South Africa Halts Coronavirus Vaccine Rollout Because of New Variant - The New York Times - 0 views
-
The new findings from South Africa were far from conclusive: They came from a small clinical trial that enrolled fewer than 2,000 people. And they did not preclude what some scientists say is the likelihood that the vaccine protects against severe disease from the variant — a key indicator of whether the virus will overwhelm hospitals and kill people.
-
“It’s becoming increasingly apparent that we’re going to be stuck in this whack-a-mole reality, where we have variants that don’t respond to vaccines,” said Andrea Taylor, the assistant director at Duke Global Health Innovation Center. “We’ll try to tweak those vaccines to target new variants, but because the virus will still be able to spread in some populations in some parts of the world, other variants will pop up.”
-
AstraZeneca is working to produce a version of its vaccine that can protect against the variant from South Africa by the fall.Still, the findings rattled scientists, undercutting the notion that vaccines alone will stop the spread of the virus anytime soon. And they led to new, and more urgent, demands that richer countries donate doses to poorer countries that could become breeding grounds for mutations if the virus spreads unchecked.
- ...4 more annotations...
-
he B.1.351 variant has already spread beyond South Africa to neighboring countries, the United States and Britain. Scientists believe one of its mutations may make it harder for antibodies to grab onto the virus and keep it from entering cells.Among scientists’ worries is that the variant first detected in Britain has acquired the same mutation, known as E484K, in some cases.
-
Because the trial participants in South Africa were relatively young and unlikely to become severely ill, it was impossible for the scientists to determine if the vaccine protected people from hospitalization or death. Immune responses detected in blood samples from vaccinated people suggest it could.
-
Like many developing countries, South Africa was relying on the relatively cheap and easy-to-store AstraZeneca shot — “the people’s vaccine,” as Ms. Taylor put it — to tamp down new outbreaks. When airport workers rolled vaccine crates out of the belly of an airplane last week, President Cyril Ramaphosa watched from the rain-soaked tarmac.
-
Given the proven safety of the AstraZeneca vaccine and the hope that it might yet prevent hospitalizations and deaths from the new variant, Professor Venter said that health officials should consider offering it to anyone who wanted it.