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review of 24 studies, some well designed and others not, lead to conclusion:  "We conclude that there is no scientific evidence that HCG is effective in the treatment of obesity; it does not bring about weight-loss of fat-redistribution, nor does it reduce hunger or induce a feeling of well-being."

there is no scientific evidence that HCG is effective in the treatment of obesity; it does not bring about weight-loss of fat-redistribution, nor does it reduce hunger or induce a feeling of well-being.

complex interplay between behavior, genetics, and CNS play role in over-eating.  Add in environment as well.

Ghrelin is a hormone that is release to induce hunger and eating. Post meals, gherlin should decrease; but in obese individuals, a dysregulation between the GI system and the hypothalamus results in elevated gherlin resulting in overeating.

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no improvement in weight loss with HCG injections above that in dietary changes. This isa duplication of the initial Asher-Harper study in 1973 that did show improvement in 20 women.  

HCG appears to be placebo effect

HCG no more effective than placebo in weight loss

HCG ineffective in weight loss in a double-blinded study