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The book is about networked science: the use of online tools to transform the way science is done. In the book I make the case that networked science has the potential to dramatically speed up the rate of scientific discovery, not just in one field, but across all of science. Furthermore, it won't just speed up discovery, but will actually amplify our collective intelligence, expanding the range of scientific problems which can be attacked at all. But, as I explain in the book, there are cultural obstacles that are blocking networked science from achieving its full potential. And so the book is also a manifesto, arguing that networked science must be open science if it is to realize its potential. Making the change to open science is a big challenge. In my opinion it's one of the biggest challenges our society faces, one that requires action on many fronts. One of those fronts is to make sure that everyone - including scientists, but also grant agencies, governments, libraries, and, especially, the general public -- understands how important the stakes are, and how urgent is the need for change.

The contamination and potential ecological risk posed by heavy metals from thirteen (13) sediment samples from different sampling sites along the lower portion of Agusan River were analyzed and assessed using different pollution indices. The results obtained shows that the total digest concentrations of different heavy metals under investigation have the following order: Cd < Pb < Zn < Mn, for both first sampling periods. The speciation and distribution pattern have shown that significant amounts of all metals are present in the residual fraction. Similarly, oxide-bound and organic-bound fractions were found to be highly important for Zn and Mn while Cd and Pb were significantly associated in the residual and exchangeable fractions. The results of different pollution indices moreover, showed that among all the heavy metals being studied, Cd posed the highest environmental risk across all sampling stations in both sampling periods and Mn metal was highly enriched and abundant in all of the sampling stations. Importantly, PCA results suggest that Zn, Mn and Pb may have the same origin while Cd might be coming from different sources, and this is corroborated well with the cluster analysis results. The results obtained from this work provide baseline data on the assessment of heavy metal pollution in the lower portion of Agusan River. Importantly, the acquired environmental indices will certainly help safety managers in assessing and interpreting the potential risk of the sediment associated chemical status that might adversely affect aquatic organisms in the selected sampling sites.

"Kathryn Taylor, associate professor in the Cancer Control Program, on conflicting advice about men getting tested for prostate cancer: "We tell men that there's no right or wrong answer [regarding prostate-specific antigen testing] at present, and it really comes down to a personal choice. And the onus, unfortunately, is on them to really educate themselves about the potential benefits as well as the potential harms." American Cancer Society Stands By Cancer Screening Guidelines October 22, 2009, MSN"

As we continue to carry around items that insist on requiring electricity to work, portable-even wearable-energy-generating systems are looking very attractive. A group of researchers has recently looked into the use of piezoelectric materials, which generate an electric field or potential when placed under mechanical stress. By placing these materials on a rubbery or flexible surface, they created a material that can generate the highest rate of energy conversion reported for similar systems. While these are still far from the market, the metrics of the flexible piezoelectrics so far are very promising.

"The same technology could potentially be used for bladder and multiple myeloma cancers, which also shed identifiable markers in urine. "Our goal is a device the size of a home pregnancy test priced around $10. Other prostate cancer tests coming to market cost up to $4,000 each. The UC Irvine team made price a key design factor of their work..The UC Irvine team developed a new type of sensor: They added nanoscale protein receptors to tiny, pencil-like viruses called phages that live only within bacteria. Double wrapping the phages with additional receptors greatly increases the capture and transmission of cancer molecule signals."

"uBiome is a citizen science project that allows the public access to cutting edge sequencing technology to understand their health through the microbiome. How does the microbiome affect my health? We are all covered in trillions of microbes -- in fact, they outnumber human cells 10:1. The trillions of bacteria live on and in us are collectively called the microbiome. Like the rainforest, the healthy human microbiome is a balanced ecosystem. The correct balance of microbes keeps potential pathogens in check and regulates our immune system. Microbes also perform essential functions such as digesting food and synthesizing vitamins. Studies have also linked the microbiome to human mood and behavior, as well as many gut disorders, eczema, and chronic sinusitis."

"A new bioprinter developed at a hackerspace can print living cells for less than the cost of an iPod touch. 3-D bioprinters have the potential to change the way medical research is conducted, even print living tissue and replacement organs, but they are expensive and highly specialized. They literally build living structures, like blood vessels or skin tissue, cell by cell, revolutionizing biomedical engineering. Unfortunately, they're expensive, rare, and require a Ph.D. (or two) to operate successfully. Frustrated by their cost and exclusivity, a group of makers at the DIYbio hackerspace BioCurious are developing a system open to anyone with a soldering iron and a serious passion for cell biology."

"We have sensitive body parts wired to the same area of the brain as rodents' fine-tuned whiskers. In people, "stimulating the fingers, lips or face in general could all have a similar effect," says UCI doctoral student Melissa Davis, co-author of the study, which appears in the June issue of PLoS ONE. "It's gender-neutral," adds co-author Ron Frostig, professor of neurobiology & behavior. He cautions that the research, funded by the National Institutes of Health, is a first step, albeit an important one.... "with the potential for maybe doing things before a victim even reaches the emergency room.""

"For 20 years, researchers have reported a potential link between gum disease and atherosclerotic heart disease from hardening of the arteries or stroke. "The message sent out by some in health-care professions, that heart attack and stroke are directly linked to gum disease, can distort the facts, alarm patients and perhaps shift the focus on prevention away from well-known risk factors for these diseases," said Dr. Peter Lockhart, a professor and chair of oral medicine at the Carolinas Medical Center in Charlotte, N.C. Lockhart wrote the heart group's new position statement in the journal Circulation. The statement was prepared after a three-year analysis of about 600 studies by an expert panel led by a dentist and a cardiologist."

SETILive is taking the Search for Extraterrestrial Intelligence (SETI) directly to you by presenting radio frequency signals LIVE from the SETI Institute's Allen Telescope Array (ATA) while it's pointed at stars that, based on Kepler exoplanet discoveries, have the best chances of being home to an alien civilization. We'll also be putting you "in the loop" where if enough of you see a potential extraterrestrial (ET) signal in the same data, then within minutes, the ATA will be interrupted and sent back to take a second look. The data you see will be from frequencies where human-made Radio Frequency Interference (RFI) crowds them and we believe the human eye will have a better chance than SETI's computer algorithms to find ET signals there.

If there is organic life deep under the ice on Europa, why would we need to disturb it at all? Potential source of unknown viruses etc. Risks of releasing something are low I guess, but the assumption that whatever may be there needs Earth-like conditions to survive and multiply is dangerous.

Our passion for developing e-learning material for the automotive sector allows us to realize the full potential of what computers and the Internet can achieve. The Electude team is driven by a vision that we must fundamentally change the way people acquire and retain knowledge and skills - by making it fun, effective and efficient.

""Experiments with amoebae that usually live as individuals but must also join with others to form multicellular bodies to complete their life cycles showed that cooperation depends on kinship. If amoebae occur in well-mixed cosmopolitan groups, then cheaters will always be able to thrive by freeloading on their cooperative neighbors. But if groups derive from a single cell, cheaters will usually occur in all-cheater groups and will have no cooperators to exploit. A multicellular body like the human body is an incredibly cooperative thing," Queller says, "and sociobiologists have learned that really cooperative things are hard to evolve because of the potential for cheating. "It's the single-cell bottleneck that generates high relatedness among the cells that, in turn, allows them to cooperate, " he says."

"Science is a scheme for thinking and solving issues using evidence. It requires hypotheses, i.e. potential truths that require examination. A hypothesis or scientific idea is only as strong as the evidence to support it. Strong evidence is predictive and reproducible, weak evidence is less so. Scientific thinking gives greater weight to the stronger evidence base."

"Sie haben auf der Haut von neun Stink-Frosch-Arten über 700 Substanzen identifiziert, die sich möglicherweise für die Entwicklung neuer Antibiotika eignen. Mit diesen antimikrobiellen Peptiden (AMPs) schützen die Frösche ihre Haut vor Infektionen. Das ist auch nötig, denn die Haut der kleinen Stinker ist immer feucht - in der tropischen Wärme ihrer südchinesischen Heimat wäre das ohne die Schutzsubstanzen ein fataler Nährboden für Bakterien. .. vielversprechend, da sie einen Zwei-Komponenten-Effekt aufweisen: Sie bekämpfen die Bakterien direkt und mobilisieren gleichzeitig das Immunsystem der Frösche, berichten die Wissenschaftler. Ein Antibiotikum mit diesen Eigenschaften wäre der Traum der Mediziner, denn viele krankheitserregende Bakterienarten werden zunehmend resistent gegen die gängigen Antibiotika. Die Forscher betonen, dass die Forschungsarbeiten noch am Anfang stehen, sie sind aber von dem enormen Potential der AMPs ihrer stinkenden Forschungsobjekte überzeugt"

The scientists were awarded the Nobel Prize for Physics in 2010 and graphene - the world's thinnest, strongest and most conductive material - is considered as having the potential to revolutionise materials science.

Warm, moist subsurface environment on Mars. Potential breeding ground for all sorts of things - first visitors will need to be very careful...

"Dr Zbinden said that while the discovery of the bacterium is no cause for alarm, it is important that it is recognised and the risk is quantified. "This bacterium seems to have a natural potential to cause severe disease and so it's important that clinicians and microbiologists are aware of it"

"Alternatively, the technique could potentially be used to insert cells directly into damaged retinas during ocular surgery, says Keith Martin, a professor of ophthalmology at the University of Cambridge, who led the research."

"For me, the picture that emerges is one in which chronic inflammation caused by poor oral health sets the stage for more serious illness. (See my earlier post for more info about the connection between inflammation and cancer.) I think further research will probably turn up some surprising connections between oral bacteria and cancer, but we don't have to wait for additional research to begin taking oral hygiene seriously as a potential way to head off cancer and CVD."