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Matti Narkia

Mango effective in preventing, stopping certain colon, breast cancer cells - 0 views

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    "COLLEGE STATION - Mango. If you know little about this fruit, understand this: It's been found to prevent or stop certain colon and breast cancer cells in the lab.

    That's according to a new study by Texas AgriLife Research food scientists, who examined the five varieties most common in the U.S.: Kent, Francine, Ataulfo, Tommy/Atkins and Haden.

    Though the mango is an ancient fruit heavily consumed in many parts of the world, little has been known about its health aspects. The National Mango Board commissioned a variety of studies with several U.S. researchers to help determine its nutritional value.

    "If you look at what people currently perceive as a superfood, people think of high antioxidant capacity, and mango is not quite there," said Dr. Susanne Talcott, who with her husband, Dr. Steve Talcott, conducted the study on cancer cells. "In comparison with antioxidants in blueberry, acai and pomegranate, it's not even close."

    But the team checked mango against cancer cells anyway, and found it prevented or stopped cancer growth in certain breast and colon cell lines, Susanne Talcott noted.

    "It has about four to five times less antioxidant capacity than an average wine grape, and it still holds up fairly well in anticancer activity. If you look at it from the physiological and nutritional standpoint, taking everything together, it would be a high-ranking super food," she said. "It would be good to include mangoes as part of the regular diet."

    The Talcotts tested mango polyphenol extracts in vitro on colon, breast, lung, leukemia and prostate cancers. Polyphenols are natural substances in plants and are associated with a variety of compounds known to promote good health."
Matti Narkia

Anticancer Properties of Ganoderma Lucidum Methanol Extracts In Vitro and In Vivo - Nut... - 0 views

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    Anticancer properties of Ganoderma lucidum methanol extracts in vitro and in vivo.
    Harhaji Trajković LM, Mijatović SA, Maksimović-Ivanić DD, Stojanović ID, Momcilović MB, Tufegdzić SJ, Maksimović VM, Marjanović ZS, Stosić-Grujicić SD.
    Nutr Cancer. 2009;61(5):696-707.
    PMID: 19838944
    DOI: 10.1080/01635580902898743

    Anticancer activities of various extracts of the medicinal mushroom, Ganoderma lucidum, have been widely demonstrated and are mainly associated with the presence of different bioactive polysaccharides and triterpenoids. We have evaluated and compared in vitro and in vivo the antitumor effects of two preparations from Ganoderma lucidum: a methanol extract containing total terpenoids (GLme) and a purified methanol extract containing mainly acidic terpenoids (GLpme). Both extracts inhibited tumor growth of B16 mouse melanoma cells inoculated subcutaneously into syngeneic C57BL/6 mice and reduced viability of B16 cells in vitro, whereby GLme exhibited stronger effect. Furthermore, anticancer activity of GLme was demonstrated for the first time against two other rodent tumor cell lines, L929-mouse fibrosarcoma and C6-rat astrocytoma. The mechanism of antitumor activity of GLme comprised inhibition of cell proliferation and induction of caspase-dependent apoptotic cell death mediated by upregulated p53 and inhibited Bcl-2 expression. Moreover, the antitumor effect of the GLme was associated with intensified production of reactive oxygen species, whereas their neutralization by the antioxidant, N-acetyl cysteine, resulted in partial recovery of cell viability. Thus, our results suggest that GLme might be a good candidate for treatment of diverse forms of cancers.
Matti Narkia

Coriolus versicolor extracts: relevance in cancer management (free full text PDF availa... - 0 views

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    Coriolus versicolor extracts: relevance in cancer management
    M. Szeto, BSC RD
    Curr Oncol. 2008 April; 15(2): 79.
Matti Narkia

New data on link between cancer and nutrition discussed at European symposium - 0 views

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    European experts in cancer and nutrition are meeting in Zurich, Switzerland late this month to discuss cutting-edge research in one of the most important and fiercely debated topics in cancer prevention: the link between diet and cancer.

    There is growing evidence that many cancers may be prevented through healthy lifestyle, including a nutritionally balanced diet. In addition, nutritional problems can also have a negative impact on cancer management and the lives of patients.

    Other presentations will include new data on topics such as:

    Childhood nutrition and later breast cancer risk
    The anti-tumour effects of green tea
    Malnutrition and patient distress in cancer
    Possible anti-tumour effects of soy extracts in mice
    Estrogens in beef and cancer risk

Matti Narkia

Structure-function relationships of anthocyanins from various anthocyanin-rich extracts... - 0 views

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    Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth.
    Jing P, Bomser JA, Schwartz SJ, He J, Magnuson BA, Giusti MM.
    J Agric Food Chem. 2008 Oct 22;56(20):9391-8. Epub 2008 Sep 19.
    PMID: 18800807
    DOI: 10.1021/jf8005917
Matti Narkia

Drugs From Vegetables May Target Melanoma Tumors - Cancer Information (Cancers, Symptom... - 0 views

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    THURSDAY, March 5 (HealthDay News) -- A drug based on compounds extracted from cruciferous vegetables such as broccoli and cabbage could offer a potent and safe treatment against melanoma, Penn State College of Medicine researchers say.
Matti Narkia

Blueberries may reduce childhood cancer risk: Study - 0 views

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    Extracts from blueberries may reduce the size of tumours primarily found in infants and children, and improve survival, suggest new findings from a study with mice.
    According to new results from the Ohio State University, mice fed the blueberry extract doubled their lifespan, and had tumours 60 per cent smaller that in control mice.
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