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thinkahol *

BBC News - Animal's genetic code redesigned - 1 views

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    Researchers say they have created the first ever animal with artificial information in its genetic code.
jacob logan

Genetic test could enable new targeted prostate cancer therapy - 1 views

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    A new study by The Institute of Cancer Research, London (ICR) has shown that a genetic test for faults in DNA repair could enable targeted nuclear treatments for patients with prostate cancer.
Janos Haits

CHB - 0 views

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    Come work with us Interested in working with researchers from different disciplines within the Harvard, MIT and Broad community and an unique opportunity to participate in world-class research to make an impact on human health? Come work with us! We are looking for a computational biologists to handle data from a wide variety of experimental methods, focusing on next-gen sequencing technologies. Keep Reading...  SCDE is live The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue stem cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation. Keep Reading...  The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,
anonymous

Microbial Genetics Report: Trivedi Science - 0 views

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    Get bacterial identification report based on 16S rDNA data at the Trivedi Science.
anonymous

How To Produce More Mangoes With Seed Technology - 1 views

Agriculture has been considered as a foundation for life. A number of agricultural methods and technology have adopted in recent years to enhance crop production. New methods of farming were discov...

seed science and technology mango production

started by anonymous on 10 Jan 15 no follow-up yet
anonymous

Growing Mustard: A Beginners Guide for Commercial Production - 1 views

Mustard is a common spice grown in Indian sub-continent and is used for garnishing various dishes. The plant bears seeds that are processed into dry seeds for garnishing or crushed to extract musta...

mustard seeds plants growing sustainable farming industrial agriculture organic The Trivedi Effect

started by anonymous on 25 Dec 14 no follow-up yet
Nits Mahajan

Take Advantage Of Clinical Genomics Market - Read This Research Report By World Researc... - 0 views

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    Clinical Genomics Market By Test Type (Diagnostic, Genetic, Newborn Screening, Prenatal, Carrier Screening), Software, Method (Molecular, Chromosomal, Biochemical Tests), End User (Hospitals and Clinics) - Global Forecast to 2023
Erich Feldmeier

Tung, Barreiro, Johnson, Gilad Social stress affects immune system gene expression in m... - 0 views

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    "Previous research on rhesus macaques discovered that social rank influenced components of the stress response, brain, and immune system. With gene chip technology for measuring the expression of over 6,000 different genes, Tung, Gilad and colleagues at Yerkes, Emory University, and Johns Hopkins looked for the first time in primates at the effects of social rank on genetic function. Comparing 49 different female monkeys of different rank revealed significant changes in the expression of 987 genes, including 112 genes associated with immune system function. The result fits with data in monkeys where low rank and chronic stress lead to compromised immune function, and, more loosely, with human studies linking low socioeconomic status and high social stress to elevated disease risk."
Charles Daney

Mystery of Bird Maleness Partly Solved - 0 views

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    In a recent study, researchers show that a gene called DMRT1 found only on the Z chromosome partly explains bird "maleness". When a ZZ embryo gets less DMRT1, the embryos start to take on some female traits. These studies show us that bird gender can be partly explained by genetics. Not having enough of a single gene can keep a bird from becoming a bona fide male bird. But this doesn't rule out the possibility of a female gene being on the W chromosome. Scientists just haven't yet found one.
Erich Feldmeier

Gut Microbes May Foster Heart Disease | Wired Science | Wired.com - 0 views

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    ""We probably have underestimated the role our microbial flora play in modulating disease risk," says Daniel Rader, a heart disease specialist at the University of Pennsylvania School of Medicine. Rader, who was not involved in the study, says that gut bacteria may not be as big a factor in causing heart disease as diabetes or smoking, but could be important in tipping some people toward sickness. Researchers led by Stanley Hazen, a cardiologist at the Cleveland Clinic, didn't start out to study gut bacteria. In fact, says Hazen, he had "no clue - zero," that intestinal microbes were involved in heart disease. "I'd never even considered it or thought of the concept." Hazen and his colleagues compared blood plasma from healthy people to plasma from people who had had heart attacks, strokes or died to see if substances in the blood could predict who is in danger from heart disease. The researchers found 18 small molecules associated with fat buildup in the arteries. One of the best predictors turned out to be a byproduct made when gut bacteria break down a fat called choline (also known as lecithin). The more of this byproduct, called trimethylamine N-oxide or TMAO, a person or mouse has in the blood, the higher the risk of getting heart disease, the researchers found. Gut bacteria are actually middlemen in TMAO production. The microbes convert lecithin to a gas that smells like rotten fish. Then an enzyme in the liver changes the foul-smelling gas to TMAO."
Skeptical Debunker

What causes autism? Exploring the environmental contribution : Current Opinion in Pedia... - 0 views

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    Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.
Skeptical Debunker

If bonobo Kanzi can point as humans do, what other similarities can rearing reveal? - 0 views

  • The difference between pointing by the Great Ape Trust bonobos - the only ones in the world with receptive competence for spoken English - and other captive apes that make hand gestures is explained by the culture in which they were reared, according to the paper's authors: Janni Pedersen, an Iowa State University Ph.D. candidate conducting research for her dissertation at Great Ape Trust; Pär Segerdahl, a scientist from Sweden who has published several philosophical inquires into language; and William M. Fields, an ethnographer investigating language, culture and tools in non-human primates. Fields also is Great Ape Trust's director of scientific research. Because Kanzi, Panbanisha and Nyota were raised in a culture where pointing has a purpose - The Trust's hallmark Pan/Homo environment, where infant bonobos are reared with both bonobo (Pan paniscus) and human (Homo sapiens) influences - their pointing is as scientifically meaningful as their understanding of spoken English, Fields said. The pointing study supports and builds on previous research on the effect of rearing culture on cognitive capabilities, including the 40-year research corpus of Dr. Duane Rumbaugh, Dr. Sue Savage-Rumbaugh and Fields, which is the foundation of the scientific inquiry at Great Ape Trust. Those studies included the breakthrough finding that Kanzi and other bonobos with receptive competence for spoken English acquired language as human children do - by being exposed to it since infancy. The bonobos adopted finger-pointing behavior for the same reasons, because they were reared in a culture where pointing has meaning.
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    You may have more in common with Kanzi, Panbanisha and Nyota, three language-competent bonobos living at Great Ape Trust, than you thought. And those similarities, right at your fingertip, might one day tell scientists more about the effect of culture on neurological disorders that limit human expression. Among humans, pointing is a universal language, an alternative to spoken words to convey a message. Before they speak, infants point, a gesture scientists agree is closely associated with word learning. But when an ape points, scientists break rank on the question of whether pointing is a uniquely human behavior. Some of the world's leading voices in modern primatology have argued that although apes may gesture in a way that resembles human pointing, the genetic and cognitive differences between apes and humans are so great that the apes' signals have no specific intent. Not so, say Great Ape Trust scientists, who argued in a recently published scientific paper, "Why Apes Point: Pointing Gestures in Spontaneous Conversation of Language-Competent Pan/Homo Bonobos," that not only do Kanzi, Panbanisha and Nyota point with their index fingers in conversation as a human being might, these bonobos do so with specific intent and objectives in mind.
Janos Haits

Home | 1000 Genomes - 0 views

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    A Deep Catalog of Human Genetic Variation
Erich Feldmeier

Fred H. Gage and Alysson R. Muotri Jumping Genes in the Brain Ensure That Even Identica... - 0 views

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    "So-called jumping genes, segments of DNA that can copy and paste them­selves into new places in the genome, can alter the activity of full-length genes. Occasionally they will turn on neighboring genes in these locations. That activity occurs more in the brain than other areas, resulting in different traits and behaviors, even in closely related individuals. These mobile genetic elements may also turn out to play a role in people's disposition to psychiatric disorders"
Erich Feldmeier

Evidence of a genetic 'fountain of youth' discovered | ExtremeTech - 0 views

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    Calico , ETH Zurich "One in particular, the bcat-1 gene, seemed to have disproportionate effect on aging. "When we blocked the effect of this gene, it significantly extended the mean lifespan of the nematode by up to 25 percent," explains Professor Michael Ristow, coordinating author of the recently published study and Professor of Energy Metabolism at ETH Zurich."
anonymous

Mahendra Trivedi Science Research - 0 views

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    Unique science of Mahendra Trivedi. He has given extremely, amazing results in agriculture, materials science, plants genetics and biotechnology.
Ivan Pavlov

New findings challenge assumptions about origins of life - 0 views

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    Our genetic code is translated by two super-families of modern-day enzymes. Carter's research team created and superimposed digital three-dimensional versions of the two super-families to see how their structures aligned. Carter found that all the enzymes have virtually identical cores that can be extracted to produce "molecular fossils" he calls Urzymes-Ur meaning earliest or original. The other parts, he said, are variations that were introduced later, as evolution unfolded. These two Urzymes are as close as scientists have gotten to the actual ancient enzymes that would have populated the Earth billions of years ago.
thinkahol *

Jumping genes provide extensive 'raw material' for evolution, study finds - 0 views

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    ScienceDaily (June 2, 2010) - Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.
Charles Daney

The Great Beyond: Alzheimer's genes identified - 0 views

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    Three new genes associated with Alzheimer's have been discovered, to the delight of researchers in the field. In two papers published in Nature Genetics, two teams describe how they compared the genomes of sufferers to healthy controls to identify potential gene variations leading to the disease.
thinkahol *

Interview with Matthieu Ricard | Taking Charge of Your Health - 0 views

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    "More than 35 years ago, Matthieu Ricard left a promising career in cellular genetics to study Buddhism in the Himalayas. After earning a doctorate in biology from the prestigious Pasteur Institute in France, Ricard left Paris and moved to Darjeeling, India to study with a great Tibetan master. Today, Ricard draws upon his recent writings, research into brain plasticity and cognitive neuropsychology, and his work with neuroscientists and Buddhist practitioners at the Mind and Life Institute (co-founded by the Dalai Lama), while examining the interconnecting relationship between meditation, brain circuitry, and emotional balance."
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