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Nathan Goodyear

Hypothalamic IKKbeta/NF-kappaB and ER stress link ... [Cell. 2008] - PubMed result - 0 views

  • Our results show that the hypothalamic IKKbeta/NF-kappaB program is a general neural mechanism for energy imbalance underlying obesity and suggest that suppressing hypothalamic IKKbeta/NF-kappaB may represent a strategy to combat obesity and related diseases
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    INflammation of hypothalamus through NF-KappaB leads to obesity and related diseases
Nathan Goodyear

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity 10.1016/j.cell.2008.07.043 : Cell | ScienceDirect.com - 0 views

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    chronic overnutrition (ie overeating) results in activation of the IKKBeta/NF-kappaB complex, increase NF-kappaB transcription and inflammation.  This leads to ER (endoplasmic reticulum) stress
Nathan Goodyear

Astaxanthin Inhibits Nitric Oxide Production and Inflammatory Gene Expression by Suppressing IκB Kinase-dependent NF-κB Activation - 0 views

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    astaxanthin inhibits inflammation through NF-kappaB mediated NO.
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