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IKK-[beta] links inflammation to obesity-induced insulin resistance - Nature Medicine - 0 views

www.nature.com/...nm1185.html

inflammation insulin resistance IKK-Beta NF-kapppB

shared by Nathan Goodyear on 21 Dec 11 - No Cached

Nathan Goodyear on 21 Dec 11

inflammation plays critical role in insulin resistance and the associated inflammatory conditions. IKK-Beta and NF-KappaB are heavily involved in local and systemic inflammatory signaling.

<div class="cArrow"> </div><div class="cContentInner">inflammation plays critical role in insulin resistance and the associated inflammatory conditions. IKK-Beta and NF-KappaB are heavily involved in local and systemic inflammatory signaling.</div>

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Access : FFA-Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER S... - 0 views

www.nature.com/...oby2010200a.html

FFA inflammation overweight obesity free fatty acids insulin resistance IKK-Beta endoplasmic reticulum stress

shared by Nathan Goodyear on 21 Dec 11 - No Cached

Nathan Goodyear on 21 Dec 11

elevated FFA (free-fatty acids) shown to produce inflammation and insulin resistance through endoplasmic reticulum stress. The main target in this pathway is IKK-Beta overexpression.

<div class="cArrow"> </div><div class="cContentInner">elevated FFA (free-fatty acids) shown to produce inflammation and insulin resistance through endoplasmic reticulum stress. The main target in this pathway is IKK-Beta overexpression.</div>

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Toll-Like Receptor-4 Mediates Vascular Inflammation and Insulin Resistance in Diet-Indu... - 0 views

circres.ahajournals.org/...1589.short

inflammation insulin resistance obesity FFA saturated fat TLR4 NF-kappaB IKK-Beta

shared by Nathan Goodyear on 21 Dec 11 - No Cached

Nathan Goodyear on 21 Dec 11

high saturated fat intake (excess FFA) shown to contribute to obesity through TLR4 receptors. TLR4 receptors are mediators in the innate immunity. The result will be both IKK-Beta and NF-KappaB.

<div class="cArrow"> </div><div class="cContentInner">high saturated fat intake (excess FFA) shown to contribute to obesity through TLR4 receptors. TLR4 receptors are mediators in the innate immunity. The result will be both IKK-Beta and NF-KappaB.</div>

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Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance ... - 0 views

www.sciencedirect.com/...S0092867408010088

chronic overnutrition NF-kappaB IKK-Beta inflammation obesity overweight weight-loss ER endoplasmic reticulum stress

shared by Nathan Goodyear on 17 Jan 12 - No Cached

Nathan Goodyear on 17 Jan 12

chronic overnutrition (ie overeating) results in activation of the IKKBeta/NF-kappaB complex, increase NF-kappaB transcription and inflammation. This leads to ER (endoplasmic reticulum) stress

<div class="cArrow"> </div><div class="cContentInner">chronic overnutrition (ie overeating) results in activation of the IKKBeta/NF-kappaB complex, increase NF-kappaB transcription and inflammation. This leads to ER (endoplasmic reticulum) stress</div>

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