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Lawrence Hrubes

Can Brain Science Be Dangerous? - NYTimes.com - 2 views

  • The idea that poverty can change the brain has gotten significant attention recently, and not just from those lay readers (a minority, according to recent research) who spend a lot of time thinking about neuroscience. Policy makers and others have begun to apply neuroscientific principles to their thinking about poverty — and some say this could end up harming poor people rather than helping. At The Conversation, the sociologist Susan Sered takes issue with “news reports with headlines like this one: ‘Can Brain Science Help Lift People Out Of Poverty?’” She’s referring to a June story by Rachel Zimmerman at WBUR, about a nonprofit called Crittenton Women’s Union that aims to use neuroscience to help get people out of poverty. Elisabeth Babcock, Crittenton’s chief executive, tells Ms. Zimmerman: “What the new brain science says is that the stresses created by living in poverty often work against us, make it harder for our brains to find the best solutions to our problems. This is a part of the reason why poverty is so ‘sticky.’”
  • “The new neuroscience offers wonderful possibilities regarding Alzheimer’s disease, epilepsy, brain injuries and much more,” writes Dr. Sered. “But scientific knowledge always develops and is utilized within social contexts.” She and others fear that, used incorrectly, neuroscience might spread the view that poor people are lesser than others, that they are irrevocably debilitated by their experiences with poverty — or, conversely, that if they fail to respond to programs that science says will help them, it must be their own fault.
  • Ms. Williams writes that many of today’s child-development ideas are very similar to those of the psychiatrist John Bowlby’s work on attachment theory. But, she notes, he developed his ideas through psychological observation, not brain scans. And she quotes Sebastian Kraemer, a psychiatrist: “If John Bowlby were alive today, he would say, this [neuroscience] does not add anything. People are just more persuaded by it, by the facts and the pictures.” People do seem to find neuroscience extremely persuasive, even when it’s wrong. And this may be part of what critics fear — that images and facts about the brain are so powerful, they can make us believe things we really shouldn’t.
Lawrence Hrubes

Lights Out: A New Reckoning for Brain Death : The New Yorker - 0 views

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    "But brain death is not quite as certain as these bioethicists might like. A doctor can't always determine whether the brain is truly dead. The diagnosis is made the old-fashioned way: by careful observation. A doctor checks to see whether the eyes are responsive to light or touch; she pricks the nailbeds to discern whether the pain registers; she tests muscle reflexes; she determines whether the buildup of carbon dioxide triggers spontaneous breathing if the ventilator is shut off; and she may use an electroencephalograph to detect electrical activity in the brain. (However, even a dead brain may produce some voltage.) If all the findings are negative, then the declaration is made. Even then, the doctor can be wrong. "
Lawrence Hrubes

The Brain That Couldn't Remember - The New York Times - 0 views

  • In that pantheon of illuminatingly broken men and women, Henry stands apart. It is difficult to exaggerate the impact he has had on our understanding of ourselves. Before Brenda Milner collaborated on that first paper about Henry, the prevailing theory of memory held that its functions could not be localized to a single cortical area, that learning was distributed across the brain as a whole. By that theory — built upon the experimental lesioning of the brains of rats — a person’s memory would be affected only in proportion to the amount of brain tissue removed, regardless of which brain structures the tissue was removed from. Milner’s first paper about Henry, along with her previous work, upended this view.
  • Five years after Milner’s first paper about Henry, she published a second that was almost as revelatory. That paper documented Henry’s gradual improvement over a three-day period on a difficult hand-eye coordination task. His improvement came despite his inability to ever remember his previous attempts at the task, indicating that there are at least two different memory systems in the brain — one responsible for our conscious, episodic memories, the second responsible for task-or-skill related “procedural” memories — and that these two systems seem to rely on entirely distinct parts of the brain. This was another fundamental step forward in our understanding of how memory works. Together, Milner’s two Henry-­related revelations can be viewed as the cornerstones of modern memory science.
  • Corkin: Yeah, but it’s not peer-­reviewed, for one thing. That’s important. The stuff that’s published is good stuff. Peer-­reviewed. You can believe it. Things that, you know, experiments that might not have been good experiments, there might have been inadequate control groups. ... There are all sorts of things that can go wrong with experiments. Not every experiment is publishable.
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  • Me: But they can still be interpreted by other people. ... Maybe as we continue to understand how the brain works, and how memory works, some of this existing data of H.M.’s could be reilluminated by new theories, by new ideas, by new — it just seems a shame to destroy it. And it also seems — and this would be the darker interpretation of it — it locks in stone your own telling of H.M.’s story.
Lawrence Hrubes

You're an Adult. Your Brain, Not So Much. - The New York Times - 0 views

  • Leah H. Somerville, a Harvard neuroscientist, sometimes finds herself in front of an audience of judges. They come to hear her speak about how the brain develops.It’s a subject on which many legal questions depend. How old does someone have to be to be sentenced to death? When should someone get to vote? Can an 18-year-old give informed consent?
  • Eventually this reshaping slows, a sign that the brain is maturing. But it happens at different rates in different parts of the brain.The pruning in the occipital lobe, at the back of the brain, tapers off by age 20. In the frontal lobe, in the front of the brain, new links are still forming at age 30, if not beyond.“It challenges the notion of what ‘done’ really means,” Dr. Somerville said.
Lawrence Hrubes

The New Science of Mind - NYTimes.com - 0 views

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    This new science of mind is based on the principle that our mind and our brain are inseparable. The brain is a complex biological organ possessing immense computational capability: it constructs our sensory experience, regulates our thoughts and emotions, and controls our actions. It is responsible not only for relatively simple motor behaviors like running and eating, but also for complex acts that we consider quintessentially human, like thinking, speaking and creating works of art. Looked at from this perspective, our mind is a set of operations carried out by our brain. The same principle of unity applies to mental disorders.
Lawrence Hrubes

Annals of Medicine: As Good as Dead : The New Yorker - 1 views

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    "Confusion about the concept of brain death is not unusual, even among the transplant professionals, surgeons, neurologists, and bioethicists who grapple with it regularly. Brain death is confusing because it's an artificial distinction constructed, more than thirty years ago, on a conceptual foundation that is unsound. Recently, some physicians have begun to suggest that brain-dead patients aren't really dead at all-that the concept is just the medical profession's way of dodging ethical questions about a practice that saves more than fifteen thousand lives a year."
Lawrence Hrubes

Henry Gustave Molaison: The Basis for 'Memento' and the World's Most Celebrated Amnesia... - 0 views

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    "Scoville later called the operation "a tragic mistake" and warned neurosurgeons never to repeat it, but neuroscience and cognitive psychology benefitted hugely. The operation could not have been better designed if the intent had been to create a new kind of experimental object that showed where in the brain memory lived: there was no other way that Molaison's brain injuries could have occurred, and no other way that the precision of his memory damage could have been brought about. Molaison gave scientists a way to map cognitive functions onto brain structures. It became possible to subdivide memory into different types and to locate their cerebral Zip Codes."
Lawrence Hrubes

On the Brain - The New Yorker - 1 views

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    This is an archive of various NYer articles about the brain. Many links to areas of knowledge.
Lawrence Hrubes

Will You Ever Be Able to Upload Your Brain? - The New York Times - 1 views

  • I am a theoretical neuroscientist. I study models of brain circuits, precisely the sort of models that would be needed to try to reconstruct or emulate a functioning brain from a detailed knowledge of its structure. I don’t in principle see any reason that what I’ve described could not someday, in the very far future, be achieved (though it’s an active field of philosophical debate). But to accomplish this, these future scientists would need to know details of staggering complexity about the brain’s structure, details quite likely far beyond what any method today could preserve in a dead brain.
markfrankel18

The Brain on Trial - Issue 5: Fame - Nautilus - 0 views

  • Now we are regularly bombarded with new insights into how the unconscious guides our behavior. At the same time, neuroscience has largely debunked the idea of an autonomous self that has the final say in decisions; few science-savvy folks still believe there is a “ghost in the machine,” a little homunculus in the brain who is watching our perceptions or thinking our thoughts. Some philosophers even question whether the conscious mind plays any role in our thoughts. In short, present-day neuroscience has pulled the rug out from under the concept of “the rational man.”
  • If you are asked why you chose the violin, your answer is unlikely to be an accurate reflection of the unconscious competition that led to your choice. In effect, the decision happened to you. Your brain developed a “violin neural circuit” in the same way that fame makes some actors, musicians, and novelists superstars while others, for reasons that are never entirely clear, are relegated to obscurity.
  • Imagine that you are a juror assigned to the sentencing phase of a person convicted of first-degree murder. The defendant is a 33-year-old woman who has confessed to shooting her boyfriend in the head, then stabbing him nearly 30 times before unsuccessfully trying to decapitate him with a butcher knife. Initially she tells police she hadn’t been present, that her boyfriend had been killed by “unknown intruders.” When she can offer no evidence to substantiate her alibi, she then confesses, arguing self-defense and that her boyfriend had submitted her to prior physical and mental abuse. On a national TV news show, she predicts that no jury will find her guilty, yet after a several-month trial, you find her guilty of first-degree murder. It is now sentencing time. Your assignment is to determine whether the crime warrants the death penalty or a life sentence without parole, or a lesser sentence with the possibility of parole.
Lawrence Hrubes

Daniel Dennett's Science of the Soul - The New Yorker - 0 views

  • In “Consciousness Explained,” a 1991 best-seller, he described consciousness as something like the product of multiple, layered computer programs running on the hardware of the brain. Many readers felt that he had shown how the brain creates the soul. Others thought that he’d missed the point entirely. To them, the book was like a treatise on music that focussed exclusively on the physics of musical instruments. It left untouched the question of how a three-pound lump of neurons could come to possess a point of view, interiority, selfhood, consciousness—qualities that the rest of the material world lacks. These skeptics derided the book as “Consciousness Explained Away.”
  • The physicalists believe, with Dennett, that science can explain consciousness in purely material terms. The dualists believe that science can uncover only half of the picture: it can’t explain what Nabokov called “the marvel of consciousness
Lawrence Hrubes

BBC News - Artists 'have structurally different brains' - 1 views

  • Artists have structurally different brains compared with non-artists, a study has found. Participants' brain scans revealed that artists had increased neural matter in areas relating to fine motor movements and visual imagery. The research, published in NeuroImage, suggests that an artist's talent could be innate. But training and environmental upbringing also play crucial roles in their ability, the authors report. As in many areas of science, the exact interplay of nature and nurture remains unclear.
markfrankel18

When are you dead? - 2011 SPRING - Stanford Medicine Magazine - Stanford University Sch... - 0 views

  • A little more than 40 years ago, a partially functioning brain would not have gotten in the way of organ donation; irreversible cardiopulmonary failure was still the only standard for determining death. But during the 1970s, that began to change, and by the early 1980s, the cessation of all brain activity — brain death — had become a widely accepted standard. In the transplant community, brain death was attractive for one particular reason: The bodies of such donors could remain on respirators to keep their organs healthy, even during much of the organ-removal surgery. Today, the medical establishment, facing a huge shortage of organs, needs new sources for transplantation. One solution has been a return to procuring organs from patients who die of heart failure. Before dying, these patients are likely to have been in a coma, sustained by a ventilator, with very minimal brain function — a hopeless distance from what we mean by consciousness. Still, many people, including some physicians, consider this type of organ donation, known as “donation after cardiac death” or DCD, as akin to murder.
markfrankel18

Why can't the world's greatest minds solve the mystery of consciousness? | Oliver Burke... - 0 views

  • There was only one truly hard problem of consciousness, Chalmers said. It was a puzzle so bewildering that, in the months after his talk, people started dignifying it with capital letters – the Hard Problem of Consciousness – and it’s this: why on earth should all those complicated brain processes feel like anything from the inside? Why aren’t we just brilliant robots, capable of retaining information, of responding to noises and smells and hot saucepans, but dark inside, lacking an inner life? And how does the brain manage it? How could the 1.4kg lump of moist, pinkish-beige tissue inside your skull give rise to something as mysterious as the experience of being that pinkish-beige lump, and the body to which it is attached?
  • in recent years, a handful of neuroscientists have come to believe that it may finally be about to be solved – but only if we are willing to accept the profoundly unsettling conclusion that computers or the internet might soon become conscious, too.
markfrankel18

This is your brain on knockoffs: The science of how we trick ourselves into not believi... - 0 views

  • In 2011, Martin Kemp, an Oxford art history professor, ran an experiment referenced in Ragai’s book, in which 14 non-specialists were shown genuine and fake “Rembrandt” paintings while undergoing brain scans. A painting was shown to them and they were told it was by Rembrandt. Another painting was shown to them and they were told it was a fake. By measuring the pleasure centers of the brain, Kemp concluded that “the way we view art is not rational.” Being told a work was authentic (whether or not it actually was) activated pleasure centers when it was shown, which was not the case when the viewer was told it was inauthentic (even if it was actually the real deal). It’s all about anticipation. If you’re poured a glass of wine and told it’s a 1955 Chateau Lafite Rothschild, you’ll enjoy it much more than if you’re told it’s a 2015 Trader Joe’s wine-in-a-box, whichever it truly happens to be. (For more on this, see my eBook single on wine forgery).
  • But while non-experts are led by being told what is authentic and what is not, clever forgers do a more elaborate version of the same thing to snare specialists. Rather than telling them “this is authentic,” which would summon a defensive reaction on the part of the expert (“Oh yeah, I’m the expert here, I’ll tell you what’s authentic and what isn’t”), they lay a trail of traps by scattering subtle clues that lead the expert into following a carefully plotted trail, but to come to their own conclusion about the authenticity of the work in question.
Lawrence Hrubes

BBC News - The difficult task of reading the brain - 0 views

  • Neuroscience is a fast growing and popular field, but despite advances, when an area of the brain 'lights up" it does not tell us as much as we'd like about the inner workings of the mind. Many of us have seen the pictures and read the stories. A beautiful picture of the brain where an area is highlighted and found to be fundamental for processes like fear, disgust or impaired social ability. There are so many stories it can be easy to be swayed into thinking that much more of the brain's mystery has been solved than is the case.
Lawrence Hrubes

How the Brain Stores Trivial Memories, Just in Case - NYTimes.com - 0 views

  • The surge of emotion that makes memories of embarrassment, triumph and disappointment so vivid can also reach back in time, strengthening recall of seemingly mundane things that happened just beforehand and that, in retrospect, are relevant, a new study has found.The report, published Wednesday in the journal Nature, suggests that the television detective’s standard query — “Do you remember any unusual behavior in the days before the murder?” — is based on solid brain science, at least in some circumstances.The findings fit into the predominant theory of memory: that it is an adaptive process, continually updating itself according to what knowledge may be important in the future.The new study suggests that human memory has, in effect, a just-in-case file, keeping seemingly trivial sights, sounds and observations in cold storage for a time in case they become useful later on.
markfrankel18

Time-shifting man predicts the future › Dr Karl's Great Moments In Science (A... - 0 views

  • "Time" is something that both philosophers and physicists have been wondering for about, well, a long time. And now, the neuroscientists have joined in. They have found a man who, when he looks at you, hears what you are saying to him before your lips move.
  • We don't notice this delay in reality because we have evolved to be able to deal with this. We can anticipate actions or patterns through experience.
  • Now you might not realise this, but in terms of vision you are always living 0.3 second (or 300 milliseconds) behind reality. That's how long it takes between when the incoming light lands on the cells in your retina, and you get that full magnificent wraparound 3D colour sensation that we call vision.
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  • So how come we normally see the lips moving at the same time as we hear the voice? Almost certainly, it's because our brain deliberately inserts a delay of about 200 milliseconds on the audio circuit. Now sure, there would be an advantage in being able to hear dangerous things, such as the killer kangaroo bearing down upon you that extra 200 milliseconds earlier. But all of us are a product of an evolutionary pathway that decided it was more important for us to be able to easily communicate with our fellow humans, than to hear the killer kangaroo that 200 milliseconds sooner. After all, we humans are quite pathetic as a hunting animal. We can't run very quickly, our eyes are not very sharp, and neither is our sense of smell. Our claws are silly little fingernails, and our teeth are not very good at ripping and tearing. But thanks to our amazing brain, we can organise ourselves into groups and so we have become masters of the planet. So, getting back to Mr PH, if the sound of the outside world was deliberately electronically delayed by 200 milliseconds, suddenly audio and vision were in sync for him again. And when the neuroscientists did an MRI scan on his brain, they found damage in areas that were well-placed to disrupt audition and/or timing.
Lawrence Hrubes

BBC News - Sleep's memory role discovered - 0 views

  • The mechanism by which a good night's sleep improves learning and memory has been discovered by scientists. The team in China and the US used advanced microscopy to witness new connections between brain cells - synapses - forming during sleep. Their study, published in the journal Science, showed even intense training could not make up for lost sleep. Experts said it was an elegant and significant study, which uncovered the mechanisms of memory. It is well known that sleep plays an important role in memory and learning. But what actually happens inside the brain has been a source of considerable debate.
Lawrence Hrubes

The Power of Touch - The New Yorker - 0 views

  • At a home in the Romanian city of Iași, Carlson measured cortisol levels in a group of children ranging from two months to three years old. The caregiver-to-child ratio was twenty to one, and most of the children had experienced severe neglect and sensory deprivation. Multiple times a day, Carlson took saliva samples, tracking how cortisol levels fluctuated in response to stressful events. The children, she found, were hormonally off kilter. Under normal conditions, cortisol peaks just before we wake up and then tapers off; in the leagăne infants, it peaked in the afternoon and remained elevated. Those levels, in turn, correlated with faltering performance on numerous cognitive and physical assessments. Then Carlson tried an intervention modelled on the work of Joseph Sparling, a child-development specialist, and the outcomes changed. When half of the orphans received more touching from more caregivers—an increase in hugs, holding, and the making of small adjustments to clothes and hair—their performance markedly improved. They grew bigger, stronger, and more responsive, both cognitively and emotionally, and they reacted better to stress.
  • Touch is the first of the senses to develop in the human infant, and it remains perhaps the most emotionally central throughout our lives. While many researchers have appreciated its power, others have been more circumspect. Writing in 1928, John B. Watson, one of the originators of the behaviorist school of psychology, urged parents to maintain a physical boundary between themselves and their children: “Never hug and kiss them, never let them sit on your lap. If you must, kiss them once on the forehead when they say goodnight. Shake hands with them in the morning. Give them a pat on the head if they have made an extraordinarily good job on a difficult task.” Watson acknowledged that children must be bathed, clothed, and cared for, but he believed that excessive touching—that is, caressing—would create “mawkish” adults. An untouched child, he argued, “enters manhood so bulwarked with stable work and emotional habits that no adversity can quite overwhelm him.” Now we know that, to attain that result, he should have suggested the opposite: touch, as frequent and as caring as possible
  • And yet touch is rarely purely physical. Field’s more recent work has shown that the brain is very good at distinguishing an emotional touch from a similar, but non-emotional, one. A massage chair is not a masseuse. Certain touch receptors exist solely to convey emotion to the brain, rather than sensory information about the external environment. A recent study shows that we can identify other people’s basic emotions based on how they touch us, even when they are separated from us by a curtain. And the emotions that are communicated by touch can go on to shape our behavior. One recent review found that, even if we have no conscious memory of a touch—a hand on the shoulder, say—we may be more likely to agree to a request, respond more (or less) positively to a person or product, or form closer bonds with someone.
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