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softtechworld

Website development and Design Company In India - 0 views

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    Softtech World is a leading Website development & Designing Company in India. We also specialize in Web designing, eCommerce & business applications. Get your dream website at cheapest price. For any query, Please write to us at:  info@softtechworld.com Or Call to us at: +91 9999819534 Or Visit at: http://www.softtechworld.com
Skeptical Debunker

What causes autism? Exploring the environmental contribution : Current Opinion in Pediatrics - 0 views

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    Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.
Skeptical Debunker

Human cells exhibit foraging behavior like amoebae and bacteria - 0 views

  • "As far as we can tell, this is the first time this type of behavior has been reported in cells that are part of a larger organism," says Peter T. Cummings, John R. Hall Professor of Chemical Engineering, who directed the study that is described in the March 10 issue of the Public Library of Science journal PLoS ONE. The discovery was the unanticipated result of a study the Cummings group conducted to test the hypothesis that the freedom with which different cancer cells move - a concept called motility - could be correlated with their aggressiveness: That is, the faster a given type of cancer cell can move through the body the more aggressive it is. "Our results refute that hypothesis—the correlation between motility and aggressiveness that we found among three different types of cancer cells was very weak," Cummings says. "In the process, however, we began noticing that the cell movements were unexpectedly complicated." Then the researchers' interest was piqued by a paper that appeared in the February 2008 issue of the journal Nature titled, "Scaling laws of marine predator search behaviour." The paper contained an analysis of the movements of a variety of radio-tagged marine predators, including sharks, sea turtles and penguins. The authors found that the predators used a foraging strategy very close to a specialized random walk pattern, called a Lévy walk, an optimal method for searching complex landscapes. At the end of the paper's abstract they wrote, "...Lévy-like behaviour seems to be widespread among diverse organisms, from microbes to humans, as a 'rule' that evolved in response to patchy resource distributions." This gave Cummings and his colleagues a new perspective on the cell movements that they were observing in the microscope. They adopted the basic assumption that when mammalian cells migrate they face problems, such as efficiently finding randomly distributed targets like nutrients and growth factors, that are analogous to those faced by single-celled organisms foraging for food. With this perspective in mind, Alka Potdar, now a post-doctoral fellow at Case Western Reserve University and the Cleveland Clinic, cultured cells from three human mammary epithelial cell lines on two-dimensional plastic plates and tracked the cell motions for two-hour periods in a "random migration" environment free of any directional chemical signals. Epithelial cells are found throughout the body lining organs and covering external surfaces. They move relatively slowly, at about a micron per minute which corresponds to two thousandths of an inch per hour. When Potdar carefully analyzed these cell movements, she found that they all followed the same pattern. However, it was not the Lévy walk that they expected, but a closely related search pattern called a bimodal correlated random walk (BCRW). This is a two-phase movement: a run phase in which the cell travels primarily in one direction and a re-orientation phase in which it stays in place and reorganizes itself internally to move in a new direction. In subsequent studies, currently in press, the researchers have found that several other cell types (social amoeba, neutrophils, fibrosarcoma) also follow the same pattern in random migration conditions. They have also found that the cells continue to follow this same basic pattern when a directional chemical signal is added, but the length of their runs are varied and the range of directions they follow are narrowed giving them a net movement in the direction indicated by the signal.
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    When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found. The discovery has a practical value for drug development: Incorporating this basic behavior into computer simulations of biological processes that involve cell migration, such as embryo development, bone remodeling, wound healing, infection and tumor growth, should improve the accuracy with which these models can predict the effectiveness of untested therapies for related disorders, the researchers say.
thinkahol *

Artificial hippocampal system restores long-term memory, enhances cognition | KurzweilAI - 2 views

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    Theodore Berger and his team at the USC Viterbi School of Engineering's Department of Biomedical Engineering have developed a neural prosthesis for rats that is able to restore their ability to form long-term memories after they had been pharmacologically blocked. In a dramatic demonstration, Berger blocked the ability to rats to form long-term memories by using pharmacological agents to disrupt the neural circuitry that communicates between two subregions of the hippocampus, CA1 and CA3, which interact to create long-term memory, prior research has shown. The rats were unable to remember which lever to pull to gain a reward, or could only remember for 5-10 seconds, when previously they could remember for a long period of time. The researchers then developed an artificial hippocampal system that could duplicate the pattern of interaction between CA3-CA1 interactions. Long-term memory capability returned to the pharmacologically blocked rats when the team activated the electronic device programmed to duplicate the memory-encoding function. The researchers went on to show that if a prosthetic device and its associated electrodes were implanted in animals with a normal, functioning hippocampus, the device could actually strengthen the memory being generated internally in the brain and enhance the memory capability of normal rats. "These integrated experimental modeling studies show for the first time that with sufficient information about the neural coding of memories, a neural prosthesis capable of real-time identification and manipulation of the encoding process can restore and even enhance cognitive mnemonic processes," says the paper. Next steps, according to Berger and Deadwyler, will be attempts to duplicate the rat results in primates (monkeys), with the aim of eventually creating prostheses that might help human victims of Alzheimer's disease, stroke, or injury recover function. Ref.: "A Cortical Neural Prosthesis for Restoring and Enhancing
thinkahol *

Does that hurt? Objective way to measure pain being developed - 0 views

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    ScienceDaily (Sep. 14, 2011) - Researchers from the Stanford University School of Medicine have taken a first step toward developing a diagnostic tool that could eliminate a major hurdle in pain medicine -- the dependency on self-reporting to measure the presence or absence of pain. The new tool would use patterns of brain activity to give an objective physiologic assessment of whether someone is in pain.
thinkahol *

TEDxRheinMain - Prof. Dr. Thomas Metzinger - The Ego Tunnel - YouTube - 1 views

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    Brain, bodily awareness, and the emergence of a conscious self: these entities and their relations are explored by Germanphilosopher and cognitive scientist Metzinger. Extensively working with neuroscientists he has come to the conclusion that, in fact, there is no such thing as a "self" -- that a "self" is simply the content of a model created by our brain - part of a virtual reality we create for ourselves. But if the self is not "real," he asks, why and how did it evolve? How does the brain construct the self? In a series of fascinating virtual reality experiments, Metzinger and his colleagues have attempted to create so-called "out-of-body experiences" in the lab, in order to explore these questions. As a philosopher, he offers a discussion of many of the latest results in robotics, neuroscience, dream and meditation research, and argues that the brain is much more powerful than we have ever imagined. He shows us, for example, that we now have the first machines that have developed an inner image of their own body -- and actually use this model to create intelligent behavior. In addition, studies exploring the connections between phantom limbs and the brain have shown us that even people born without arms or legs sometimes experience a sensation that they do in fact have limbs that are not there. Experiments like the "rubber-hand illusion" demonstrate how we can experience a fake hand as part of our self and even feel a sensation of touch on the phantom hand form the basis and testing ground for the idea that what we have called the "self" in the past is just the content of a transparent self-model in our brains. Now, as new ways of manipulating the conscious mind-brain appear on the scene, it will soon become possible to alter our subjective reality in an unprecedented manner. The cultural consequences of this, Metzinger claims, may be immense: we will need a new approach to ethics, and we will be forced to think about ourselves in a fundamentally new way. At
Janos Haits

geppetto - 0 views

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    Geppetto.org is a web-based multi-algorithm, multi-scale simulation platform engineered to support the simulation of complex biological systems and their surrounding environment. A completely modular platform. Engineered together with scientists, Geppetto lets you integrate different simulators and models. Independent modules allow the user to read different standard modeling formats and to simulate different aspects of reality. An open-source revolution. Geppetto is entirely open source and engineers, scientists and developers are welcome to contribute to its development by adding functionality to existing modules or by creating new ones!
oodlesai

Artificial Intelligence Development Company | AI Development Services - 0 views

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    Oodles Technologies specializes in providing various IT services with excellent results. The new dedicated services for Artificial Intelligence and its tools are no different than what we have done till now. With a revamped look and feel, Oodles AI brings every service in demand using Artificial Intelligence as a base under one roof. Our experts excel in developing solutions for a wide range of challenges using AI.
cdnsolutions

Mobility Solutions at MWC Americas 2017 San Francisco - 0 views

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    We are exhibitng in MWC Americas San Francisco to discuss on mobile technologies, outsourcing, IoT/M2M, application development services, mhealth, VOIP, etc. Meet us in South Hall, India Pavilion.
astrafizik

AI Evolution: Unraveling the Future of Artificial Intelligence - Astrafizik - 1 views

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    The field of artificial intelligence (AI) has experienced remarkable growth and development in recent years, pushing the boundaries of what was once thought possible. In this article, we'll explore the current state of AI evolution and where this fascinating field is heading in the future. We'll delve into various aspects of AI development, including machine learning, natural language processing, robotics, and AI ethics, as well as the role of quantum computing in AI's future.
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    AI Evolution: Unraveling the Future of Artificial Intelligence
Janos Haits

Vicarious - 0 views

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    "Vicarious is developing machine learning software based on the computational principles of the human brain. Our first technology is a visual perception system that interprets the contents of photographs and videos in a manner similar to humans. Powering this technology is a new computational paradigm we call the Recursive Cortical Network ™"
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    "Vicarious is developing machine learning software based on the computational principles of the human brain. Our first technology is a visual perception system that interprets the contents of photographs and videos in a manner similar to humans. Powering this technology is a new computational paradigm we call the Recursive Cortical Network ™"
thinkahol *

New Web Site Maps Endocrine Disruptors to Human Development: Scientific American - 0 views

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    A new interactive database, including a timeline showing how human fetuses develop, displays scientific data about controversial chemicals in a graphic way
thinkahol *

Most efficient quantum memory for light developed - 0 views

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    ScienceDaily (June 28, 2010) - An Australian National University-led team has developed the most efficient quantum memory for light in the world, taking us closer to a future of super-fast computers and communication secured by the laws of physics.
Skeptical Debunker

A mini-laboratory for all cases - Research News 03-2010-Topic 5 - Fraunhofer-Gesellschaft - 0 views

  •  »We’ll just have to wait for the results of the laboratory tests.« These words are familiar to many patients. It then usually takes several days for specimens to be sent to the laboratory and analyzed and for the doctor to receive the results. For many illnesses, however, a speedy diagnosis is crucial if the treatment is to be successful. In future, the patient might only have to sit in the waiting room for a few minutes until the results are ready. In a joint project, researchers from seven Fraunhofer institutes have developed a modular platform for in vitro diagnosis which enables various types of bioanalysis – of blood and saliva for example – to be conducted in the doctor’s surgery. »Thanks to its modular design our IVD platform is so flexible that it can be used for all possible bioanalytical tasks,« states Dr. Eva Ehrentreich-Förster from the Fraunhofer Institute for Biomedical Engineering (IBMT) in Potsdam-Golm.The core element of the mini-laboratory is a disposable cartridge made of plastic which can be fitted with various types of sensor. For an analysis the doctor fills the cartridge with reagents – binding agents which indicate the presence of certain substances such as antigens in the specimen material. Various tests or assays are available for different types of analysis. To perform an assay, the doctor only has to place the relevant substances in the cartridge and the test then takes place automatically. »We have optimized the assays so that up to 500 assay reactions can be conducted in parallel in a single analysis step,« explains Dr. Ehrentreich-Förster. Even in the case of complex analyses the doctor obtains a result within about 30 minutes. A new module on the reverse side of the cartridge also makes it possible to analyze the specimen material at DNA level.Once the cartridge has been prepared, the doctor places it in the measurement system. The results can be read out with either optical or electrochemical biosensors. The researchers have installed a readout window for both methods in the measurement system, which features a bypass through which the specimen is pumped.
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    Many illnesses can be reliably diagnosed through laboratory tests, but these in vitro analyses often use up valuable time. A system developed by Fraunhofer research scientists, which can carry out complex analyses on the spot, will soon be ready for the market.
Skeptical Debunker

Scientists find an equation for materials innovation - 0 views

  • By reworking a theory first proposed by physicists in the 1920s, the researchers discovered a new way to predict important characteristics of a new material before it's been created. The new formula allows computers to model the properties of a material up to 100,000 times faster than previously possible and vastly expands the range of properties scientists can study. "The equation scientists were using before was inefficient and consumed huge amounts of computing power, so we were limited to modeling only a few hundred atoms of a perfect material," said Emily Carter, the engineering professor who led the project. "But most materials aren't perfect," said Carter, the Arthur W. Marks '19 Professor of Mechanical and Aerospace Engineering and Applied and Computational Mathematics. "Important properties are actually determined by the flaws, but to understand those you need to look at thousands or tens of thousands of atoms so the defects are included. Using this new equation, we've been able to model up to a million atoms, so we get closer to the real properties of a substance." By offering a panoramic view of how substances behave in the real world, the theory gives scientists a tool for developing materials that can be used for designing new technologies. Car frames made from lighter, strong metal alloys, for instance, might make vehicles more energy efficient, and smaller, faster electronic devices might be produced using nanowires with diameters tens of thousands of times smaller than that of a human hair.
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    Princeton engineers have made a breakthrough in an 80-year-old quandary in quantum physics, paving the way for the development of new materials that could make electronic devices smaller and cars more energy efficient.
Walid Damouny

Key information about breast cancer risk and development is found in 'junk' DNA - 0 views

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    "A new genetic biomarker that indicates an increased risk for developing breast cancer can be found in an individual's "junk" (non-coding) DNA, according to a new study featuring work from researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues."
Charles Daney

Protein is linked to lung cancer development - 0 views

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    A protein that normally helps defend cells from infection can play a critical role in the development of lung cancer, according to MIT cancer biologists. Their findings suggest that the protein, NF-κB, could be a promising target for new drugs against lung cancer, which kills more than one million people each year.
Janos Haits

HTML - 0 views

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    "The Merobase Component Finder is a research project developed within the Software-Engineering Group at the University of Mannheim, Germany. "
Angel Scott

Top 12 Best Conferences on Banking & Finance - 0 views

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    Conferences provide best opportunities for the different areas delegates to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration. Conferences may be a fun way to learn things and are organized round the year for people to share their idea which they have developed on a particular topic and to get a hang about what others are working on. When it comes to learning about banking and finances, there are seldom better ways than visiting a conference on the same which are being held in various regions of the world. Just go through with our article; it'll help you more.
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    Conferences provide best opportunities for the different areas delegates to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration. Conferences may be a fun way to learn things and are organized round the year for people to share their idea which they have developed on a particular topic and to get a hang about what others are working on. When it comes to learning about banking and finances, there are seldom better ways than visiting a conference on the same which are being held in various regions of the world. Just go through with our article; it'll help you more.
cdnsolutions

Benefits of Laravel Framework in Web Application Development Infographic 2017 | Blog - 0 views

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    what is laravel 2017? Why choose laravel 2017? Features of laravel 2017? benefits of laravel 2017 ? This Infographic contain all the answer of these questions.
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