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Nathan Goodyear

Medical education in pharmacogenomics-results from a survey on pharmacogenetic knowledg... - 0 views

www.ncbi.nlm.nih.gov/...PMC5599468

genetics pharmacogenetics

shared by Nathan Goodyear on 17 Jan 18 - No Cached
  • Of participants, 84.3% found pharmacogenomics relevant to their current practice
  • More than two-thirds (65.7%) did not order nor recommend a pharmacogenomic test in the past year
  • pharmacogenomic testing was understood mainly for assessment of the variability of genes affecting drug disposition, metabolism and drug transport leading to individual responses to drugs
  • ...4 more annotations...
  • Pre-emptive, prospective, genotyping to make individualised drug therapy feasible is seen to contribute to personalised medicine
  • assumed to improve drug efficacy and safety
  • Potential benefits of pharmacogenomics (PGx) have been defined such as predicting intended response to medication by more accurate dosing, avoiding adverse drug reactions and therefore enhancing drug safety and reducing health care cost
  • survey among Dutch pharmacists revealed 14.7% recent users of PGx diagnostics [27], whereas in our cohort, the percentage was with 34.3% higher.
  • Nathan Goodyear on 17 Jan 18
     
    Doctors and pharmacists are slow to integrate pharmacogenetics. Good working definition of pharmacogenetics as well.
Nathan Goodyear

False-positive results released by direct-to-consumer genetic tests highlight the impor... - 0 views

www.nature.com/...gim201838

epigenetics pharmacogenetics cancer genetics cancer medicine

shared by Nathan Goodyear on 09 Apr 18 - No Cached
  • Nathan Goodyear on 09 Apr 18
     
    Consumers beware: direct to consumer genetic testing found to have 40% false positive rates with misclassification of variants. This also includes the interpretative reports that often accompany the direct to consumer genetic test companies or included from 3rd parties. This could have huge implications in the use of Epigenetics, pharmacogenetics, and Cancer genetics.  These genetic testing needs medical interpretation not algorithms.
Nathan Goodyear

Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possib... - 0 views

www.ajcn.org/...45

Capsaicin weight-loss overweight obesity metabolism capsiate

shared by Nathan Goodyear on 10 Feb 12 - No Cached
  • Nathan Goodyear on 10 Feb 12
     
    Capsaicin shown to aid weight loss.
Nathan Goodyear

G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications - 0 views

www.ncbi.nlm.nih.gov/...PMC4153881

glucose 6 phosphate dehydrogenase G6PD

shared by Nathan Goodyear on 13 Apr 20 - No Cached
  • Nathan Goodyear on 13 Apr 20
     
    To be read
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