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"In short, this site is a record of my learning process as I try to understand aspects of colony health and productivity, and the reasons why various management techniques work (or don't). If you are a beginning beekeeper looking for basic information, or an experienced beekeeper looking for a summary of mite treatment options, I suggest that you go directly to Basic Beekeeping. I started keeping bees as a hobbyist in 1967, and then went on to get university degrees in biological sciences, specializing in entomology. In 1980 I began to build a migratory beekeeping operation in California, and currently run about 1000 hives with my two sons, from which we make our livings. In 1993, the varroa mite arrived in California, and after it wiped out my operation for the second time in 1999, I decided to "hit the books" and use my scientific background to learn to fight back"

Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.

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Roll over headlines to view top news summaries: Making Skinny Worms Fat and Fat Worms Skinny 'Exploratory' Butterflies Genetically Different Spiders Target Insects' Mate-Luring Signals Huge Natural Arch Found In Afghanistan Warm Water For Cold Winters in Northeast Ocean and River Water for Electricity Blood-Testing Device Can Spot Cancer, HIV Continuing Winter Ice Loss in Arctic Sea Plants Optimize Before Spinning Off New Species Hidden Code Reveals Brain Activity

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