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Liz Richardson

Phyto-oestrogens: where are we now? - 0 views

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    What is known about phytoestrogens? How does it affect us? What can be done to improve the public knowledge concerning phytoestrogen intake? Do they interact with other nutritional factors?
Vanessa Ward

San Francisco Medical Society | The Weight of Evidence - 0 views

  • “leading to neglect of other plausible mechanisms and well-intentioned but potentially ill-founded proposals for reducing obesity rates”
  • Since publication of that review, substantial evidence has emerged that increases the plausibility of one of the alternative mechanisms suggested by Keith et al: disruption of weight regulation by endocrine-disrupting chemicals (EDCs) in the environment.
  • Concerns about the potential contribution of EDCs to childhood obesity build from two considerations, one out of human biology and the other from animal experiments
  • ...7 more annotations...
  • Prior
  • toxicologists were concerned more with weight loss, which was seen as an adverse outcome.
  • Many of these chemicals alter the behavior of specific genes that are involved in determining the number of fat cells (adipocytes) an individual will have as an adult.
  • he list of contaminants implicated by animal studies is substantial, including several estrogenic EDCs such as DES, bisphenol A, soy phytoestrogens
  • Almost no human data are available to test the obesogen hypothesis in people. No epidemiological evidence exists, because the hypothesis is so new
  • One in vitro experiment, however, has demonstrated that exposure to obesogens increases the rate of conversion of human stem cells to adipocytes (Kirchner et al 2010), confirming the validity of the basic mechanism and the relevance of the animal studies to people.
  • That would be a big win for medicine and public health.
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    San Francisco Medical Society discusses the possible relationship between chemical exposure and the obesity epidemic.
Matthew Ragan

Open Science Directory - Home - 1 views

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    Access to scientific literature is very important for the scientific work in developing countries . As a result of different projects  a large collection of  e-journals is now available for researchers in developing countries. The number of Open Access Journals is growing steadily as we can see in the Directory of Open Access Journals. Major UNO organizations like WHO, FAO and UNEP have their specific programs for the scientific institutions in low-income countries. Finally a lot of universities, institutes and other organizations are supporting access programs. The most important are INASP, eIFL and eJDS.
Anna McLean

NRDC: Endocrine Disruptors - 0 views

shared by Anna McLean on 11 Jun 10 - Cached
  • 5. Should humans be concerned for their health based on evidence that fish, birds and alligators have been affected? Yes. All vertebrates (fish, amphibians, reptiles, birds, and mammals, including humans) are fundamentally similar during early embryonic development. Scientists can therefore use the evidence acquired on other species to make predictions about endocrine disrupting effects on humans.
  • 6. Is there direct evidence that humans are susceptible to endocrine disruption?
  • 8. These days don't chemicals have to be safe to be allowed on the market? No.
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    Frequently asked-type questions
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    Obviously, this site is for the general public. But, it could be a useful link for your webpages if you want some basic background information to persuade people that this IS relevant to them and their families.
suwhitte

Environmental Health Perspectives - 0 views

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    Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news published by the U.S. National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services. EHP's mission is to serve as a forum for the discussion of the interrelationships between the environment and human health by publishing in a balanced and objective manner the best peer-reviewed research and most current and credible news of the field. With an impact factor of 6.12, EHP is the top monthly journal in public, environmental, and occupational health and the second-ranked monthly journal in environmental sciences. The environmental health sciences include many fields of study and increasingly comprise a multidisciplinary research area. EHP publishes articles from a wide range of scientific disciplines encompassing basic research; epidemiologic studies; risk assessment; relevant ethical, legal, social, environmental justice, and policy topics; longitudinal human studies; in vitro and in vivo animal research with a clear relationship to human health; and environmental medicine case reports. Because children are uniquely sensitive to their environments, EHP devotes a research section specifically to issues surrounding children's environmental health. Search current issue and archives for journal articles related to your topic.
Liz Richardson

Global assessment of the state-of-the-science of endocrine disruptors - 0 views

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    This is just the index, but the WHO has attempted to pinpoint which hormone compounds are most effective EEDs, and which hormones are most often mimicked. Discusses EED effects on wildlife as well as humans. Criteria for assessment of endocrine disruptors proposed for future studies.
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