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That's how it is with the early flickers of paranoia, confusion, hypersensitivity and hallucination in people who develop schizophrenia. They often emerge exactly when adolescence is throwing the body and brain for a loop, and years before the disease manifests itself fully.

"Johns Hopkins University scientists trying to determine why people develop serious mental illness are focusing on an unlikely factor: a common parasite spread by cats."

Some argue that these genes bring benefits - mental illness and genius have a long-standing link - but archaeologist Penny Spikins at the University of York, UK, goes further. She believes that mental illness and conditions such as autism persist at such high levels because in the past they were advantageous to humanity. "I think that part of the reason Homo sapiens were so successful is because they were willing to include people with different minds in their society - people with autism or schizophrenia, for example."

A new new brain imaging system that can identify a subject's simple thoughts may lead to clearer diagnoses for Alzheimer's disease or schizophrenia - as well as possibly paving the way for reading people's minds. Michael Greicius at Stanford University in California and colleagues used functional magnetic resonance imaging (fMRI) to identify patterns of brain activity associated with different mental states. He asked 14 volunteers to do one of four tasks: sing songs silently to themselves; recall the events of the day; count backwards in threes; or simply relax. Participants were given a 10-minute period during which they had to do this. For the rest of that time they were free to think about whatever they liked. The participants' brains were scanned for the entire 10 minutes, and the patterns of connectivity associated with each task were teased out by computer algorithms that compared scans from several volunteers doing the same task. This differs from previous experiments, in which the subjects were required to perform mental activities at specific times and the scans were then compared with brain activity when they were at rest. Greicius reasons his method encourages "natural" brain activity more like that which occurs in normal thought.