Group items tagged

(PhysOrg.com) -- The fact that our female ancestors dispersed more than our male ancestors can lead to conflicts within the brain that influence our social behaviour, new research reveals.

Three Harvard scholars trained in chemistry and physics pursue innovative approaches and tools that address problems in neuroscience.

UCLA and University of Pittsburgh researchers found that obese people had 8 percent less brain tissue than people with normal weight, while overweight people had 4 percent less tissue in their frontal lobes.

Neuroscientists are mapping out a complete atlas of connectivity in the human brain, but what's emerging is a battle of scales.

In the first clinical proof of its kind, a drug has dramatically shrunk cancerous tumors by disrupting a key genetic pathway. But a study targeting one deadly brain cancer, medulloblastoma, ended in disappointment as the patient's once-tamed tumor quickly developed resistance to the drug and killed him.

Have a friend remove an object from a room you know well--say, a napkin holder from your kitchen--and then see if you can guess what he's taken away. Even if you don't know the answer, your eyes will unconsciously fixate on the stretch of countertop next to the toaster where the holder usually sits. Remembering what goes where in your kitchen is called relational memory, and now scientists have shown that your unknowing stare may be a sign that your brain remembers even when you don't.

Neuroscientists explore the mind's sexual side and discover that desire is not quite what we thought it was.

"In the study, researchers took two groups of healthy young adults. Each group completed two learning sessions. The difference was that between the first and second sessions, one group got to take a 90-minute nap. The group that got the nap improved in their ability to learn by 10 percent, while the non-napping group did 10 percent worse."

For theoretical neurobiologist and author Mark Changizi, "why" has always been more interesting than "how." While many scientists focus on the mechanics of how we do what we do, his research aims to grasp the ultimate foundations underlying why we think, feel and see as we do. Guided by this philosophy, he has made important discoveries on why we see in color, why we see illusions, why we have forward-facing eyes, why letters are shaped as they are, why the brain is organized as it is, why animals have as many limbs and fingers as they do, and why the dictionary is organized as it is.

"The timing of umbilical cord clamping at birth should be delayed just a few minutes longer, suggest researchers at the University of South Florida's Center of Excellence for Aging and Brain Repair."

ScienceDaily (Jan. 12, 2011) - Scientists have found that the pleasurable experience of listening to music releases dopamine, a neurotransmitter in the brain important for more tangible pleasures associated with rewards such as food, drugs and sex. The new study from The Montreal Neurological Institute and Hospital -- The Neuro at McGill University also reveals that even the anticipation of pleasurable music induces dopamine release [as is the case with food, drug, and sex cues]. Published in the journal Nature Neuroscience, the results suggest why music, which has no obvious survival value, is so significant across human society.

That's how it is with the early flickers of paranoia, confusion, hypersensitivity and hallucination in people who develop schizophrenia. They often emerge exactly when adolescence is throwing the body and brain for a loop, and years before the disease manifests itself fully.

ScienceDaily (May 13, 2011) - Parents know the unparalleled joy and wonder of hearing a beloved child's first words turn quickly into whole sentences and then babbling paragraphs. But how human children acquire language-which is so complex and has so many variations-remains largely a mystery. Fifty years ago, linguist and philosopher Noam Chomsky proposed an answer: Humans are able to learn language so quickly because some knowledge of grammar is hardwired into our brains. In other words, we know some of the most fundamental things about human language unconsciously at birth, without ever being taught.

Theodore Berger and his team at the USC Viterbi School of Engineering's Department of Biomedical Engineering have developed a neural prosthesis for rats that is able to restore their ability to form long-term memories after they had been pharmacologically blocked. In a dramatic demonstration, Berger blocked the ability to rats to form long-term memories by using pharmacological agents to disrupt the neural circuitry that communicates between two subregions of the hippocampus, CA1 and CA3, which interact to create long-term memory, prior research has shown. The rats were unable to remember which lever to pull to gain a reward, or could only remember for 5-10 seconds, when previously they could remember for a long period of time. The researchers then developed an artificial hippocampal system that could duplicate the pattern of interaction between CA3-CA1 interactions. Long-term memory capability returned to the pharmacologically blocked rats when the team activated the electronic device programmed to duplicate the memory-encoding function. The researchers went on to show that if a prosthetic device and its associated electrodes were implanted in animals with a normal, functioning hippocampus, the device could actually strengthen the memory being generated internally in the brain and enhance the memory capability of normal rats. "These integrated experimental modeling studies show for the first time that with sufficient information about the neural coding of memories, a neural prosthesis capable of real-time identification and manipulation of the encoding process can restore and even enhance cognitive mnemonic processes," says the paper. Next steps, according to Berger and Deadwyler, will be attempts to duplicate the rat results in primates (monkeys), with the aim of eventually creating prostheses that might help human victims of Alzheimer's disease, stroke, or injury recover function. Ref.: "A Cortical Neural Prosthesis for Restoring and Enhancing

ScienceDaily (July 28, 2011) - The human brain is the most complex of all organs, containing billions of neurons with their corresponding projections, all woven together in a highly complex, three-dimensional web. To date, mapping this vast network posed a practically insurmountable challenge to scientists. Now, however, a research team from the Heidelberg-based Max Planck Institute for Medical Research has developed a method for tackling the mammoth task. Using two new computer programs, KNOSSOS and RESCOP, a group of over 70 students mapped a network of more than 100 neurons -- and they did so faster and more accurately than with previous methods.

ScienceDaily (Sep. 14, 2011) - Researchers from the Stanford University School of Medicine have taken a first step toward developing a diagnostic tool that could eliminate a major hurdle in pain medicine -- the dependency on self-reporting to measure the presence or absence of pain. The new tool would use patterns of brain activity to give an objective physiologic assessment of whether someone is in pain.

"Tracking and understanding the complex connections within the brain may finally reveal the neural secret of cognitive ability."