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Northeastern University psychology professor Lisa Feldman Barrett found, for the first time, that the neurotransmitter dopamine is involved in human bonding, bringing the brain's reward system into our understanding of how we form human attachments.

To conduct the study, the researchers turned to a novel technology: a machine capable of performing two types of brain scans simultaneously -- functional magnetic resonance imaging, or fMRI, and positron emission tomography, or PET.

Barrett's team focused on the neurotransmitter dopamine, a chemical that acts in various brain systems to spark the motivation necessary to work for a reward.

Puzzle-solving science, according to Kuhn, can therefore trigger a scientific revolution as scientists struggle to explain these anomalies and develop a novel basic theory to incorporate them into the existing body of knowledge. After an extended period of upheaval, in which followers of the new theory storm the bastions of accepted dogma, the old paradigm is gradually replaced.

biology is heading towards a similar scientific revolution that may shatter one of its most central paradigms. The discovery of a few small proteins with anomalous behaviour is about to overcome a central tenet of molecular biology: that information flows unidirectionally from the gene to the protein to the phenotype. It started with the discovery that prions, a class of small proteins that can exist in different forms, cause a range of highly debilitating diseases. This sparked further research

Scientific revolutions are still rare in biology, given that the field, unlike astronomy or physics, is relatively young.

Cohen outlined a vision of 'Net-enabled scholarly publishing that I can only think to call the aggregation model: editorial committees scanning the 'Net to find the most interesting scholarly content in a given field or discipline, and highlighting it through websites and e-mail blasts that hearken back to the early days when weblogs were literally just collections of links with one- or two-sentence summaries attached. (An example, edited by Cohen and some of his associates: Digital Humanities Now.) Some of that work consists of traditional books and articles, but much of it consists of blog posts, online debates, etc. This model gives us scholarly work from the bottom up, instead of generating published scholarly work by tossing a piece into the random crapshoot of putatively blind peer-review and crossing your fingers to see what happens. It also gives us scholarly work that can be certified as such by the collective deliberation of the community, which "votes" for pieces and ideas by reading them, recirculating them, linking to them, and other signs of interest and approval that can be easily tracked with traffic-tracing tools. And then, on top of that editorial aggregation -- Cohen made a great point that this kind of aggregation shouldn't be fully automated, because automated tools reward "loudmouths" and popular voices that just get retweeted a lot; human editors can do a lot to surface novel insights and new voices -- an open-access journal that curates the best of those linked items into published pieces, perhaps with some revisions and peer review/commentary.

one theme emerges from the media coverage of people's relationships with our current set of technologies: Consumers want digital willpower. App designers in touch with the latest trends in behavioral modification--nudging, the quantified self, and gamification--and good old-fashioned financial incentive manipulation, are tackling weakness of will. They're harnessing the power of payouts, cognitive biases, social networking, and biofeedback. The quantified self becomes the programmable self.

the trend still has multiple interesting dimensions

Individuals are turning ever more aspects of their lives into managerial problems that require technological solutions. We have access to an ever-increasing array of free and inexpensive technologies that harness incredible computational power that effectively allows us to self-police behavior everywhere we go. As pervasiveness expands, so does trust.

The research team performed brain scans on 24 college students and recent graduates, both before and after they spent 100 hours studying for the LSAT over a three-month period. The researchers also scanned 23 young adults who didn't study for the test. For those who studied, the results showed increased connectivity between the frontal lobes of the brain, as well as between the frontal and parietal lobes, which are parts of the brain associated with reasoning and thinking.

The study focused on fluid reasoning—the ability to tackle a novel problem—which is a central part of IQ tests and can to some degree predict academic performance or ability in demanding careers.

"People assume that IQ tests measure some stable characteristic of an individual, but we think this whole assumption is flawed," said Silvia Bunge, the study's senior author. "We think the skills measured by an IQ test wax and wane over time depending on the individual's level of cognitive activity."

Could the emotional connotations of words in literature be a kind of lagging economic indicator? According to scientists who analyzed a century’s worth of writing, they might: After using big-data techniques to document the frequency of sad and happy words in millions of books, the researchers concluded that the emotional mood of literature reflects the mood of the economy over the previous 10 years.

They then matched that against a well-known indicator called the “economic misery index” — the sum of inflation rates and unemployment rates — and found that literary misery in a given year correlated with the average of the previous decade’s economic misery index numbers.

“To me it confirms that we do have a collective memory that conditions the way we write, and that economics is a very important driver of that.”

Wasn’t the Enlightenment supposed to wash the world of its sins of superstition and religion? And yet humanity keeps clinging to its belief systems, its religious leaders, and its prayer. More than that, we’re dipping back into the magical realms — one would think that if superstition were to be eradicated through the power of reason and rationality, magic would be the first to go. It turns out our hunger for the irrational and the intuitive is more insatiable than previously assumed. We have our Kabbalah, our Chaos Magick, our Druids. We have our mystics and tarot card readers and our astrologers on morning news shows explaining why Kate and William are a match made by the gods. Wicca is a fast growing religion in the United States, and my German health insurance covers homeopathy and Reiki massage, both of which have always felt more like magic than science to me.

And yet the atheists keep on, telling us that we don’t have to believe in God. It maybe never occurred to them that perhaps we want to.

Magical belief, whether that entails an omnipotent God who watches over us or the conviction that we can communicate with “the other side,” fills a need in us. Some of us, I should say, as atheists would be quick to counter. How seriously we take that belief, and what we do with it varies from person to person. As the debates between the godless and the faithful continue — and these are so prevalent in our culture now, the religious figure versus the atheist, sponsored by every university and cultural center, that I read such a debate in a novel I had picked up — that perhaps these two kinds of people simply have a different set of needs. It’s like a new mother arguing with a woman who has never felt maternal a day in her life. Neither side will ever truly understand the longings of the other, and the fact that they can’t stop arguing and trying to convince is proof of that.

editor Jocelyn Glei and her team at Behance’s 99U pull together another package of practical wisdom from 21 celebrated creative entrepreneurs. Despite the somewhat self-helpy, SEO-skewing title, this compendium of advice is anything but contrived. Rather, it’s a no-nonsense, experience-tested, life-approved cookbook for creative intelligence, exploring everything from harnessing the power of habit to cultivating meaningful relationships that enrich your work to overcoming the fear of failure.

If the twentieth-century career was a ladder that we climbed from one predictable rung to the next, the twenty-first-century career is more like a broad rock face that we are all free-climbing. There’s no defined route, and we must use our own ingenuity, training, and strength to rise to the top. We must make our own luck.

Lucky people take advantage of chance occurrences that come their way. Instead of going through life on cruise control, they pay attention to what’s happening around them and, therefore, are able to extract greater value from each situation… Lucky people are also open to novel opportunities and willing to try things outside of their usual experiences. They’re more inclined to pick up a book on an unfamiliar subject, to travel to less familiar destinations, and to interact with people who are different than themselves.

Are there things we should try not to know?

IBM says that 2.5 quintillion bytes of data are created each day. That is a number both unimaginable and somewhat unhelpful to real understanding. It’s not just the huge scale of the information, after all, it’s the novel types of data

many participants expressed concern about the effects all this data would have on the ability of powerful institutions to control people, from state coercion to product marketing.

subjects — 780 New Haven residents who volunteered — helped make an untenured assistant professor named Stanley Milgram a national celebrity. Over the next five decades, his obedience experiments provided the inspiration for films, fiction, plays, documentaries, pop music, prime-time dramas, and reality television. Today, the Milgram experiments are considered among the most famous and most controversial experiments of all time. They are also often used in expert testimony in cases where situational obedience leads to crime

Perry’s evidence raises larger questions regarding a study that is still firmly entrenched in American scientific and popular culture: if Milgram lied once about his compromised neutrality, to what extent can we trust anything he said? And how could a blatant breach in objectivity in one of the most analyzed experiments in history go undetected for so long?

the debate has never addressed this question: to what extent can we trust his raw data in the first place? In her riveting new book, Behind the Shock Machine: The Untold Story of the Notorious Milgram Psychology Experiments, Australian psychologist Gina Perry tackles this very topic, taking nothing for granted

The portraits seem to be asking a lot of impolite questions: Do you have as many friends as we do? How did you celebrate your birthday? Do you regularly drink prosecco over plates of fruit at Ralph Lauren’s Polo Bar? Have you betrayed your gender by preferring the company of men? You don’t have a friend with whom you publicly exchange photographs of your manicures? What’s wrong with you? If female friendship is so uplifting, then why do these photos make us feel the opposite — unbalanced and unsure?

I used to think that friendship as performed for an audience would end with middle school, but the past 10 years of technology have changed that expectation.

In social media, friendship gets fixed and mounted. It loses its dramatic tension. It becomes a presentation of happiness, an advertisement for friendship rather than an actual portrayal of it.

James H. Simons likes to play against type. He is a billionaire star of mathematics and private investment who often wins praise for his financial gifts to scientific research and programs to get children hooked on math.But in his Manhattan office, high atop a Fifth Avenue building in the Flatiron district, he’s quick to tell of his career failings.He was forgetful. He was demoted. He found out the hard way that he was terrible at programming computers. “I’d keep forgetting the notation,” Dr. Simons said. “I couldn’t write programs to save my life.”After that, he was fired.His message is clearly aimed at young people: If I can do it, so can you.

Down one floor from his office complex is Math for America, a foundation he set up to promote math teaching in public schools. Nearby, on Madison Square Park, is the National Museum of Mathematics, or MoMath, an educational center he helped finance. It opened in 2012 and has had a quarter million visitors.

Dr. Simons received his doctorate at 23; advanced code breaking for the National Security Agency at 26; led a university math department at 30; won geometry’s top prize at 37; founded Renaissance Technologies, one of the world’s most successful hedge funds, at 44; and began setting up charitable foundations at 56.

the real question is not so much ‘What is genius?’ or even ‘Who is a genius?’ but rather, ‘What stake do we have in the whole idea of genius?’ or even, ‘Who’s asking and what’s behind their question?’

These are the issues I address in my new book by looking at the different views and theories of genius over the course of three centuries, from the start of the eighteenth century to the present day.

I concentrated on France, partly because French literature and intellectual history happen to be my area of expertise and personal interest; partly because the French contribution to the literature on genius hasn’t received its due; but mostly because the variety and the inventiveness of the views and theories of genius in France was a story worth telling for itself

literature's unrealities, literature's lies, are also a precious vehicle for the knowledge of the most hidden of human realities. The truths that it reveals are not always flattering; and sometimes the image of ourselves that emerges in the mirror of novels and poems is the image of a monster. This happens when we read about the horrendous sexual butchery fantasized by de Sade, or the dark lacerations and brutal sacrifices that fill the cursed books of Sacher-Masoch and Bataille. At times the spectacle is so offensive and ferocious that it becomes irresistible. Yet the worst in these pages is not the blood, the humiliation, the abject love of torture; the worst is the discovery that this violence and this excess are not foreign to us, that they are a profound part of humanity.

prophecy

Where are we humans going, as a species? If science fiction is any guide, we will genetically evolve like in X-Men, become genetically engineered as in Gattaca, or become cybernetically enhanced like General Grievous in Star Wars.

There is, however, another avenue for human evolution, one mostly unappreciated in both science and fiction. It is this unheralded mechanism that will usher in the next stage of human, giving future people exquisite powers we do not currently possess, powers worthy of natural selection itself. And, importantly, it doesn’t require us to transform into cyborgs or bio-engineered lab rats. It merely relies on our natural bodies and brains functioning as they have for millions of years. This mystery mechanism of human transformation is neuronal recycling, coined by neuroscientist Stanislas Dehaene, wherein the brain’s innate capabilities are harnessed for altogether novel functions.

The root of these misconceptions is the radical underappreciation of the design engineered by natural selection into the powers implemented by our bodies and brains, something central to my 2009 book, The Vision Revolution. For example, optical illusions (such as the Hering) are not examples of the brain’s poor hardware design, but, rather, consequences of intricate evolutionary software for generating perceptions that correct for neural latencies in normal circumstances.

Common readers—which is to say the great majority of people who continue to read—read for one purpose and one purpose only. They read for pleasure. They read to be entertained. They read to be diverted, assuaged, comforted, and tickled.

Reading, where it exists at all, has largely become an unprofitable wing of the diversion industry.

it's not only the division of experience between hard labor and empty leisure that now makes reading for something like mortal stakes a very remote possibility.

Wilson told me the new proposed evolutionary model pulls the field “out of the fever swamp of kin selection,” and he confidently predicted a coming paradigm shift that would promote genetic research to identify the “trigger” genes that have enabled a tiny number of cases, such as the ant family, to achieve complex forms of cooperation.

In the book, he proposes a theory to answer what he calls “the great unsolved problem of biology,” namely how roughly two dozen known examples in the history of life—humans, wasps, termites, platypodid ambrosia beetles, bathyergid mole rats, gall-making aphids, one type of snapping shrimp, and others—made the breakthrough to life in highly social, complex societies. Eusocial species, Wilson noted, are by far “the most successful species in the history of life.”

Summarizing parts of it for me, Wilson was particularly unsparing of organized religion, likening the Book of Revelation, for example, to the ranting of “a paranoid schizophrenic who was allowed to write down everything that came to him.” Toward philosophy, he was only slightly kinder. Generation after generation of students have suffered trying to “puzzle out” what great thinkers like Socrates, Plato, and Descartes had to say on the great questions of man’s nature, Wilson said, but this was of little use, because philosophy has been based on “failed models of the brain.”

“The Hangman’s Daughter” was an e-book hit. Amazon bought the rights to the historical novel by a first-time writer, Oliver Pötzsch, and had it translated from German. It has now sold 250,000 digital copies.

The characters in Gary Shteyngart’s novel “Super Sad True Love Story” inhabit a continuously surveilled and scored society.

Consider the protagonist, Lenny Abramov, age 39. A digital dossier about him accumulates his every health condition (high cholesterol, depression), liability (mortgage: $560,330), purchase (“bound, printed, nonstreaming media artifact”), tendency (“heterosexual, nonathletic, nonautomotive, nonreligious”) and probability (“life span estimated at 83”). And that profile is available for perusal by employers, friends and even strangers in bars.

Even before the appearance of these books, a report called “The Scoring of America” by the World Privacy Forum showed how analytics companies now offer categorization services like “churn scores,” which aim to predict which customers are likely to forsake their mobile phone carrier or cable TV provider for another company; “job security scores,” which factor a person’s risk of unemployment into calculations of his or her ability to pay back a loan; “charitable donor scores,” which foundations use to identify the households likeliest to make large donations; and “frailty scores,” which are typically used to predict the risk of medical complications and death in elderly patients who have surgery.

Antibiotics: US discovery labelled 'game-changer' for medicine

The decades-long drought in antibiotic discovery could be over after a breakthrough by US scientists.

ielded 25 new antibiotics, with one deemed "very promising".