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Nathan Goodyear

Menopause and Ovariectomy Cause a Low Grade of Systemic Inflammation that May Be Preven... - 0 views

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    Menopausal rats and rats that had ovaries removed have increased low grade inflammatory signaling.  This study treated the rats in question with either Estradiol and Losartan and both decreased inflammatory signaling.
Nathan Goodyear

Effects of Angiotensin, Vasopressin and Aldosterone on Proliferation of MCF-7 Cells and... - 0 views

  • The renin-angiotensin system (RAS) has been associated with local tumor growth, inflammation, angiogenesis and facilitation of metastasis
  • Aldosterone and vasopressin did not alter cellular growth (Figure 1) and did not alter doxorubicin sensitivity
  • angiotensin increased the growth of MCF-7 cells
  • ...2 more annotations...
  • losartan
  • evidence that breast cancer chemotherapy can be influenced by anti-hypertensive treatment
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    upregulated RAS associated with stimulated breast cancer growth.  Anti-hypertensive therapy not only can it impact the cancer growth potential but also can augment chemotherapy.
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