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Trevor F

Integration of the yeast retrovirus-like element Ty3 upstream of a human gene expressed... - 1 views

diigo.com/0sv8o

retrovirus-like Ty3 Saccharmyces cerevisae yeast genetic engineering

shared by Trevor F on 12 Sep 12 - No Cached
  • Trevor F on 12 Sep 12
     
    Components of viral machinery being used to modify the genome of an organism. Exciting stuff yes?
Matthew Marshall

Ebola outbreak kills 15 in eastern Congo - Yahoo! News - 1 views

news.yahoo.com/5-eastern-congo-170536276.html

Ebola Virus Outbreak

shared by Matthew Marshall on 11 Sep 12 - No Cached
  • Matthew Marshall on 11 Sep 12
     
    In my opinion, VHFs are among the scariest of viruses. Also, to the best of my knowledge, the reservoir AND vector for the virus have yet to be found. It just pops out of the jungle every so often, and then disappears back into it, Frightening...
mattgreatens

High Incidence of Multiple Viral Infections Identified in Upper Respiratory Tract Infec... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0044568

Upper Respiratory Tract Infections virology

shared by mattgreatens on 11 Sep 12 - No Cached
  • mattgreatens on 11 Sep 12
     
    Did not know that 80% of Upper Respiratory Tract Infections(URTI) are viral.
kchenvert09

Worst Year of the West Nile - 2 views

www.medicalnewstoday.com/...249974.php

virology Journals west nile

shared by kchenvert09 on 11 Sep 12 - No Cached
  • kchenvert09 on 11 Sep 12
     
    interesting that this is the worst year but I feel that it hasnt been mentioned nearly as much as it has the past couple years
rboreen

Improper Tagging of the Non-Essential Small Capsid Protein VP26 Impairs Nuclear Capsid ... - 3 views

www.plosone.org/...10.1371%2Fjournal.pone.0044177

virology herpes virus capsid protein

shared by rboreen on 10 Sep 12 - No Cached
    • Casey Finnerty
      Casey Finnerty on 10 Sep 12
       
      I'm often surprised at how often tagging a protein with another large protein works, i.e. does not interfere with the function of the tagged protein. Considering how complex the process of viral assembly is, I'm not surprised it would be sensitive to the location of the tag.
jiyoung yoon

Association of HIV Diversity and Survival in HIV-Infected Ugandan Infants - 10 views

www.plosone.org/...10.1371%2Fjournal.pone.0018642

hiv genetic disease virology

shared by jiyoung yoon on 09 Sep 12 - No Cached
    • Sarah Muncy
      Sarah Muncy on 10 Sep 12
       
      Ha, so again, like an organism. Where a population has a great deal of genetic diversity, there are more traits onto which natural selection can act. The more diverse the HIV is at this given stage means a failure in this case though, as the host dies and cannot transmit the disease. Strange.
  • Casey Finnerty on 10 Sep 12
     
    That's a really cool observation, Sarah! It's really all about transmission. Since HIV is (primarily) sexually transmitted, infection in infants (via transovarial transmission) may be considered a dead end for the virus. Perhaps vertical transmission is an aberrance. If HIV would evolve into a less virulent form, perhaps vertical transmission would become more important. Just sayin'...
sdahlseng10

Cigarette Smoke Modulates Expression of Human Rhinovirus-Induced Airway Epithelial Host... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0040762

rhinovirus cigarette smoking epithelium tissue culture

shared by sdahlseng10 on 10 Sep 12 - No Cached
  • sdahlseng10 on 10 Sep 12
     
    This is an interesting article about the gene products that are up-regulated by a rhinovirus infection of respiratory tract epithelial cells, and how that response is limited with the introduction of a cigarette smoke extract. Experiment carried out in human epithelial tissue culture and gene products measured with PCR and immunoblotting.
  • Casey Finnerty on 10 Sep 12
     
    Nice molecular evidence behind the observation that smokers get colds more often, don't you think?
Casey Finnerty

PLoS ONE: Fatal Cases of Influenza A in Childhood - 7 views

www.plosone.org/...10.1371%2Fjournal.pone.0007671

shared by Casey Finnerty on 10 Sep 12 - No Cached
  • This work presents a rare insight into fatal influenza H3N2 in healthy children.
    • Casey Finnerty
      Casey Finnerty on 10 Sep 12
       
      So I think we can see why some virologists were uncomfortable with keeping the swine barn open at the state fair this year!
  • Tyrell Varner on 10 Sep 12
     
    Vaccinations are nice, until an antigenic strain is formed. In which case it's back to the drawing board to create a new one as soon as possible. Influenza is constantly changing in order to thrive. Amazing!
Casey Finnerty

Expression Strategy of Densonucleosis Virus from the German Cockroach, Blattella germanica - 2 views

jvi.asm.org/...11855.long

virology

shared by Casey Finnerty on 07 Sep 12 - No Cached
  • Cell culture propagation and virus infection.For the propagation of BgDNV, a culture of B. germanica BGE-2 cells previously isolated from embryonic tissues was used (30).
Casey Finnerty

New tick-borne virus puts the bite on Missouri farmers - Vitals - 3 views

vitals.nbcnews.com/...s-the-bite-on-missouri-farmers

virology

shared by Casey Finnerty on 04 Sep 12 - No Cached
  • “This particular virus has never been detected before,” said Nicholson. “This is unique to the world.”So far, the Missouri men are the only known victims of the new germ, which has been identified as a phlebovirus, part of the Bunyaviridae family of potentially serious bugs. Hantavirus, spread by deer mice, comes from that group. So does the deadly Crimean-Congo hemorrhagic fever.
Casey Finnerty

PLoS Pathogens: Polydnaviruses as Symbionts and Gene Delivery Systems - 5 views

www.plospathogens.org/...10.1371%2Fjournal.ppat.1002757

virology

shared by Casey Finnerty on 29 Aug 12 - No Cached
  • Casey Finnerty on 29 Aug 12
     
    This paper describes the fascinating replication cycle of brachoviruses, which integrate their genomes (or portions of their genomes) into both wasp and caterpillar hosts, to benefit the parasitic wasp. In this role, these viruses function as endosymbionts, challenging the traditional view of all viruses as parasites.
  • Casey Finnerty on 30 Aug 12
     
    Please read this paper for the course. I don't plan to discuss it much more in the course, but there may be questions on this story on your exam.
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