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Session description: The session will provide an introduction to the ethics of research involving human participants. It will ad-dress the history of research ethics, present a contemporary eth-ical framework, and discuss its application to differing kinds of research studies. The ethical framework consists of four principles: respect for persons, beneficence, justice, and respect for communities. Each principle provides the foundation for ethical rules, including requirements for informed consent and confidentiality of health information. Taken together these ethical principles and rules provide a comprehensive framework for the analysis of ethical challenges in health research.

Although Hardy-Weinberg equilibrium is a fundamental part of introductory biology classes, students often have difficulty understanding its implications. This interrupted case study places students in the role of small teams who are conducting preliminary research into the impact of roads on the population structure of timber rattlesnakes in order to apply for a grant for further research. Research groups consisting of 3-4 students work through a series of questions allowing them to use HWE principles to discover for themselves how deviations from HWE can have implications for conservation biology. Periodic interruptions with help sheets (see Supplemental Materials) allow teachers to maintain an active role in the students' progress, while also demonstrating the collaborative nature of scientific research. Ultimately students formulate formal emails summarizing and interpreting their findings in order to "apply" for the grant. The case is designed for undergraduate students in introductory biology or in lower-level population genetics/conservation courses where connecting basic genetic principles to ecology and sustainability is key.

Students use DNA profiling to determine who robbed a bank. After they learn how the FBI's Combined DNA Index System (CODIS) is used to match crime scene DNA with tissue sample DNA, students use CODIS principles and sample DNA fragments to determine which of three suspects matches evidence obtain at a crime location. They communicate their results as if they were biomedical engineers reporting to a police crime scene investigation.

In this laboratory you will use some basic tools of molecular biology to gain an understanding of some of the principles and techniques of genetic engineering. In the first part of the lab, you will use antibiotic-resistance plasmids to transform Escherichia coli. In the second part, you will use gel electrophoresis to separate fragments of DNA for further analysis.

This interrupted case study was inspired by and uses data from one of the largest commercial restaurant associated outbreaks of norovirus reported in the literature. It applies basic principles of epidemiology and outbreak investigation to a shellfish-linked norovirus outbreak at a Michelin star restaurant in the UK in 2009. The details of the case are taken directly from the report that was produced by the health protection agency and publications that followed. Students take on the role of an infection control team (ICT) that is responsible for identifying the extent and source of the outbreak. They are taken through different stages of the outbreak investigation and at each stage asked what their team would do in response to given pieces of information. Specifically, students uncover the scope and source of the outbreak using descriptive and basic analytical epidemiology methods. The case is suitable for first or second year introductory courses in microbiology, epidemiology, or other infectious disease related topics.

Promotes accurate understanding and comprehensive teaching of evolutionary theory for a wide audience Explores the practical applications of evolutionary principles in daily life and the impact of evolutionary theory on culture and society throughout history Offers teaching tools such as unit and lesson plans and classroom activities, as well as additional online content such as podcasts and powerpoint presentations

An elderly woman living independently with some help from her family is brought to the local emergency room because she is confused and vomiting. While her son suspects a stroke, a quick battery of laboratory tests indicates that her current problems are the result of impaired kidney function, an old-fashioned home remedy for ulcers, and her prescribed blood pressure medication. The combination of patient- and drug-related factors produces an acid-base disorder responsible for her confusion. This disorder further disrupts her kidney function. The case illustrates secretion and reabsorption processes in the kidney tubule which regulate plasma and urinary electrolytes (including calcium) and pH. The role of bicarbonate in maintaining systemic pH is emphasized. Interactions among the renal, respiratory and nervous systems in the regulation of systemic pH are also illustrated. Further, basic principles of pharmacotherapy and issues related to the appropriate use of medications are introduced. The case was developed for use in a physiology or human anatomy and physiology course, but it might be used in undergraduate nursing courses as well (e.g., pharmacology, pathophysiology).

 Do the principles of the Belmont Report address all the ethical issues that arise in evolving research scenarios? (November, 2013) Watch the full video - http://www.peopleandperspectives.org/... People & Perspectives (P&P) is a digital oral history library supported by Public Responsibility in Medicine & Research (PRIM&R). Visit http://www.peopleandperspectives.org to learn more. P&P features stories of those working in research ethics, many of whom were involved in the early years of the field. Those featured include IRB and IACUC professionals, research staff, committee members, institutional officials, researchers, subjects, advocates, regulators, industry representatives, ethicists, and others who consider themselves part of the human subjects and animal care and use enterprise.

This case study is used to teach undergraduate students about hydraulic fracturing (hydrofracking), a controversial method for extracting methane from shale. The controversy arises from claims that chemicals used in the fracking process and the methane itself find their way into drinking water and are also sometimes found at dangerous levels in the air. The case study begins in a college chemistry class where a student inquires about a news item he saw about residents setting their tap water on fire. The instructor uses this as an opportunity for the students to research hydrofracking and natural gas, and she then integrate these topics into their present study of isotopes. The class first examines what isotopes are by using a guided inquiry based activity. The students then learn how mass spectrometry, which uses the principles just learned about isotopes, is employed to determine the source of methane in contaminated wells. This case study is designed for freshman chemistry students and students in environmental studies.

This hands-on activity, used in conjunction with the film The Making of the Fittest: Natural Selection in Humans, teaches students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits. It uses simple simulations to illustrate these complex concepts and includes exercises such as calculating allele and genotype frequencies, graphing and interpretation of data, and designing experiments to reinforce key concepts in population genetics.

2:10 video Science expert Emerald Robinson explains what the study of biology is and what we learn from it.  Outlines 5 unifying principles.

 Students must consider the role of rumen bacteria and how genetic modification may alter the potential of these bacteria. The case engages students in learning basic principles of bacterial genetics and biotechnology as they consider how microbes and microbial processes impact the environment. The case could also be used in an introductory genetics or biotechnology course.

Life sciences focus on all things living, exploring the patterns, processes and relationships of organisms. The goal of life sciences is to demonstrate how unifying principles can help us to make sense of the natural world and solve problems in the world we live in. High school life sciences extend student knowledge of topics such as organisms, ecosystems, heredity and evolution, integrating a long history of scientific research from multiple fields. In high school, students will build on their conceptual understanding of life sciences by investigating and witnessing the relationships among structure and function, matter and energy, ecosystems and natural selection. Students should be able to effectively communicate facts and findings, as supported in the science literacy skills covered in the Common Core State Standards.

Taxonomy groups species by common traits. Modern taxonomy emphasizes evolutionary relatedness. Explore some principles of taxonomy by sorting twenty shells by their morphological characteristics. Whenever a pictorial index of shells appears, you can click on an image of a shell to open it in a separate window. There you can click and drag your mouse over the shell to rotate it for a more detailed examination. Additionally, you can use the small buttons in the lower right corner of the window to rotate the shell.

This interactive case discussion was created to emphasize the clinical relevance of population genetics, but is also a suitable resource for teaching the basic principles of population genetics while relating them to human genetic variation. Our understanding of human genetic variation has deepened over the past decade due to fine-scale genome mapping. Applying this knowledge to the evaluation of ancestry-based genetic testing strategies, such as direct-to-consumer genetic testing, is an important component of the practice of culturally-competent medicine and a relevant way to teach the foundations of population genetics, including Hardy-Weinberg equilibrium.

CASES Online is a collection of investigative lessons, or "cases," for K-12 and undergraduate science education. Using principles of Problem-Based Learning and Investigative Case-Based Learning (and related student-centered pedagogies), our cases are designed to engage students in exploring the science behind real-world problems. Our cases address a variety of learning objectives across the sciences and mathematics. Although our K-12 cases were designed for use in Georgia and meet our state education standards, we have also included the relevant National Science Education Standards. CASES Online is designed to be used by K-12 and undergraduate science educators. By searching our collection, educators can find cases appropriate to their grade levels, subjects, and topics of interest. In order to download case materials for use in the classroom, educators must first register. While there is no charge to register, download, or use these cases -- we request that all users follow the guidelines outlined under our Terms of Use. Educators are also encouraged to submit cases of their own to our collection. To learn how best to use CASES Online, explore the User Guide; otherwise, begin to transform your classroom by searching for cases.

The SAT Biology E/M Subject Test is a multiple-choice test with 80 questions. You'll answer 60 multiple-choice questions on core principles in biology; then, depending on the additional subject matter you selected, you'll answer an additional 20 multiple-choice questions on Biology-E or Biology-M subject matter. You'll have one hour to answer all 80 questions.

The Virtual Biology Lab Project is designed to provide interactive activities that demonstrate ecological principles. We provide agent-based models that simulate classic ecological experiments or concepts across a wide range of ecological topics. Students manipulate experimental parameters and observe the results. These results are provided numerically and graphically and are reinforced with a visualization of the model's "world". The content is suitable for advanced high-school and college students.

This flipped case was designed to introduce students in a general introductory biology course to basic protein structure. The two videos and interrupted case use keratins in hair as model proteins. From the videos students learn how amino acids regulate protein structure, and how small changes in amino acid sequence have large impacts on overall protein organization and function. The case story focuses on a puppy whose hair changes from straight to curly when it sheds its coat. The protagonist tests the adult versus puppy hair, and discovers that the amino acid composition is different in the curly versus straight hair samples. Students apply basic principles of protein structure to hypothesize why the dog's coat switched from straight to curly. The case intentionally stops short of providing a complete answer to the mystery, so students think through the molecular processes logically rather than having a final "correct" answer. An optional activity is provided that makes the case more appropriate for an introductory cell biology class.

The Hardy-Weinberg equation is a relatively simple mathematical equation that describes a very important principle of population genetics: the amount of genetic variation in a population will remain the same from generation to generation unless there are factors driving the frequencies of certain alleles (genetic variants) to change.