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Download the Mydatahelps app -- "When your heart beats faster than usual, it can mean that you're coming down with a cold, flu, coronavirus, or other viral infection. That's the conclusion of recent medical research. So wearable devices that measure your resting heart rate-made by Apple, Fitbit, Garmin, and others-might help scientists spot viral outbreaks, and also give you more insight into your own health. At Scripps Research, we've designed DETECT (Digital Engagement & Tracking for Early Control & Treatment), a study that will monitor your heart rate and allow you to record symptoms like fever or coughing."

"ABSTRACT Background: Heart rate variability (HRV), or variation in beat-to-beat intervals of the heart, is a quantitative measure of autonomic regulation of the cardiovascular system. Low HRV derived from electrocardiogram (ECG) recordings is reported to be related to physical frailty in older adults. Recent advances in wearable technology offer opportunities to more easily integrate monitoring of HRV into regular clinical geriatric health assessments. However, signals obtained from ECG versus wearable photoplethysmography (PPG) devices are different, and a critical first step preceding their widespread use is to determine whether HRV metrics derived from PPG devices also relate to older adults' physical function."

Recommended by Kabir: "Abstract Importance  Optimism and pessimism can be easily measured and are potentially modifiable mindsets that may be associated with cardiovascular risk and all-cause mortality. Objective  To conduct a meta-analysis and systematic review of the association between optimism and risk for future cardiovascular events and all-cause mortality. Data Sources and Study Selection  PubMed, Scopus, and PsycINFO electronic databases were systematically searched from inception through July 2, 2019, to identify all cohort studies investigating the association between optimism and pessimism and cardiovascular events and/or all-cause mortality by using the following Medical Subject Heading terms: optimism, optimistic explanatory style, pessimism, outcomes, endpoint, mortality, death, cardiovascular events, stroke, coronary artery disease, coronary heart disease, ischemic heart disease, and cardiovascular disease."

"Dr. Michael Kurisu D.O." called this video "molecurlar biology 101" It is from the Youtube Channel: MedCram - Medical Lectures Explained CLEARLY

Forwarded to the Project Apollo listserve by "Dr. Michael Kurisu D.O." from Christina Mnatzaganian. This is from the UCSD Family Medicine Faculty Listserve. Hi Deepa, The statement below is from ACC/HFSA/AHA on March 17th. Essentially, there is no human data yet and data is evolving. See below, particularly the red area: *The following joint statement from the ACC, American Heart Association and Heart Failure Society of America was posted online on March 17 and addresses using renin angiotensin aldosterone system (RAAS) antagonists in COVID-19. "The continued highest standard of care for cardiovascular disease patients diagnosed with COVID-19 is top priority, but there are no experimental or clinical data demonstrating beneficial or adverse outcomes among COVID-19 patients using ACE-I or ARB medications," said Richard J. Kovacs, MD, FACC. "We urge urgent, additional research that can guide us to optimal care for the millions of people worldwide with cardiovascular disease and who may contract COVID-19. These recommendations will be adjusted as needed to correspond with the latest research." Patients with underlying cardiovascular diseases appear to have an increased risk for adverse outcomes with coronavirus disease 2019 (COVID-19). Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients also may have severe cardiovascular damage. Angiotensin converting enzyme 2 (ACE2) receptors have been shown to be the entry point into human cells for SARS-CoV-2, the virus that causes COVID-19. In a few experimental studies with animal models, both angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) have been shown to upregulate ACE2 expression in the heart. Though these have not been shown in human studies, or in the setting of COVID-19, such potential upregulation of ACE2 by ACE inhibitors or ARBs has resulted in a speculation of potential increased risk for COVID-19 infection in patients with

"The Center is actively conducting numerous integrative health projects, including those examining effects of meditation, tai chi, acupuncture, guided imagery, journaling, and Ayurveda in heart failure, myocardial infarction, hypertension, cancer, multiple sclerosis, and pain patients."

Oura ring's Moments feature measures HRV. This is how we measure wellbeing. Test and measurement of wellbeing opens the door for so many interesting self studies. This should be one of the experimental choices in our new online class.

"David Fajgenbaum, MD, MBA, MSc, is the co-founder and Executive Director of the Castleman Disease Collaborative Network (CDCN) and one of the youngest individuals to be appointed to the faculty at Penn Medicine, where he is an Assistant Professor of Medicine in Translational Medicine & Human Genetics, Founding Director of the Center for Study & Treatment of Castleman & inflammatory Lymphadenopathies (CSTL). An NIH-funded physician-scientist, he has dedicated his life to discovering new treatments and cures for deadly disorders like idiopathic multicentric Castleman disease (iMCD), which he was diagnosed with during medical school. As common as ALS and more deadly than lymphoma, iMCD involves the immune system attacking and shutting down the body's vital organs such as the liver, kidneys, bone marrow, and heart. After spending months hospitalized in critical condition, having his last rites read, and having four deadly relapses, he is now in his longest remission ever thanks to a treatment that he identified in the lab."

"In 2009, Ms. Leon went to the WomenHeart Science and Leadership Symposium at the Mayo Clinic, where she met Dr. Sharonne N. Hayes, a professor of cardiovascular medicine at Mayo. At that time, the largest study on SCAD included 43 patients. "I walked up to Dr. Hayes and told her we had 70 people, and we wanted research," Ms. Leon recalled. "She was like, 'Wow.'" "Everything I learned about SCAD in my medical training was wrong," Dr. Hayes said. By 2010, with the help of Dr. Hayes, and subsequently SCAD Research Inc., an organization founded by Bob Alico, who lost his wife to SCAD, Dr. Hayes devised an innovative way to do research, using online networks of far-flung patients and analyzing genetic and clinical data. "We never imagined there would be 1,000 female patients in our virtual registry," Dr. Hayes said."

Click to download the PDF. Oura's primary goal is to help UCSF engage and increase the number of users who have rings and are opting in to early detection efforts. Oura is offering rings at $250 for orders of 1000 rings supporting TemPredict. Immediate impact: Participants are presented every morning with daily personalized insights on heart rate, HRv, respiration, temperature, sleep staging, and activity to empower them to monitor their own health and change their behavior accordingly. This is especially important in medical personnel and high-risk patients. Future impact: UCSF will leverage Oura's backend data to build models that can aid in identifying symptom profiles, pinpointing at risk populations, predicting severity, and validating recovery, containment, and treatment efforts. The data gathered now may be our only chance to measure these changes so we can recognize them and deploy predictive algorithms to minimize the next wave of this outbreak, expected in Fall 2020. We ask all donors to go to OuraRing.com and buy rings for medical personnel so they can join this effort.

Kabir speaks from the heart. Big Love.

Everyone ages at different rates. Our "true age" (also called "biological age") depends on how much inflammation we encounter in our lifestyle and environment, combining with our genetics. True age represents our capacity for resilience, in tolerating and recovering from these life stresses. By increasing this resilience, we could even get younger in true age! It requires frequent tracking of biomarkers like heart rate variability (HRV).

"One love. One heart." Bob Marley's everlasting message about the power of love and solidarity is more important than ever as families face the COVID-19 pandemic and millions call for equality.

"For the more than seven million people in California's Bay Area living through historic wildfires, it's been hard to breathe for the past month. For 29 days the region has been under a "Spare the Air" alert, which means inhaling outdoor air presents a health hazard. Air quality is even worse in Oregon and Washington, and by this morning smoke had stretched all the way to the East Coast and even to Europe. Wildfire smoke contains a variety of gases and particles from the materials that fuel the fire, including ozone, carbon monoxide, polycyclic aromatic compounds, nitrogen dioxide, and particulate matter-pollutants linked to respiratory and cardiovascular illnesses, according to a study in the Journal of the American Heart Association."

Recommended by DeAunne Denmark MD PhD: Our Mission To put compassion at the heart of healthcare through programs, education and advocacy. Our Vision: A world where all who seek and provide healthcare experience compassion.

"How do doctors, nurses, and other caring professionals keep their hearts soft when there are forces that make it hard to stay that way? With her radically compassionate approach to medicine, Dr. Victoria Sweet calls us to slow down in a world that loves quick fixes. In today's conversation, Kate and Victoria give us more language about what helps us all stay connected to the people we serve."

"Although each effort is being conducted separately, all of the studies center around a common principle that by establishing a baseline set of biometrics for every study participant - including temperature, heart rate, and activity and sleep levels - researchers can detect deviations that are suggestive of illness." "Forget precision medicine. This is precision health," said Michael Snyder, Stanford University School of Medicine genetics department chair and director of genomics and personalized medicine.

RARE‐X is committed to transforming rare disease by ensuring that patient communities, clinicians, researchers, and drug developers have access to the right data at the right time. At the heart of RARE‐X's approach is a belief that patients should own their data. In July 2021, RARE‐X launched itsfirst set of rare disease pilot programs on its data collection platform supported by data governance and consent that will ensure participants who spend the time to enter their data are able to share it with those stakeholders they choose.

About this podcast Sometimes it seems like you need Ninja skills to defeat Lyme disease. Join acupuncturist Mackay Rippey and his producer, Aurora, as they bring you interviews with interesting and informative people who are using their unique skills and knowledge to deal with Lyme and other tick born diseases. My name is Mackay Rippey, I'm an acupuncturist in Clinton, NY (http://www.mackayrippey.com)and the host of Lyme Ninja Radio. I'll never forget the Sunday morning I dragged my sorry-feeling-self to the bathroom and found a perfectly formed bullseye on my left arm. I was lucky, able to return to my acupuncture practice after only few days. It's possible to beat the bacteria that are making you sick. I have and so have many others, but you have to be smarter than Lyme. That's why I created Lyme Ninja Radio. Join us as we talk to some of the most interesting people in the Lyme community.

"Flattening the curve is not an option for the United States, for the UK or Germany. Don't tell your friends to flatten the curve. Let's start containment and stop the curve." Strong article with data visualizations from a Phd working out of MIT/Harvard.

DeAunne Denmark, MD, PhD - OUR CORE PREMISE: To improve health, we must close the gap between what we know and what we do. "INGH has a new facility and venture that is the best I've seen anywhere to get a whole slew of high-resolution data collected in one shot. And supposedly, it is "not that expensive"...