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Hands on lab activities

The club, which has about 20 members, is researching the culture and regrowth of methanotrophic bacteria, using a wide variety of experiments and individual projects. The students meet every Thursday with their advisor, Michael Ralph, and they also work during their own time.

Phys.org) -Scientists at the University of Virginia School of Medicine have overcome one of the greatest challenges in biology and taken a major step toward being able to grow whole organs and tissues from stem cells. By manipulating the appropriate signaling, the U.Va. researchers have turned embryonic stem cells into a fish embryo, essentially controlling embryonic development.

All introductory biology textbooks, and many sophomore-level genetics textbooks as well, describe several classic experiments in molecular biology. This interrupted case study takes students through two of these classic experiments, namely, those by Griffith and Avery, McCarty and MacLeod that showed DNA to be the genetic material in Streptococcus pneumoniae, and the experiment by Meselson and Stahl that demonstrated DNA replication to be semiconservative. Engaging students with the experiments in a more exploratory manner can reinforce the nature of scientific discovery and the logic behind these findings. The case, which has been formatted as two separate exercises that can be used independently, was developed for use in introductory biology classes for biology majors. The material is accessible enough to also be useful for non-majors college biology or high school AP biology students.

We create interactive lessons for high school and college educators to engage their students in discussions of ethics and personal genetics. The lessons are relevant to multiple subjects, including biology, health, social studies, law, physical education and psychology. All of our lesson plans contain background reading for teachers and students, a selection of classroom activities, discussion points, in some cases a slide presentation or video clip, and an evaluation. Each lesson can stand alone, or all the lessons can be taught as a unit.

"CRACKING THE CODE"/"Cloning Paper Plasmid" activities can (1) serve as a review of the "genetic code" and the role it plays in our life; and, (2) to help students see how genes may be manipulated for genetic research, namely, gene cloning/genetic engineering. The laboratory time, the specialized equipment and expertise to carry out recombinant DNA experiments may be lacking in the high school. Activity 2 will help students conceptualize the mechanics involved in cutting and ligating DNAs into a plasmid vector with "sticky ends" of complementary DNA base pairs.

The Ethics Primer provides engaging, interactive, and classroom-friendly lesson ideas for integrating ethical issues into a science classroom. It also provides basic background on ethics as a discipline, with straightforward descriptions of major ethical theories. Several decision-making frameworks are included to help students apply reasoned analysis to ethical issues. Although the Primer is designed for secondary school science classrooms, it has been used by teachers in a variety of classes and grade levels. It is particularly suited to social studies and integrated/interdisciplinary classrooms. It has also been used with adults. The Primer is not designed to be used cover to cover. Teachers should review materials and select lessons that fit their needs. The Primer is also intended to be used as a general resource, with a wide variety of topics.

When Jordan is diagnosed with brain cancer (glioblastoma multiform), his college plans are unexpectedly put on hold. This scenario is presented in order to teach students about gene regulation, as the efficacy of the drug Jordan receives for post-surgical treatment is dependent upon the activity level of a gene encoding a protein involved in DNA repair. This "flipped" case study requires students to prepare in advance outside of class by watching several short videos that have been selected to teach the basics of how cancer forms as well as the role of epigenetics in gene silencing. Inside of class, the case is delivered using progressive disclosure format in which students gradually receive additional information to answer a series of directed questions. To determine a treatment plan for Jordan, students analyze data from a research study involving patients treated for his specific type of cancer. The case is designed for advanced high school biology classes as well as lower-level undergraduate general biology courses for non-majors and majors.

Millions of people suffer from asthma, a frightening disease that makes you feel like you're drowning. Using both mouse and human cells - and a humanized mouse to show how human type 2 innate lymphoid cells (ILC2) work in the body, researchers at Janssen Research and Development, Dana-Farber Cancer Institute and Harvard Medical School are figuring out ILC2's role in asthma. Their findings have important implications in the quest for effective asthma therapies!

The early stages of embryonic development shape our cells and tissues for life. It is during this time that our newly formed cells are transformed into heart, skin, nerve or other cell types. Scientists are finding that this process is largely controlled not by the genome, but by the epigenome, chemical markers on DNA that tell cells when to turn genes on and off. Now, studying zebrafish embryos, researchers at Washington University School of Medicine in St. Louis have shown that the epigenome plays a significant part in guiding development in the first 24 hours after fertilization.

Australian outfit Bridge 8, who have the admirable mission of devising "creative strategies for science and society," and animator James Hutson have created six fantastic two-minute animations on various aspects of critical thinking, aimed at school ages 8 to 10, or kids between the ages of 13 and 15, but also designed to resonate with grown-ups. Inspired by the animation style of the 1950s, most recognizably Saul Bass, the films are designed to promote a set of educational resources on critical thinking by TechNYou, an emerging technologies public information project funded by the Australian government.

Emerging diseases and potential pandemics make the news nearly every year. Students (and everyone else) may wonder where new infectious diseases come from, how scientists assess the risk of a pandemic, and how we might go about preventing one. This case study uses a PowerPoint presentation to explore these questions by focusing on HIV, a pandemic that began as an emerging disease. The storyline progresses backwards through time as scientists attempt to unravel the origins of a new, mysterious plague. Much of the case relies on audio excerpts from an episode produced by Radiolab, an acclaimed radio show that explores a variety of topics in science and culture (www. radiolab.org). Students use graphics, animations, and sound clips presented in the PowerPoint slides to discuss several sets of questions. The case is suitable for a wide range of high school and college introductory biology courses, as well as undergraduate microbiology, ethics, and public health courses.

This case study centers on an active teaching game that simulates a cholera outbreak among five villages along a river, similar to the Haitian outbreak of 2010. By enacting the behaviors of fictional villagers, students learn how trade, travel, sanitation practices and geographic location contribute to the spread of diarrheal disease. Documenting various contamination events of village water supplies allows students to trace the progression of the disease and illustrates how adequate sanitation facilities provide protection against the bacteria Vibrio cholera. Originally designed for an undergraduate upper-division biology course focusing on the epidemiology of diseases, the simulation is also appropriate for microbiology and public health courses, as well as lower division undergraduate biology courses and high school. Biology or epidemiology components of the case study can be highlighted depending on the emphasis of the course being taught. The game can be completed within a 45- to 60-minute class period. Playing cards are available from the Supplemental Materials tab; detailed instructions are found in the teaching notes.

The complex systems of high school dating and chemical reactions may have more in common than you think. Explore five rules for speeding up chemical reactions in the lab that might just land you a date to a dance!

STEM PBL cases for purchase from Wake Forest School of Medicine.  HS topics tagged.

4:00 video 93% of Americans agree that sex education should be taught in schools, but what's the best approach to get teens to practice safe sex? Read More: Sex Education Delays Teens' Sexual Activity http://www.huffingtonpost.com/2012/03... "Teens who receive formal sex education wait longer to have sex, a new study finds - and when they do get around to doing the deed, they're more likely than teens who haven't had sex ed to use contraception." Sex Education in the U.S. is Screwing Our Kids http://www.salon.com/2014/12/01/why_s... "Government-funded abstinence programs and a lack of instructor training are failing the country's teens." Teaching Good Sex http://www.nytimes.com/2011/11/20/mag... "Across the country, the approach ranges from abstinence until marriage is the only acceptable choice, contraceptives don't work and premarital sex is physically and emotionally harmful, to abstinence is usually best, but if you must have sex, here are some ways to protect yourself from pregnancy and disease."

Scientists are now one step closer to understanding how genetic mutations contribute to autism. In a study released Thursday in the journal Cell, experts from UNC School of Medicine discovered how one specific autism-linked gene mutation actually works

myBrainshark is a superb tool that allows students to add a voiceover to PowerPoint presentations, Word documents, videos and photo albums -- or to simply produce podcasts. It then blends the visual and audio components together into a video presentation. In the classroom, your students can present completed projects using myBrainshark, rather than face-to-face, or they can use it for mock presentations allowing the teacher to give feedback before the real presentation. The former can help bolster the confidence and communication skills of introverted and/or passive learners. Teachers can also turn their PowerPoint presentations into narrated video presentations (e.g. explanation of concepts) that students can watch outside of school hours. The most immediate limitation of this tool is that presentations cannot be downloaded in the free version. If you are looking for a tool that also allows for video narratives along with PowerPoint presentations (instead of basic audio), I would suggest Present.me.

National geographic site with high school lessons on: - captive breeding, species survival, and case studies. -Video clips are also available

This case study presents the story of "Nick," a student who has been assigned the task of writing a research paper describing the fundamentals of chemical bonds and how they relate to human life. When Nick experiences difficulty remembering information about the different types of chemical bonds, he turns to his tutor, Josh, for help. Josh explains orbitals and valence electrons to Nick, and then they together review nonpolar and polar covalent bonds, ionic bonds, and hydrogen bonds. A final practical application exercise requires that students write about how different types of chemical bonds may relate to the development of Alzheimer's disease and to the mechanism of action of potential drug treatments.  The case is presented with PowerPoint slides and is designed to be used with a personal response system ("clickers"), but students can instead record their answers on paper or share them verbally.  The content is appropriate for use in high school and undergraduate introductory chemistry and biology courses.