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It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their "immortality". The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.

Vera Gorbunova and Andrei Seluanov of the University of Rochester have found that human cells undergoing oxidative stress caused by environmental chemicals or routine cellular processes produce a protein (SIRT6) that stimulates cells to repair DNA double-strand breaks, thought to be associated with premature aging and cancer. The team first measured levels of SIRT6 in stressed cells, then treated a second group of stressed cells with a drug that deactivates the protein. DNA repair in the second group stopped, confirming SIRT6′s role.  The team also found that SIRT6 acts in concert with another protein, called PARP1, to make the repairs. Furthermore, the team found that increased levels of SIRT6 lead to faster DNA repair. They suspect that the protein acts as a "master regulator," coordinating stress and DNA repair activities. Ref.: Zhiyong Mao, Christopher Hine, Xiao Tian, Michael Van Meter, Matthew Au, Amita Vaidya, Andrei Seluanov, and Vera Gorbunova. SIRT6 Promotes DNA Repair Under Stress by Activating PARP1. Science 17 June 2011: 1443-1446. [DOI:10.1126/science.1202723]

If your Windows 8 freezes on Startup, you can try the number of solutions being disucssed in this video

"In 2009, the scientific literature caught up with what top climate scientists have been saying privately for a few years now: * Many of the predicted impacts of human-caused climate change are occurring much faster than anybody expected - particularly ice melt, everywhere you look on the planet. * If we stay anywhere near our current emissions path, we are facing incalculable catastrophes by century's end, including rapid sea level rise, massive wildfires, widespread Dust-Bowlification, large oceanic dead zones, and 9°F warming - much of which could be all but irreversible for centuries. And that's not the worst-case scenario! * The consequences for human health and well being would be extreme. That's no surprise to anybody who has talked to leading climate scientists in recent years, read my book Hell and High Water (or a number of other books), or followed this blog. Still, it is a scientific reality that I don't think more than 2 people in 100 fully grasp, so I'm going to review here the past year in climate science. I'll focus primarily on the peer-reviewed literature, but also look at some major summary reports."

Dr. Mandelbrot, a maverick mathematician, developed an innovative theory to study uneven shapes and applied it to physics, biology and many other fields.

About the High Frequency Active Auroral Research Program.