Bowhead whales (Balaena mysticetus), denizens of Arctic seas, are known to live more than 200 years, yet they show few signs of the age-related ailments that plague other animals, including humans. Even the bowhead's closest cetacean relative, the much smaller minke whale, lives only 50 years. That suggests the larger whales (which have more than 1000 times as many cells as humans) have evolved some special natural mechanisms that protect them against cancer and aging.
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That's why a paper published Thursday in the journal Genetics in Medicine is so remarkable.
The paper identifies NGLY1 deficiency as an inherited genetic disorder, caused by mutations in the NGLY1 gene. The researchers have confirmed eight patients with these mutations who share several symptoms, including developmental delays, abnormal tear production and liver disease.
Most siblings with a diagnosis of autism do not share the same genetic risk factors for the disorder and are as distinct in their behaviors as any brothers and sisters, scientists reported on Monday in a study that came as a surprise to many doctors, if not to parents.
New research shows our DNA is absolutely loaded with... NOTHING. 98 percent of our DNA plays no role in our development. But as Trace learns, the findings may not be so black and white.