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Tonny Johnson

How to Identify Clinically Successful Biomarkers? - 0 views

The decisive goal of clinical biomarker discovery should be intended for developing high quality and low-cost disease detection/monitoring assays with high diagnostic accuracy. Innovative approache...

personalized biomarker personal diagnostics imaging biomarkers diagnostic tools molecular next generation sequencing clinical cancer clinically useful discovery viable successful validation of

started by Tonny Johnson on 01 Oct 12 no follow-up yet
thinkahol *

Super-high pressures used to create super battery: 'Most condensed form of energy stora... - 0 views

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    Using super-high pressures similar to those found deep in the Earth or on a giant planet, Washington State University researchers have created a compact, never-before-seen material capable of storing vast amounts of energy.
anonymous

Long Range Wifi Adapters and Antennas For Free Internet Access - 0 views

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    The best super long range WiFi antennas and high power wireless adapters for really long reaching wifi.
Walid Damouny

High levels of vitamin D in older people can reduce heart disease and diabetes - 0 views

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    "Middle aged and elderly people with high levels of vitamin D could reduce their chances of developing heart disease or diabetes by 43%, according to researchers at the University of Warwick."
thinkahol *

Theoretical breakthrough: Generating matter and antimatter from the vacuum | KurzweilAI - 0 views

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    Under just the right conditions-which involve an ultra-high-intensity laser beam and a two-mile-long particle accelerator-it could be possible to create something out of nothing, according to University of Michigan researchers.
Sonny Cher

Who Says Smoking Pot is Illegal? - 1 views

I have always been addicted to marijuana. It started out with my friends at high school, since then I cannot turn myself away from experiencing high times puffing marajuana. It feels so nice. Howev...

marajuana

started by Sonny Cher on 18 May 11 no follow-up yet
Sonny Cher

Energy Pills for Extra Energy - 3 views

I am always tired after working for the whole day. And my boyfriend is already mad at me because he felt neglected. I do not have time for him to go out on a date because I do not have the energy t...

legal highs

started by Sonny Cher on 02 May 11 no follow-up yet
thinkahol *

Stoner alert: McDonald's gets you legally high | KurzweilAI - 1 views

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    Fats in foods like potato chips and french fries make them nearly irresistible because they trigger natural marijuana-like chemicals in the body called endocannabinoids, researchers at the University of California, Irvine, have found. The researchers discovered that when rats tasted something fatty, cells in their upper gut started producing endocannabinoids, while sugars and proteins did not have this effect. How fats create, like, a buzz It starts on the tongue, where fats in food generate a signal that travels first to your brain, and then through a nerve bundle called the vagus to your intestines. There, the signal stimulates the production of endocannabinoids, which initiates a surge in cell signaling that prompts you to totally pig out - probably by initiating the release of digestive chemicals linked to hunger and satiety that compel us to eat more. And that leads to obesity, diabetes and cancer, the researchers said. But they suggest it might be possible to curb this process by obstructing endocannabinoid activity: for example, by using drugs that "clog" cannabinoid receptors. The trick: bypassing the brain to avoid creating anxiety and depression (which happens when endocannabinoid signaling is blocked in the brain). I'm guessing McDonald's won't be adding that drug to their fries. Ref.: Daniele Piomelli, et al., An endocannabinoid signal in the gut controls dietary fat intake, PNAS, 2011; in press
Erich Feldmeier

Tamir DI, Mitchell JP. Disclosing information about the self is intrinsically rewarding. - 0 views

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    Tamir DI, Mitchell JP. Disclosing information about the self is intrinsically rewarding. Department of Psychology, Harvard University, Cambridge, MA 02138, USA. dtamir@fas.harvard.edu Abstract Humans devote 30-40% of speech output solely to informing others of their own subjective experiences. What drives this propensity for disclosure? Here, we test recent theories that individuals place high subjective value on opportunities to communicate their thoughts and feelings to others and that doing so engages neural and cognitive mechanisms associated with reward. Five studies provided support for this hypothesis. Self-disclosure was strongly associated with increased activation in brain regions that form the mesolimbic dopamine system, including the nucleus accumbens and ventral tegmental area. Moreover, individuals were willing to forgo money to disclose about the self.
Janos Haits

CodeHS - 0 views

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    The Best Online Computer Science Class for High Schools.
Erich Feldmeier

Michael Lewis: Obama's Way | Vanity Fair, AUTOPILOT - 0 views

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    ""You'll see I wear only gray or blue suits," he said. "I'm trying to pare down decisions. I don't want to make decisions about what I'm eating or wearing. Because I have too many other decisions to make." He mentioned research that shows the simple act of making decisions degrades one's ability to make further decisions. It's why shopping is so exhausting. "You need to focus your decision-making energy. You need to routinize yourself. You can't be going through the day distracted by trivia." The self-discipline he believes is required to do the job well comes at a high price. "You can't wander around," he said. "It's much harder to be surprised. You don't have those moments of serendipity."
Janos Haits

LaTeX - A document preparation system - 0 views

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    LaTeX is a high-quality typesetting system; it includes features designed for the production of technical and scientific documentation. LaTeX is the de facto standard for the communication and publication of scientific documents. LaTeX is available as free software.
Dave James

Vital Tips That Help In Grabbing The Smart Option of Self Employed Loans Online! - 0 views

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    In the desperate financial situation, it is not at all wise to choose conventional lending because most of the high street lenders don't allow one to get small cash quickly.
Janos Haits

Free Online Textbooks, Flashcards, Adaptive Practice, Real World Examples, Simulations ... - 0 views

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    'Create a FREE CK-12 account to access more high quality resources, including our interactive Simulations and PLIX.'
Erich Feldmeier

Tung, Barreiro, Johnson, Gilad Social stress affects immune system gene expression in m... - 0 views

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    "Previous research on rhesus macaques discovered that social rank influenced components of the stress response, brain, and immune system. With gene chip technology for measuring the expression of over 6,000 different genes, Tung, Gilad and colleagues at Yerkes, Emory University, and Johns Hopkins looked for the first time in primates at the effects of social rank on genetic function. Comparing 49 different female monkeys of different rank revealed significant changes in the expression of 987 genes, including 112 genes associated with immune system function. The result fits with data in monkeys where low rank and chronic stress lead to compromised immune function, and, more loosely, with human studies linking low socioeconomic status and high social stress to elevated disease risk."
Erich Feldmeier

H. Takahashi et al. Think that's not fair? Your serotonin must be high. | The Scicuriou... - 0 views

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    "What they found here was a negative correlation. The MORE serotonin transporters you had, the less likely you were to reject unfair offers. The authors interpret this to mean that people with lower levels of serotonin transporter had a harsher sense of "fairness", than those with higher levels of serotonin transporter, and were more inclined to reject unfair offers. Why could this be the case? The authors looked at the personalities of the individuals. You might think that people with more aggressive personalities (or at least a tendency to get offended) might be more likely to reject unfair offers, but it turned out that this wasn't the case. Instead, it was people with more peaceful personalities, but stronger measures of trust, were more likely to reject the unfair offers. The authors believe that the people with higher trustfulness had higher standards of behavior, and thus were more likely to reject unfair offers, even if the rejected ended up badly for them"
Janos Haits

CHB - 0 views

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    Come work with us Interested in working with researchers from different disciplines within the Harvard, MIT and Broad community and an unique opportunity to participate in world-class research to make an impact on human health? Come work with us! We are looking for a computational biologists to handle data from a wide variety of experimental methods, focusing on next-gen sequencing technologies. Keep Reading...  SCDE is live The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue stem cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation. Keep Reading...  The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,
Erich Feldmeier

Noise and Signal - Nassim Taleb | Farnam Street - 0 views

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    "There is a biological story with information. I have been repeating that in a natural environment, a stressor is information. So too much information would be too much stress, exceeding the threshold of antifragility. In medicine, we are discovering the healing powers of fasting, as the avoidance of too much hormonal rushes that come with the ingestion of food. Hormones convey information to the different parts of our system and too much of it confuses our biology. Here again, as with the story of the news received at too high a frequency, too much information becomes harmful. And in Chapter x (on ethics) I will show how too much data (particularly when sterile) causes statistics to be completely meaningless. Now let's add the psychological to this: we are not made to understand the point, so we overreact emotionally to noise. The best solution is to only look at very large changes in data or conditions, never small ones"
Janos Haits

ATLAS Experiment - 0 views

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    ATLAS is a particle physics experiment at the Large Hadron Collider at CERN. The ATLAS detector is searching for new discoveries in the head-on collisions of protons of extraordinarily high energy. ATLAS will learn about the basic forces that have shaped our Universe since the beginning of time and that will determine its fate. Among the possible unknowns are the origin of mass, extra dimensions of space, unification of fundamental forces, and evidence for dark matter candidates in the Universe.
Erich Feldmeier

Strassmann & Queller: Close family ties keep cheaters in check: Why almost all multicel... - 0 views

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    ""Experiments with amoebae that usually live as individuals but must also join with others to form multicellular bodies to complete their life cycles showed that cooperation depends on kinship. If amoebae occur in well-mixed cosmopolitan groups, then cheaters will always be able to thrive by freeloading on their cooperative neighbors. But if groups derive from a single cell, cheaters will usually occur in all-cheater groups and will have no cooperators to exploit. A multicellular body like the human body is an incredibly cooperative thing," Queller says, "and sociobiologists have learned that really cooperative things are hard to evolve because of the potential for cheating. "It's the single-cell bottleneck that generates high relatedness among the cells that, in turn, allows them to cooperate, " he says."
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