Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle. - 0 views
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These results suggest that cortisol acts as a potent mineralocorticoid in 11 beta-OHSD deficiency
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major site for the oxidation of cortisol to cortisone is the kidney
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congenital deficiency of 11 beta-OHSD results in high intrarenal cortisol levels which then act on renal type I mineralocorticoid receptors
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