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Nathan Goodyear

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352507/#:~:text=THC%20has%20been%20shown%... - 0 views

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    THC induces apoptosis via ceramide de novo synthesis
Nathan Goodyear

A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma | Molecu... - 0 views

  • Δ9-Tetrahydrocannabinol (THC; Supplementary Fig. 1), the main active component of the hemp plant Cannabis sativa
  • CB1, abundantly expressed in the brain and at many peripheral sites
  • CB2, expressed in the immune system and also present in some neuron subpopulations and glioma cells
  • ...3 more annotations...
  • antitumoral agents
  • Aside from THC, C. sativa produces approximately 70 other cannabinoids, although, unlike THC, many of them exhibit little affinity for CB receptors (10, 20). Of interest, at least one of these components, namely, cannabinol (CBD; Supplementary Fig. 1), has been shown to reduce the growth of different types of tumor xenografts including gliomas
  • the combined administration of THC and CBD is being therapeutically explored (10, 20, 26), although its effects on the proliferation and survival of cancer cells have only been analyzed in vitro
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    THC found to augment chemotherapy in the glioblastoma cell culture study.
Nathan Goodyear

Oncotarget | The heterogeneity and complexity of Cannabis extracts as antitumor agents - 0 views

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    Study reviews the different THC and CBD phytocannabinoids and their anti-cancer effect i.e. anti-proliferative, pro-apoptosis... Enough of the talk that MM has not anti-cancer benefits. Enough of the censorship!
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