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in title, tags, annotations or urlUS Cancer Program (November 2011) Townsend Letter for Doctors & Patients - 0 views
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during 1975–2007 the US/NCI program was a failure in the prevention of 22 of the 24 cancers studied
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Only 2 of the 24 cancers showed success on the prevention side: cervical and stomach cancer
Renin-angiotensin system and cancer: A review - 0 views
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crucial role of the RAS in the development and maintenance of cancer
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kidneys, which produce renin in response to decreased arterial pressure, reduced sodium in the distal tubule, or sympathetic nervous system activity via the β-adrenergic receptors
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Renin is secreted from the juxtaglomerular cells into the bloodstream where it encounters angiotensinogen (AGN), normally produced by the liver
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Anticancer mechanisms of cannabinoids - 0 views
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modulating key cell signalling pathways involved in the control of cancer cell proliferation and survival
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cannabinoids inhibit angiogenesis and decrease metastasis in various tumour types in laboratory animals
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Cannabis sativa L. (marijuana)
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Ivermectin: enigmatic multifaceted 'wonder' drug continues to surprise and exceed expectations | The Journal of Antibiotics - 0 views
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The avermectins are known to possess pronounced antitumor activity
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Over the past few years, there have been steadily increasing reports that ivermectin may have varying uses as an anti-cancer agent, as it has been shown to exhibit both anti-cancer and anti-cancer stem cell properties
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In human ovarian cancer and NF2 tumor cell lines, high-dose ivermectin inactivates protein kinase PAK1 and blocks PAK1-dependent growth
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In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer | Proceedings of the National Academy of Sciences - 0 views
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we functionally validated a potent EOC oncogene, KPNB1, and showed its clinical relevance to human EOC
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a well-established antiparasitic drug, ivermectin, has antitumor effects on EOC through its inhibition of KPNB1
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EOC has high intertumor and intratumor heterogeneity at the molecular and epigenetic levels
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Substantial contribution of extrinsic risk factors to cancer development - 0 views
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Here we provide evidence that intrinsic risk factors contribute only modestly (<10~30%) to cancer development
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we conclude that cancer risk is heavily influenced by extrinsic factors. These results carry immense consequences for strategizing cancer prevention
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cancers are proposed to originate from the malignant transformation of normal tissue progenitor and stem cells
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বাংলাদেশ স্বাস্থ্য নিউজ আপডেট - সংবাদ মাধ্যম: ভারতের সার্ভিকাল স্পাইন সার্জনদের সাথে মানসম্পন্ন জীবনে ফিরে যান - 0 views
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