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Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.

A giant asteroid smashing into Earth is the only plausible explanation for the extinction of the dinosaurs, a global scientific team said on Thursday, hoping to settle a row that has divided experts for decades. A panel of 41 scientists from across the world reviewed 20 years' worth of research to try to confirm the cause of the so-called Cretaceous-Tertiary (KT) extinction, which created a "hellish environment" around 65 million years ago and wiped out more than half of all species on the planet. Scientific opinion was split over whether the extinction was caused by an asteroid or by volcanic activity in the Deccan Traps in what is now India, where there were a series of super volcanic eruptions that lasted around 1.5 million years. The new study, conducted by scientists from Europe, the United States, Mexico, Canada and Japan and published in the journal Science, found that a 15-kilometre (9 miles) wide asteroid slamming into Earth at Chicxulub in what is now Mexico was the culprit. "We now have great confidence that an asteroid was the cause of the KT extinction. This triggered large-scale fires, earthquakes measuring more than 10 on the Richter scale, and continental landslides, which created tsunamis," said Joanna Morgan of Imperial College London, a co-author of the review.

the peer-reviewed open-access encyclopedia written by scholars from all around the world. Scholarpedia feels and looks like Wikipedia -- the free encyclopedia that anyone can edit. Indeed, both are powered by the same program -- MediaWiki. Both allow visitors to review and modify articles simply by clicking on the edit this article link.

Tom Clancy's The Division 2 - The Review Of New Ubisoft Title - Free APK Site

IJSTE Journal Publication & Peer Reviewed Journals in India. Research Scholar in all engineering and technology fields are swayed to help articles focused around late research.

"This research provides an understanding of the neural basis for social behavior from the perspective of how we evaluate social experiences and how our social interactions and decisions are motivated. We review research addressing the common neural systems underlying evaluation of social and nonsocial rewards. The human striatum, known to play a key role in reward processing, displays signals related to a broad spectrum of social functioning, including evaluating social rewards, making decisions influenced by social factors, learning about social others, cooperating, competing, and following social norms. WIREs Cogn Sci 2014, 5:61-73. doi: 10.1002/wcs.1266"

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For science researches and experiments, Mahendra Trivedi reviews are in plenty, Trivedi Science, to know more.

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Trivedi Foundation reviews can help you better understand about the organization and what are the opinions of people about it.

Trivedi Effect is a well-known phenomenon of transmitting Universal Intelligence power through the power of thoughts to create transformation.

"Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings. Delivering a comprehensive overview of the world's research output in   the fields of science, technology, medicine, social sciences, and arts   and humanities, Scopus features smart tools to track, analyze and   visualize research."

"In einer Kammer, kaum mehr als zwei mal drei Meter groß, einer früheren Toilette, findet man Lisa Thalheims Labor. Ein paar Meter weiter schrauben andere an Fahrrädern, Lisa Thalheim ist hier aber einem genetischen Fingerabdruck auf der Spur. Das Stadtbad Wedding ist einer der ersten Orte in Deutschland, an dem Autodidakten wie sie ihrer Liebe zur Gentechnik nachgehen können. "Software des Lebens" "Eine große Zukunft für die Biotechnologie-Industrie", hat der in Amerika als Naturwissenschafts-Papst verehrte Freeman Dyson vor fünf Jahren in der New York Review of Books vorhergesagt. Wenn sie dem Weg der Computerindustrie folge, "wenn sie klein und häuslich wird, statt groß und zentralisiert." Das scheint nun zu geschehen."

"Bislang hatte man eigentlich angenommen, dass die sexuelle Aktivität eher zunimmt, wenn der Mann im Haushalt hilft. Es kommt aber offenbar stark darauf an, welche Arbeiten er übernimmt - männliche oder "unmännliche". War die Aufgabenteilung klassisch - kümmerten sich die Männer also praktisch ausschließlich um Garten, Auto und Geld - hatten die Paare im Durchschnitt 1,6 Mal so häufig Sex wie Paare mit einer gerechteren Arbeitsteilung.... Sabino Kornrich (Juan March Institute, Madrid) et al.: American Sociological Review, doi: 10.1177/0003122412472340"

"Synthetic Biology promises low-cost, exponentially scalable products and global health solutions in the form of self-replicating organisms, or "living devices." As these promises are realized, proof-of-concept systems will gradually migrate from tightly regulated laboratory or industrial environments into private spaces as, for instance, probiotic health products, food, and even do-it-yourself bioengineered systems. What additional steps, if any, should be taken before releasing engineered self-replicating organisms into a broader user space? In this review, we explain how studies of genetically modified organisms lay groundwork for the future landscape of biosafety."

eLife is a researcher-driven initiative for the very best in science and science communication. We promote rapid, fair, and constructive review. We will use digital media and open access to increase the influence of published works. We commit to serving authors and advancing careers in science.

We develop scientific manuscripts to make the most of their science and help maximise their chances of publication in an influential journal.

Ancient History Encyclopedia is a non-profit community website that uses definitions, timelines, maps, illustrations, and articles to present ancient history in a very accessible way. The aim of this site is to promote ancient history, and to make it freely accessible for everybody. The website is built by the ancient history community, and every item is reviewed for quality.

The Library of Congress is launching a review of the bibliographic framework to better accommodate future needs. A major focus of the initiative will be to determine a transition path for the MARC 21 exchange format in order to reap the benefits of newer technology while preserving a robust data exchange that has supported resource sharing and cataloging cost savings in recent decades. This work will be carried out in consultation with the format's formal partners -- Library and Archives Canada and the British Library -- and informal partners -- the Deutsche Nationalbibliothek and other national libraries, the agencies that provide library services and products, the many MARC user institutions, and the MARC advisory committees such as the MARBI committee of ALA, the Canadian Committee on MARC, and the BIC Bibliographic Standards Group in the UK.