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Erich Feldmeier

Fred H. Gage and Alysson R. Muotri Jumping Genes in the Brain Ensure That Even Identica... - 0 views

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    "So-called jumping genes, segments of DNA that can copy and paste them­selves into new places in the genome, can alter the activity of full-length genes. Occasionally they will turn on neighboring genes in these locations. That activity occurs more in the brain than other areas, resulting in different traits and behaviors, even in closely related individuals. These mobile genetic elements may also turn out to play a role in people's disposition to psychiatric disorders"
Janos Haits

UCSC Genomics Text Indexing - 0 views

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    UCSC Genome Bioinformatics Genocoding Project Genomic Text Indexing: Scanning papers for genomic identifiers and mapping them to the human genome. We currently recognize DNA and protein sequences, SNPs, bands and gene symbols.
Erich Feldmeier

Dennis Kasper: Für ein gesundes Immunsystem: Microbiom Jedem seine Darmkeime ... - 0 views

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    "Was die Zellzahl angeht, besteht jeder Mensch zu 90 Prozent aus Mikroben", sagt Dennis Kasper von der Harvard Medical School in Boston. Die Hauptmasse dieser Mitbewohner des menschlichen Körpers lebt im Darm. Sie unterstützen nicht nur die Verdauung, sondern sind für unsere Gesundheit generell unverzichtbar. So wie sie sich speziell an ihren Wirt angepasst haben, hat sich auch unser Organismus an die Mikroben angepasst. Insbesondere hängt die normale Entwicklung des Immunsystems von der Mitwirkung der Darmkeime ab. Das schließen Kasper und seine Kollegen aus ihren Experimenten mit Mäusen, die in keimfreier Umgebung gehalten wurden. In den bakterienfreien Darm neugeborener Mäuse übertrugen die Forscher ein natürliches Gemisch von Darmmikroben, das entweder von gesunden Mäusen oder von gesunden Menschen stammte. In beiden Fällen kam es zum Wachstum von Bakterien in ähnlich hoher Zahl und mit einem ähnlich breiten Artenspektrum. Beide Bakterienpopulationen waren aber aus sehr unterschiedlichen Keimspezies zusammengesetzt, wie DNA-Analysen zeigten. Die Untersuchung von Darmlymphknoten ergab, dass sich bei den Mäusen mit den „menschlichen" Darmkeimen genauso wenige Immunzellen entwickelt hatten wie bei Mäusen, deren Darm völlig keimfrei blieb. „Es schien so, als ob diese Mäuse die Bakterien gar nicht erkennen würden", sagt Hachung Chung, ein Mitglied des Forscherteams"
Janos Haits

ENCODE Project at UCSC - 0 views

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    The Encyclopedia of DNA Elements (ENCODE) Consortium is an international collaboration of research groups funded by the National Human Genome Research Institute (NHGRI). The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active.
Erich Feldmeier

Hug the Monkey, Oxytocin and others - 0 views

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    "Empathy Linked to Gene -- and We Can Tell Variations in the genes for oxytocin receptors may influence empathy -- and we can tell who's got them in 20 seconds. In the study, by Aleksandr Kogan of UC Berkeley, 24 couples provided DNA samples and then the couples recounted to each other a time when they had suffered. The conversations were videotaped. Then, observers wached 20-second segments of the videos and were asked to rate each person as kind, trustworthy and compassionate. The observers tended to pick the people in the couples who had a variation in the oxytocin receptor gene known as the GG genotype. It's interesting enough that empathy might be linked to variations in our genes. And also interesting that we humans are so exquisitely sensitive to social cues that we can easily and quickly pick this out."
Erich Feldmeier

Stanford Bioengineers Introduce 'Bi-Fi' - The Biological Internet | School of Engineering - 0 views

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    "If you were a bacterium, the virus M13 might seem innocuous enough. It insinuates more than it invades, setting up shop like a freeloading houseguest, not a killer. Once inside it makes itself at home, eating your food, texting indiscriminately. Recently, however, bioengineers at Stanford have given M13 a bit of a makeover. The researchers, Monica Ortiz, a doctoral candidate in bioengineering, and Drew Endy, PhD, an assistant professor of bioengineering, have parasitized the parasite and harnessed M13's key attributes - its non-lethality and its ability to package and broadcast arbitrary DNA strands - to create what might be termed the biological Internet, or "Bi-Fi." Their findings were published online Sept. 7 in the Journal of Biological Engineering."
Erich Feldmeier

@biogarage #gender Macht Arbeitslosigkeit /Männer/ alt? - @bdw-redaktion - 0 views

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    "Die Forscher haben für ihre Studie die Länge der Telomere von 5.620 finnischen Frauen und Männern des Jahrgangs 1966 untersucht. Neben DNA-Proben hatten diese Personen auch Informationen über ihre Beschäftigungsverhältnisse abgegeben und ob und wie lange sie einmal arbeitslos gewesen waren. Die Auswertungen zeigten: Männer, die mindestens zwei Jahre lang arbeitslos gewesen waren, hatten doppelt so häufig signifikant verkürzte Teleomere als Männer, die durchwegs in Beschäftigung gewesen waren. Die Ergebnisse hielten auch statistischen Verfahren stand, die systematisch andere Faktoren ausschließen, die zu dem Ergebnis geführt haben könnten - beispielsweise der Gesundheitszustand, oder sozioökonomische Faktoren. Die Forscher fanden den Zusammenhang zwischen verkürzten Telomeren und Arbeitslosigkeit allerdings nicht bei den Frauen. Warum das so ist, bleibt unklar"
Ivan Pavlov

Skeletal remains of 24,000-year-old boy raise new questions about first Americans - 0 views

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    Results from a DNA study of a young boy's skeletal remains believed to be 24,000 years old could turn the archaeological world upside down -- it's been demonstrated that nearly 30 percent of modern Native American's ancestry came from this youngster's gene pool, suggesting First Americans came directly from Siberia, according to a research team that includes a Texas A&M University professor.
Erich Feldmeier

Genome Alberta | Genomics Blog | Biohacking 101: Tools of the Biopunk Trade - 0 views

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    "Cathal Garvey demonstrating Do-it-Yourself DNA extraction in a tent from smarimc on Vimeo. Biohackers, like computer hackers before them, need little more than an electronic mailing list to trade tips and information and find the tools they need. DIYbio is by far the largest such list."
Erich Feldmeier

@biogarage Project Biolab Prague CZ [brmlab] - 0 views

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    "The aim of the project is to get acquainted with usually inaccessible laboratory procedures - extraction of various organic substances and study them further, growing bacteria on agar plates, DNA extraction and sequencing, explant cultures, various behavioral studies (see BrmRat ) and even heredity experiments. A lot of this may be simple stuff you do not need a well-equipped lab for - once we understand the principles, we can make our way forward. Goals The goal of this project is mainly to enable access to experimental biology for everyone interested in it"
Barry mahfood

THE PRICE OF RICE - Singularity in Bite-Sized Bits: The Transformative Power of Self-Re... - 0 views

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    Consider the power of self-replication. Biological systems are all products of self-replication, from the very first bit of self-replicating DNA, down through billions of years, entwined in every branch of the tree of life and our own DNA.
Ciencias diferentenet.com

>> O DNA vai a escola - 0 views

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    Sitio com animações, experiências e ligações interessantes sobre ADN.
The Ravine / Joseph Dunphy

Self-Replicating Chemicals Evolve Into Lifelike Ecosystem | Wired Science from Wired.com - 0 views

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    Researchers attempting to create something reminiscent the earliest life, based on RNA instead of DNA, achieve a success.
Mike Chelen

RNA world easier to make : Nature News - 0 views

  • John Sutherland and his colleagues from the University of Manchester, UK
  • ribonucleotide
  • building block of RNA
  • ...29 more annotations...
  • Donna Blackmond, a chemist at Imperial College London.
  • strong evidence for the RNA world
  • 'RNA world' hypothesis, which suggests that life began when RNA, a polymer related to DNA that can duplicate itself and catalyse reactions
  • chemists had thought the subunits would probably assemble themselves first, then join to form a ribonucleotide
  • three distinct parts: a ribose sugar, a phosphate group and a base
  • RNA polymer is a string of ribonucleotides
  • efforts to connect ribose and base together have met with frustrating failure
  • researchers have now managed to synthesise
  • ribonucleotides
  • remedy is to avoid producing separate ribose-sugar and base subunits
  • makes a molecule whose scaffolding contains a bond that will
  • be the key ribose-base connection
  • atoms are then added around this skeleton
  • final connection is to add a phosphate group
  • influences the entire synthesis
  • acting as a catalyst, it guides small organic molecules into making the right connections
  • What we have ended up with is molecular choreography
  • objectors to the RNA-world theory say the RNA molecule as a whole is too complex to be created using early-Earth geochemistry
  • flaw is in the logic — that this experimental control by researchers in a modern laboratory could have been available on the early Earth
  • Robert Shapiro, a chemist at New York University
  • early-Earth scenarios
  • heating molecules in water, evaporating them and irradiating them with ultraviolet light
  • results showing that they can string nucleotides together
  • ultimate goal is to get a living system (RNA) emerging from a one-pot experiment
  • need to know what the constraints on the conditions are first
  • Shapiro sides with
  • another theory of life's origins
  • because RNA is too complex to emerge from small molecules, simpler metabolic processes
  • eventually catalysed the formation of RNA and DNA
Charles Daney

Genes That Make Us Human -- ScienceNOW - 0 views

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    Finding genes that have evolved in humans among our genome's 3 billion bases is no easy feat. But now, a team has pinpointed three genes that arose from noncoding DNA and may help make our species unique.
Charles Daney

Understanding Cancer Part 2 - Telomerase, the Road to Immortality, and the Nobel Prize - 0 views

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    Telomeres are necessary for several reasons, among them to act as 'padding' during cell duplication. Every time a linear DNA molecule is replicated it loses a few base pairs from the ends (the reason why is quite interesting,
Charles Daney

Understanding Cancer Part 2 - Telomerase, the Road to Immortality, and the Nobel Prize ... - 0 views

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    Telomeres are necessary for several reasons, among them to act as 'padding' during cell duplication. Every time a linear DNA molecule is replicated it loses a few base pairs from the ends (the reason why is quite interesting,
anonymous

Klebsiella Pneumoniae Experiment - Trivedi Science - 0 views

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    Trivedi Science - Solation of genomic DNA from Klebsiella pneumonia (ATCC 15380) samples, generating RAPD-Fingerprinting profiles showing Polymorphic bands with five RAPD primers
anonymous

The Trivedi Effect - Crop and Plant Genetic Reports - 0 views

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    Crop and plant genetic reports reflect the drastic improvements with The Trivedi Effect in DNA mapping for 38 varieties of crop carried out by Bangalore Genei.
anonymous

Vibrio Parahaemolyticus Test and Experiment - Mahendra Trivedi - 0 views

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    Vibrio Parahaemolyticus - Genomic DNA was isolated from the pure culture pellet provided by Medical Research Centre- (Mumbai), on behalf of Mahendra Trivedi.
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