Known

    For instance, a study published in June 2008 showed that men with low vitamin D levels suffer 2.42 times more heart attacks. Now look what this means in actual body counts.
Matti Narkia

How spicy foods can kill cancers - BBC NEWS | Health - 0 views

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    Scientists have discovered the key to the ability of spicy foods to kill cancer cells.
    They found capsaicin, an ingredient of jalapeno peppers, triggers cancer cell death by attacking mitochondria - the cells' energy-generating boiler rooms.
Matti Narkia

Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and... - 0 views

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    Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial.
    Gogos CA, Ginopoulos P, Salsa B, Apostolidou E, Zoumbos NC, Kalfarentzos F.
    Cancer. 1998 Jan 15;82(2):395-402.
    PMID: 9445198
Matti Narkia

A platelet cloak for tumor cells - Blood, January 1, 2005 - 0 views

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    H. Weiler
    A platelet cloak for tumor cells
    Blood, January 1, 2005; 105(1): 5 - 6.

    Palumbo and colleagues show that platelets and fibrinogen protect metastatic tumor cells from elimination by NK cells, confirming a striking mechanistic link between activation of the blood coagulation system and the spread of tumor metastases
Matti Narkia

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cel... - 0 views

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    Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.
    Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Jirousková M, Degen JL.
    Blood. 2005 Jan 1;105(1):178-85. Epub 2004 Sep 14.
    PMID: 15367435
    DOI 10.1182/blood-2004-06-2272
Matti Narkia

Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell. - [Med... - 0 views

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    Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell.
    Wang JS, Chung Y, Chow SE.
    Med Sci Sports Exerc. 2009 Jan;41(1):115-22.
    PMID: 19092699
Matti Narkia

Active Hexose Correlated Compound shown to enhances immune system by increasing product... - 0 views

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    A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs).

    DCs are a key part of the immune system responsible for presenting foreign substances to other immune system cells.

    The study was conducted in a double-blind randomized fashion where twenty-one healthy subjects received a placebo or AHCC at 3.0 g/day for 4 weeks. Blood samples were obtained and measured at baseline and at 4 weeks. The number of circulating types of DCs was measured which included CD 11c+ DCs (myeloid DC population; DC1) and CD11c- DCs (lymphoid DC population; DC2). Other parameters measured included mixed-leukocyte reaction (MLR), natural killer (NK) cell activity, the proliferative response of T lymphocytes toward mitogen (phytohemagglutinin [PHA]) and cytokine production of interleukin (IL)-2, IL-4, IL-6, IL-10, interferon gamma-gamma, and (alpha)-tumor necrosis factor.
Matti Narkia

Controversy: Fighting cancer with oncolytic viruses - 0 views

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    Fighting cancer with oncolytic viruses.
    Chernajovsky Y, Layward L, Lemoine N.
    BMJ. 2006 Jan 21;332(7534):170-2. Review. .
    PMID: 16424499

Matti Narkia

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid r... - 0 views

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    Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.
    Casanova ML, Blázquez C, Martínez-Palacio J, Villanueva C, Fernández-Aceñero MJ, Huffman JW, Jorcano JL, Guzmán M.
    J Clin Invest. 2003 Jan;111(1):43-50.
    PMID: 12511587
    doi:10.1172/JCI16116
Matti Narkia

Ursolic Acid: Excitement in Allergy, Inflammation, and Cancer Management - 0 views

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    Ursolic acid is a component of many herbs that seems to have a protective effect versus inflammation and its various ramifications
Matti Narkia

Cannabinoids and cancer: causation, remediation, and palliation : The Lancet Oncology - 0 views

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    Cannabinoids and cancer: causation, remediation, and palliation.
    Hall W, Christie M, Currow D.
    Lancet Oncol. 2005 Jan;6(1):35-42. Review.
    PMID: 15629274
    doi:10.1016/S1470-2045(04)01711-5
Matti Narkia

Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mende... - 0 views

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    Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach.
    Boccia S, Hashibe M, Gallì P, De Feo E, Asakage T, Hashimoto T, Hiraki A, Katoh T, Nomura T, Yokoyama A, van Duijn CM, Ricciardi G, Boffetta P.
    Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):248-54.
    PMID: 19124505
    doi: 10.1158/1055-9965.EPI-08-0462
Matti Narkia

Technology Review: Implant Makes Cells Kill Cancer - 0 views

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    A new approach to cancer treatment called immunotherapy could spare patients at least some of the grueling battery of chemotherapy treatments by retraining the body's own defenders--the cells of the immune system--to recognize and destroy tumors. Now researchers at Harvard University have developed a simple way to do this inside the body: a polymer implant attracts and trains immune-system cells to go after cancer.

    The experimental approach has shown great success in animal studies, increasing the survival rate of mice with a deadly melanoma from 0 to 90 percent. The implant could also be used to treat diseases of the immune system such as arthritis and diabetes, and, potentially, to train other kinds of cells, including stem cells used to repair damage to the body.
Matti Narkia

A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes A... - 0 views

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    A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
    Bonnet S, Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, Lee CT, Lopaschuk GD, Puttagunta L, Bonnet S, Harry G, Hashimoto K, Porter CJ, Andrade MA, Thebaud B, Michelakis ED.
    Cancer Cell. 2007 Jan;11(1):37-51.
    PMID: 17222789
    doi:10.1016/j.ccr.2006.10.020
Matti Narkia

DCA, Dichloroacetate for Cancer - Dr. Weil - 0 views

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    DCA is an organic compound, and a byproduct of TCE (trichloroethylene), a chemical that has been a concern in the development of cancer. In January 2007, researchers at the University of Alberta published a study in the journal Cancer Cell suggesting that DCA showed promise in shrinking tumors in lab rats as well as inhibiting growth of cultured human cancer cells. They hypothesized that DCA may be able to change cancer cells back to normal ones by switching them from the aberrant energy pathways they rely on to those used by normal cells.
Matti Narkia

Addressing the health benefits and risks, involving vitamin D or skin cancer, of increa... - 0 views

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    Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure.\nMoan J, Porojnicu AC, Dahlback A, Setlow RB.\nProc Natl Acad Sci U S A. 2008 Jan 15;105(2):668-73. Epub 2008 Jan 7.\nPMID: 18180454
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