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Welcome to the HealthStats Indicator Report Categorized Index. This categorized index provides a selection menu in the form of an explorer type hierarchical folder tree and is organized by topic or subject area. These menu selections are used to navigate to the system's various indicator reports. Listed below are the most general categorized index menu sections. After selecting one of these general category sections, a page will be presented which will allow the folder's sub items to be shown and selected.

EPA is working with many other organizations to collect and communicate data about climate change. With help from these partners, EPA has compiled the third edition of this report, presenting 30 indicators to help readers understand observed long-term trends related to the causes and effects of climate change. In a manner accessible to all audiences, the report describes the significance of these trends and their possible consequences for people, the environment, and society.

This indicates that the mutation originated in just one person who became the ancestor of all subsequent people in the world with blue eyes, according to a study by Professor Hans Eiberg and colleagues at the University of Copenhagen.

Parkinson's is a result of the loss of cells in various parts of the brain, including one portion that produces the neurotransmitter dopamine. Dopamine is essential for being able to move in a coordinated way, so the loss of dopamine causes the tremors often associated with the condition. While the exact cause of Parkinson's is unknown, genetics and environment are contributing factors. Most cases occur in patients with no family history of Parkinson's disease, but there are 13 gene mutations that have been linked to either causing the disease or increasing one's risk of developing it. Certainly not everyone who carries these gene mutations develops Parkinson's, but identifying these genetic indicators is the beginning of developing more precise treatments.

A link has been made between sleep apnoea - which is often indicated by loud snoring - and worse cancer outcomes in recent studies.

Healthy plants reflect more near-infrared light than stressed plants, so bright red indicates dense, growing foliage. For this reason, biologists and ecologists occasionally use infrared cameras to photograph forests. 

An elderly woman living independently with some help from her family is brought to the local emergency room because she is confused and vomiting. While her son suspects a stroke, a quick battery of laboratory tests indicates that her current problems are the result of impaired kidney function, an old-fashioned home remedy for ulcers, and her prescribed blood pressure medication. The combination of patient- and drug-related factors produces an acid-base disorder responsible for her confusion. This disorder further disrupts her kidney function. The case illustrates secretion and reabsorption processes in the kidney tubule which regulate plasma and urinary electrolytes (including calcium) and pH. The role of bicarbonate in maintaining systemic pH is emphasized. Interactions among the renal, respiratory and nervous systems in the regulation of systemic pH are also illustrated. Further, basic principles of pharmacotherapy and issues related to the appropriate use of medications are introduced. The case was developed for use in a physiology or human anatomy and physiology course, but it might be used in undergraduate nursing courses as well (e.g., pharmacology, pathophysiology).

In a retrospective cohort study investigating the role of epigenetic control in the onset of allergic diseases, it was shown that mothers who suffered from allergic symptoms very early in pregnancy were more likely to have offspring with allergies. This was compared to mothers who did not suffer from allergies in early pregnancy, taking into account family history of allergies and total allergic response during pregnancy (10). These results indicate that gene-environment interactions during embryonic development may modify the epigenetic code in ways that may potentially lead to allergic disease.

The most recent human retroviral infections leading to germ line integration took place with a subgroup of human endogenous retroviruses called HERVK(HML-2). The human genome contains ~90 copies of these viral genomes, which might have infected human ancestors as recently as 200,000 years ago. HERVs do not produce infectious virus: not only is the viral genome silenced - no mRNAs are produced - but they are littered with lethal mutations that have accumulated over time. A recent study revealed that HERVK mRNAs are produced during normal human embryogenesis. Viral RNAs were detected beginning at the 8-cell stage, through epiblast cells in preimplantation embryos, until formation of embryonic stem cells (illustrated). At this point the production of HERVK mRNA ceases. Viral capsid protein was detected in blastocysts, and electron microscopy revealed the presence of virus-like particles similar to those found in reconstructed HERVK particles. These results indicate that retroviral proteins and particles are present during human development, up until implantation.

The possibilities of pseudo-peptide-DNA mimics like PNA (peptide nucleic acid) having a role for the prebiotic origin of life prior to an RNA world is discussed on the basis of literature data showing that this type of molecules might have formed on the primitive earth (or other places in the universe), as well as data indicating the possibilities of template-directed PNA chemical replication and ligation. In particular, the merits of an achiral prebiotic genetic material is discussed.

Existing mouse models of lethal Ebola virus infection do not reproduce hallmark symptoms of Ebola hemorrhagic fever, neither delayed blood coagulation and disseminated intravascular coagulation, nor death from shock, thus restricting pathogenesis studies to non-human primates. Here we show that mice from the Collaborative Cross exhibit distinct disease phenotypes following mouse-adapted Ebola virus infection. Phenotypes range from complete resistance to lethal disease to severe hemorrhagic fever characterized by prolonged coagulation times and 100% mortality. Inflammatory signaling was associated with vascular permeability and endothelial activation, and resistance to lethal infection arose by induction of lymphocyte differentiation and cellular adhesion, likely mediated by the susceptibility allele Tek. These data indicate that genetic background determines susceptibility to Ebola hemorrhagic fever.

Concept maps are tools for organizing and representing knowledge. They include concepts, usually enclosed in circles or boxes of some type, and relationships between concepts or propositions, (indicated by a connecting line and linking word) between two concepts. Linking words on the line specify the relationship between the two concepts. Joe Novak defines "concept" as a perceived regularity in events or objects, or records of events or objects, designated by a label. Think of the concept "Dog" in your mind, what do you see? You might see a prototype shape (head, four legs etc) and typical examples (terrier, collie, sheepdog) and even be able to explain it (give a definition) in words. The label for most concepts is a word, although sometimes we use symbols such as + or %. Propositions are statements about some object or event in the universe, either naturally occurring or constructed. Propositions contain two or more concepts connected with other words to form a meaningful statement. Sometimes these are called semantic units,or units of meaning. Figure 1 shows an example of a concept map that describes the structure of concept maps and illustrates the above characteristics.

In the closing sentence of "The Origin of Species," Charles Darwin marvels at the process of evolution, observing how "from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved." Few people would describe bedbugs as most beautiful or most wonderful. Yet this blood-feeding pest may represent an exceptional chance to observe the emergence of Darwin's "endless forms": New research indicates that some bedbugs are well on their way to becoming a new species.

This interrupted case study addresses several concepts related to climate change and its effect on the American pika. Often called an indicator species for climate change, the pika has a unique set of variables specific to its environment. Factors such as temperature, snowpack, and vegetation can affect the distribution and ultimately the chances of survival. The case was designed for use in a "flipped" classroom in which students prepare in advance outside of class by filling out a worksheet while watching a video. The video, created by the author of the case, provides students with baseline information that they apply in class to come up with key ideas and predictions, followed by analysis of actual data to test the hypotheses they develop. The case study incorporates group discussion, analysis of experimental design, and data evaluation as central activities and can be taught in a single 50 minute class session. The case was designed for use in a large introductory-level class, but is also appropriate for smaller classes.

Humans, like all animals, need sleep, along with food, water and oxygen, to survive. For humans sleep is a vital indicator of overall health and well-being. We spend up to one-third of our lives asleep, and the overall state of our "sleep health " remains an essential question throughout our lifespan. Most of us know that getting a good night's sleep is important, but too few of us actually make those eight or so hours between the sheets a priority. For many of us with sleep debt, we've forgotten what "being really, truly rested" feels like.

This case study follows two beginning undergraduate researchers on a quest for a summer research project related to food web ecology. While writing their research proposal, the students receive feedback indicating that they have neglected an entire group of organisms from their food web-parasites, which leads them to a scientific research paper discussing how these organisms have been overlooked by scientists studying food webs, the challenges involved with including parasites in food webs, and the contributions parasites ultimately make to food webs. An integrated activity in which students visualize the food web using images of organisms and answer questions about species interactions provides opportunities to examine key concepts such as omnivory, ontogenetic diet changes, trophic levels, complex life cycles, and taxonomic aggregation. This case study was originally written for an undergraduate general ecology course, but could easily be adapted to undergraduate general biology courses covering community ecology or specific courses in invertebrate zoology, parasitology, or disease ecology. The teaching notes also discuss how the included code for R statistical computing software can be used to extend the case study in a more quantitative direction if desired.

Flinn Scientific has launched a website with an extensive amount of resources specifically developed to help teachers, students and parents continue their science education journey - even if that learning is taking place outside the classroom or laboratory environment. Examples of some of the resources we have developed: Free video labs with related teacher and student guides to help students at home continue making progress on key science topics More than 40 free, easy and fun-to-do activities that use commonly available materials to encourage science investigation in the home Flinn's unique digital learning solutions to facilitate seamless science learning. These online solutions are the perfect way to efficiently scale curriculum in an at-home setting - also free of charge On call scientists: over the coming days, we will be releasing video based lab experiments conducted by our scientific staff and broadcast from our studio with live events. As part of each live event, we will have our full team of scientists available to answer questions from teachers and students participating online - also free of charge and highly interactive and engaging. Be sure to check out our online calendar indicating the live schedule

This case study uses an interactive activity to illustrate density dependence in ecology classes. We developed a "hunt" using paper butterflies with warning signals on the upper side of the wings and symbols that indicate if a butterfly is noxious underneath the wings. Butterflies are distributed in four different patches with varying densities of noxious and palatable butterflies, simulating Batesian or Müllerian mimicry. Students can catch as many butterflies they want for a period of time, but if they catch more than three noxious butterflies they are out of the game. After the activity, students calculate the survival rate of each type of butterfly in each patch and discuss the implications of density and warning signals according to their results. Students then answer questions and build graphs using the data from the activity and knowledge from the class and the discussion. With this case study, students will be able to understand negative and positive density dependence, as well as predation, learning, and convergent evolution, while recalling or being introduced to Batesian and Müllerian mimicry.

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Most siblings with a diagnosis of autism do not share the same genetic risk factors for the disorder and are as distinct in their behaviors as any brothers and sisters, scientists reported on Monday in a study that came as a surprise to many doctors, if not to parents.