Shot of Young Stem Cells Makes Rapidly Aging Mice Live Much Longer and Healthier - Gate... - 1 views
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animals that got the stem/progenitor cells improved their health and lived two to three times longer than expected,
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"Our experiments showed that mice that have progeria, a disorder of premature aging, were healthier and lived longer after an injection of stem cells from young, healthy animals," Dr. Niedernhofer said. "That tells us that stem cell dysfunction is a cause of the changes we see with aging."
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we injected stem/progenitor cells from young, healthy mice into the abdomens of 17-day-old progeria mice,
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"Typically the progeria mice die at around 21 to 28 days of age, but the treated animals lived far longer -- some even lived beyond 66 days. They also were in better general health."
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As the progeria mice age, they lose muscle mass in their hind limbs, hunch over, tremble, and move slowly and awkwardly. Affected mice that got a shot of stem cells just before showing the first signs of aging were more like normal mice, and they grew almost as large.