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Casey Finnerty

Yeast Infection Led to Removal of Transplanted Uterus - The New York Times - 0 views

www.nytimes.com/...al-of-transplanted-uterus.html

shared by Casey Finnerty on 11 Apr 16 - No Cached
  • The infection was caused by a fungus, a type of yeast called Candida albicans
  • It is normally found in the vagina, living in balance with bacteria and other microbes. But illness or some medications can disrupt the balance, allowing for a problematic overgrowth of the yeasts.
  • The surgeons said that since yeasts normally inhabit the genital tract, they could have come from either the donor or the recipient.
  • ...11 more annotations...
  • But in transplant recipients, yeast infections can be hard to control, because the drugs that prevent rejection also prevent the immune system from fighting the infection. If a yeast infection spreads into the bloodstream, it can be extremely difficult to treat, and can be fatal.
  • Doctors rushed Ms. McFarland into surgery and discovered that an infection — they did not know then what kind — had extended into an artery they had connected to provide blood flow to the uterus. It had damaged the vessel and caused clots. The transplant had to be removed immediately. A week later, Ms. McFarland needed another operation, to treat more bleeding.
  • Once the cause of the infection was identified, she was treated with antifungal medicines. With the transplant removed, she was able to stop taking antirejection drugs and give her immune system a chance to recover and help control the infection.
  • She spent about five weeks in the hospital. Dr. Tzakis said she was still taking antifungal medicine, but was well.
  • The goal of the surgery is to make pregnancy and childbirth possible for women who were born without a uterus or lack one because of illness or injury.
  • They said they were considering various options, like using antifungal medicines preventively and washing the tissues of both the donor and recipient to reduce the risk of infection.
  • The only successful uterus transplants have been performed in Sweden, at the University of Gothenburg. Nine women have had the transplants there, and five have given birth.
  • Two of the nine transplants failed during the first year after the surgery and had to be removed
  • the other because of a bacterial infection.
  • Unlike the Cleveland team, doctors in Sweden used live uterus donors rather than cadavers for the transplants.
  • He also said that the Baylor team had adjusted its screening procedures to take into account possible exposure to the Zika virus
Megan Goldman

Starmerella bombicola influences the metabolism of Saccharomyces cerevisiae at pyruvate... - 0 views

www.ncbi.nlm.nih.gov/...PMC3295710

shared by Megan Goldman on 30 Apr 13 - No Cached
  • Megan Goldman on 30 Apr 13
     
    Read an article on a fermentation guru (http://www.nytimes.com/2012/09/19/dining/fermentation-guru-helps-chefs-find-new-flavors.html?pagewanted=2&ref=microbiology), so was interested in finding an article on fermentation and found this article on the fermentation of wine mixing species of yeasts and the benefits. The use of a multistarter fermentation process with S. cerevisiae and non-Saccharomyces wine yeasts has been proposed to simulate natural must fermentation and to confer greater complexity and specificity to wine. The advantage of this process is to simulate a spontaneous process avoiding the risks of stuck fermentation. Furthermore, non-Saccharomyces wine strains could have some specific enological characteristics that are absent in S. cerevisiae species, leading to combined, synergic and/or additive effects on the final wine.
Katelyn Madigan

Why sourdough bread resists mold - 1 views

www.sciencedaily.com/...130221194239.htm

resistance bread mold

shared by Katelyn Madigan on 22 Feb 13 - No Cached
  • sourdough bread differs from ordinary bread in having an extra fermentation step, over and above yeast fermentation. This step is mediated by lactic acid bacteria, typically of the genus Lactobacillus
  • L. hammesii produced substantial quantities of hydroxylated monounsaturated fatty acids
  • A second antifungal fatty acid produced by cereal enzymes
  • Casey Finnerty on 22 Feb 13
     
    Neat article on microbial competition, across kingdoms no less!
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