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Matti Narkia

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal muc... - 0 views

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    Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier.
    Kong J, Zhang Z, Musch MW, Ning G, Sun J, Hart J, Bissonnette M, Li YC.
    Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G208-16. Epub 2007 Oct 25.
    PMID: 17962355

    These observations suggest that VDR plays a critical role in mucosal barrier homeostasis by preserving the integrity of junction complexes and the healing capacity of the colonic epithelium. Therefore, vitamin D deficiency may compromise the mucosal barrier, leading to increased susceptibility to mucosal damage and increased risk of IBD.
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