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Skeptical Debunker

A mini-laboratory for all cases - Research News 03-2010-Topic 5 - Fraunhofer-Gesellschaft - 0 views

  •  »We’ll just have to wait for the results of the laboratory tests.« These words are familiar to many patients. It then usually takes several days for specimens to be sent to the laboratory and analyzed and for the doctor to receive the results. For many illnesses, however, a speedy diagnosis is crucial if the treatment is to be successful. In future, the patient might only have to sit in the waiting room for a few minutes until the results are ready. In a joint project, researchers from seven Fraunhofer institutes have developed a modular platform for in vitro diagnosis which enables various types of bioanalysis – of blood and saliva for example – to be conducted in the doctor’s surgery. »Thanks to its modular design our IVD platform is so flexible that it can be used for all possible bioanalytical tasks,« states Dr. Eva Ehrentreich-Förster from the Fraunhofer Institute for Biomedical Engineering (IBMT) in Potsdam-Golm.The core element of the mini-laboratory is a disposable cartridge made of plastic which can be fitted with various types of sensor. For an analysis the doctor fills the cartridge with reagents – binding agents which indicate the presence of certain substances such as antigens in the specimen material. Various tests or assays are available for different types of analysis. To perform an assay, the doctor only has to place the relevant substances in the cartridge and the test then takes place automatically. »We have optimized the assays so that up to 500 assay reactions can be conducted in parallel in a single analysis step,« explains Dr. Ehrentreich-Förster. Even in the case of complex analyses the doctor obtains a result within about 30 minutes. A new module on the reverse side of the cartridge also makes it possible to analyze the specimen material at DNA level.Once the cartridge has been prepared, the doctor places it in the measurement system. The results can be read out with either optical or electrochemical biosensors. The researchers have installed a readout window for both methods in the measurement system, which features a bypass through which the specimen is pumped.
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    Many illnesses can be reliably diagnosed through laboratory tests, but these in vitro analyses often use up valuable time. A system developed by Fraunhofer research scientists, which can carry out complex analyses on the spot, will soon be ready for the market.
Kane Nolan

tree doctor - 0 views

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    I have a number of trees at my farm house but because of some reason they started to dry fast. Thanks to Arbor Care, Inc. Because of you guys today my farm house looks alive. I must say that the team members of Arbor Care, Inc. are real tree doctors.
Erich Feldmeier

Naturopathic Diaries - Confessions of a Naturopathic Doctor - 0 views

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    "Britt Marie Hermes Former naturopathic doctor and "natural health expert." Current Master's of Science student in biomedicine. I share the hard truths about naturopathic education and practice to protect patients. Please don't be fooled by natural and alternative medicine. "
James Stewart

Thank Doctor Cleanduct for the Cleaner Air We Breathe - 2 views

I have a sister who is suffering from asthma. So when she visited my house she was so happy because she said she can breathe easily. So I told her it was because I had my HVAC system cleaned regula...

ducted heating cleaning

started by James Stewart on 22 Sep 11 no follow-up yet
Erich Feldmeier

Infusion of pseudo-poo cures gut infections in two women - Phenomena: Not Exactly Rocke... - 0 views

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    "People swap bacteria all the time-through sneezes and coughs, through hugs and sex, or through touching the same surfaces. Then there are people who swap bacteria because a doctor deliberately transplants faeces from one into the other. This isn't a bizarre medical perversion. It's usually a life-saving gambit. Faecal transplants-which are exactly what they sound like-are used to treat people who suffer from intense diarrhoea following rounds of antibiotics. The goal is simple: recalibrate the beneficial bacteria in a person's gut to fight off the ones that are causing them harm."
Erich Feldmeier

Ron Frostig, Melissa Davis Whisker stimulation prevents strokes in rats; Stimulating fi... - 0 views

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    "We have sensitive body parts wired to the same area of the brain as rodents' fine-tuned whiskers. In people, "stimulating the fingers, lips or face in general could all have a similar effect," says UCI doctoral student Melissa Davis, co-author of the study, which appears in the June issue of PLoS ONE. "It's gender-neutral," adds co-author Ron Frostig, professor of neurobiology & behavior. He cautions that the research, funded by the National Institutes of Health, is a first step, albeit an important one.... "with the potential for maybe doing things before a victim even reaches the emergency room.""
Janos Haits

MarilynMonrobot - 0 views

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    Heather is currently conducting her doctoral research at Carnegie Mellon's Robotics Institute and running Marilyn Monrobot Labs in NYC, which creates socially intelligent robot performances and sensor-based electronic art. Founder of the Robot Film Festival and Cyborg Cabaret, Heather was on the 2011 Forbes List for 30 under 30 in Science.
Erich Feldmeier

The Top 10 papers in Biological Sciences by Mendeley readership. - 0 views

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    William Gunn The Top 10 papers in Biological Sciences by Mendeley readership. With the Mendeley for Life Scientists webinar coming up on Thursday, I thought I would take a look at the readership stats for Biological Sciences. Biological Sciences has long been our biggest discipline, and having done my doctoral work in the Life Sciences, I knew this would be interesting. Overall, researchers in bioinformatics contributed most strongly to the most read papers, along with the older disciplines of micro- and molecular biology. Regardless of discipline, however, it's clear that the days of toiling away in isolation to thoroughly study one gene are over. Today, it's all about huge consortia and massive data. Here's what I found
Erich Feldmeier

Stanford Bioengineers Introduce 'Bi-Fi' - The Biological Internet | School of Engineering - 0 views

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    "If you were a bacterium, the virus M13 might seem innocuous enough. It insinuates more than it invades, setting up shop like a freeloading houseguest, not a killer. Once inside it makes itself at home, eating your food, texting indiscriminately. Recently, however, bioengineers at Stanford have given M13 a bit of a makeover. The researchers, Monica Ortiz, a doctoral candidate in bioengineering, and Drew Endy, PhD, an assistant professor of bioengineering, have parasitized the parasite and harnessed M13's key attributes - its non-lethality and its ability to package and broadcast arbitrary DNA strands - to create what might be termed the biological Internet, or "Bi-Fi." Their findings were published online Sept. 7 in the Journal of Biological Engineering."
Erich Feldmeier

@biogarage Traditional Chinese medicine #TCM origins: Mao invented it but didn't believ... - 0 views

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    "Mao's support of Chinese medicine was inspired by political necessity. In a 1950 speech (unwittingly echoed by the Senate's concerns about "providing health care to underserved populations"), he said: Our nation's health work teams are large. They have to concern themselves with over 500 million people [including the] young, old, and ill. … At present, doctors of Western medicine are few, and thus the broad masses of the people, and in particular the peasants, rely on Chinese medicine to treat illness. Therefore, we must strive for the complete unification of Chinese medicine"
thinkahol *

Interview with Matthieu Ricard | Taking Charge of Your Health - 0 views

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    "More than 35 years ago, Matthieu Ricard left a promising career in cellular genetics to study Buddhism in the Himalayas. After earning a doctorate in biology from the prestigious Pasteur Institute in France, Ricard left Paris and moved to Darjeeling, India to study with a great Tibetan master. Today, Ricard draws upon his recent writings, research into brain plasticity and cognitive neuropsychology, and his work with neuroscientists and Buddhist practitioners at the Mind and Life Institute (co-founded by the Dalai Lama), while examining the interconnecting relationship between meditation, brain circuitry, and emotional balance."
thinkahol *

Lies, Damned Lies, and Medical Science - Magazine - The Atlantic - 0 views

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    Much of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong. So why are doctors-to a striking extent-still drawing upon misinformation in their everyday practice? Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science. 
Skeptical Debunker

Controversial Studies Trigger Dropoff in Osteoporosis Treatment - 0 views

  • The North American Spine Society and the Society of Interventional Radiology have pointed to flaws in both studies. And earlier studies, published over 15 years, found major benefits to kyphoplasty and a related procedure called vertebroplasty. "We're missing opportunities for patients to receive a safe and effective treatment that can significantly reduce their pain and disability," said Malamis, an interventional radiologist. The procedures are used to treat vertebral compression fractures in patients with osteoporosis and other conditions that result in brittle bones. In a vertebroplasty, an acrylic cement is injected into a fractured vertebra. In a kyphoplasty, a balloon-tipped catheter first is inserted into the fracture. The balloon is inflated to restore the height and shape of the vertebra before the cement is injected. Neva Nelson, 74, of Naperville, Ill., said a kyphoplasty that Malamis performed in October, 2009, has greatly reduced her pain in a vertebra in her lower back that she fractured after falling on ice. Before her kyphoplasty, Nelson had to sit on cushions. Walking, and especially standing, were painful. "I had to do something," she said. "I could not go on like that." Nelson said that since undergoing her kyphoplasty, "I don't have to worry about my back any more." In the controversial studies, patients were randomly assigned to receive a vertebroplasty or a placebo-like "sham" procedure. In the sham procedure, patients received an injection of anesthetic, but no cement. However, patients in severe pain are reluctant to enroll in a trial where there's a 50 percent chance of receiving a sham treatment. In one of the studies, researchers had to screen 1,813 patients to enroll just 131 subjects. In the other study, only 78 of 219 eligible patients were enrolled. This low enrollment rate raises the possibility that the patients who did enroll were not representative. Patients experience the greatest pain during the first three months after a compression fracture. Thereafter, pain gradually subsides. Thus, a vertebroplasty or kyphoplasty provides the greatest benefit when performed within a week or two of the fracture. But the studies enrolled patients up to 12 months after fractures. In addition to reducing pain and disability, a kyphoplasty can reduce the risk of subsequent fractures by improving the angle and height of the spine. The studies evaluated vertebroplasty alone, and did not include the more innovative and very different kyphoplasty procedure. Malamis suggests the medical community wait for the results of additional studies now underway before passing final judgment on vertebroplasty or kyphoplasty. In the mean time, he notes that Medicare still covers the procedures.
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    Dr. Angelo Malamis says that 90 percent of his patients who have undergone a treatment called balloon kyphoplasty for vertebral fractures report significant reductions in pain and disability. But the number of kyphoplasty referrals Malamis has received from primary care doctors has dropped sharply since two controversial studies were published last year in the New England Journal of Medicine. In findings that have been disputed by two medical societies, researchers reported that a procedure related to kyphoplasty was not significantly better than a placebo-like procedure in reducing pain and disability.
thinkahol *

It's not an apple a day after all -- it's strawberries: Flavonoids could represent two-... - 1 views

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    ScienceDaily (June 28, 2011) - A recent study from scientists at the Salk Institute for Biological Studies suggests that a strawberry a day (or more accurately, 37 of them) could keep not just one doctor away, but an entire fleet of them, including the neurologist, the endocrinologist, and maybe even the oncologist.
anonymous

Enhance The Profit From Your Dairy Farm! - 1 views

Dairy farming is one of the most successful and ever in demand business which needs concentration over a long-term production of milk. The dairy farmers all around the world work hard each day to s...

dairy farming milk production increase supply Mahendra Trivedi Effect Science research

started by anonymous on 26 Dec 14 no follow-up yet
John Gray

5thAnnual Operating Theatre Management Conference - 0 views

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    Browse Operating Theatre Techs/Anaesthetic Techs/ODPs/CSSD jobs on Medepage. Australia's leading Careers site for Nurses, Doctors & Australian Health Care professionals...
Skeptical Debunker

Research: How you think about your age may affect how you age - 0 views

  • "How old you are matters, but beyond that it's your interpretation that has far-reaching implications for the process of aging," said Markus H. Schafer, a doctoral student in sociology and gerontology who led the study. "So, if you feel old beyond your own chronological years you are probably going to experience a lot of the downsides that we associate with aging. "But if you are older and maintain a sense of being younger, then that gives you an edge in maintaining a lot of the abilities you prize." Schafer and co-author Tetyana P. Shippee, a Purdue graduate who is a research associate at Purdue's Center on Aging and the Life Course, compared people's chronological age and their subjective age to determine which one has a greater influence on cognitive abilities during older adulthood. Nearly 500 people ages 55-74 were surveyed about aging in 1995 and 2005 as part of the National Survey of Midlife Development in the United States. In 1995, when people were asked what age do you feel most of the time, the majority identified with being 12 years younger than they actually were. "We found that these people who felt young for their age were more likely to have greater confidence about their cognitive abilities a decade later," Schafer said. "Yes, chronological age was important, but the subjective age had a stronger effect. "What we are not sure about is what comes first. Does a person's wellness and happiness affect their cognitive abilities or does a person's cognitive ability contribute to their sense of wellness. We are planning to address this in a future study."
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    The saying "You're only as old as you feel" really seems to resonate with older adults, according to research from Purdue University.
Skeptical Debunker

Human cells exhibit foraging behavior like amoebae and bacteria - 0 views

  • "As far as we can tell, this is the first time this type of behavior has been reported in cells that are part of a larger organism," says Peter T. Cummings, John R. Hall Professor of Chemical Engineering, who directed the study that is described in the March 10 issue of the Public Library of Science journal PLoS ONE. The discovery was the unanticipated result of a study the Cummings group conducted to test the hypothesis that the freedom with which different cancer cells move - a concept called motility - could be correlated with their aggressiveness: That is, the faster a given type of cancer cell can move through the body the more aggressive it is. "Our results refute that hypothesis—the correlation between motility and aggressiveness that we found among three different types of cancer cells was very weak," Cummings says. "In the process, however, we began noticing that the cell movements were unexpectedly complicated." Then the researchers' interest was piqued by a paper that appeared in the February 2008 issue of the journal Nature titled, "Scaling laws of marine predator search behaviour." The paper contained an analysis of the movements of a variety of radio-tagged marine predators, including sharks, sea turtles and penguins. The authors found that the predators used a foraging strategy very close to a specialized random walk pattern, called a Lévy walk, an optimal method for searching complex landscapes. At the end of the paper's abstract they wrote, "...Lévy-like behaviour seems to be widespread among diverse organisms, from microbes to humans, as a 'rule' that evolved in response to patchy resource distributions." This gave Cummings and his colleagues a new perspective on the cell movements that they were observing in the microscope. They adopted the basic assumption that when mammalian cells migrate they face problems, such as efficiently finding randomly distributed targets like nutrients and growth factors, that are analogous to those faced by single-celled organisms foraging for food. With this perspective in mind, Alka Potdar, now a post-doctoral fellow at Case Western Reserve University and the Cleveland Clinic, cultured cells from three human mammary epithelial cell lines on two-dimensional plastic plates and tracked the cell motions for two-hour periods in a "random migration" environment free of any directional chemical signals. Epithelial cells are found throughout the body lining organs and covering external surfaces. They move relatively slowly, at about a micron per minute which corresponds to two thousandths of an inch per hour. When Potdar carefully analyzed these cell movements, she found that they all followed the same pattern. However, it was not the Lévy walk that they expected, but a closely related search pattern called a bimodal correlated random walk (BCRW). This is a two-phase movement: a run phase in which the cell travels primarily in one direction and a re-orientation phase in which it stays in place and reorganizes itself internally to move in a new direction. In subsequent studies, currently in press, the researchers have found that several other cell types (social amoeba, neutrophils, fibrosarcoma) also follow the same pattern in random migration conditions. They have also found that the cells continue to follow this same basic pattern when a directional chemical signal is added, but the length of their runs are varied and the range of directions they follow are narrowed giving them a net movement in the direction indicated by the signal.
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    When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found. The discovery has a practical value for drug development: Incorporating this basic behavior into computer simulations of biological processes that involve cell migration, such as embryo development, bone remodeling, wound healing, infection and tumor growth, should improve the accuracy with which these models can predict the effectiveness of untested therapies for related disorders, the researchers say.
Pamela Saunders

International Stem Cell Corporation Congratulates Sweden's Karolinska University Hospit... - 6 views

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    International Stem Cell Corporation (ISCO) applauds the recent announcement by doctors at Sweden's Karolinska University Hospital on the creation of the world's first artificial trachea; ISCO would like our followers to understand that the concept of growing cells on a scaffold to treat diseases is showing success in our own research as exemplified by the following: 1) Collaboration with Cytograft in growing artificial blood vessels for treatment of lower limb ischemia.
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