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A new study from the Monell Center, the U.S. Department of Agriculture (USDA), and collaborating institutions reports a uniquely identifiable odor signature from mouse models of Alzheimer's disease. The odor signature appears in urine before significant development of Alzheimer-related brain pathology, suggesting that it may be possible to develop a non-invasive tool for early diagnosis of Alzheimer's disease.

By early 2014, Flint, Kendler and a team of collaborators had analysed DNA sequences from 5,303 Chinese women with depression, and another 5,337 controls. As Flint expected, 85% of the depressed women had a severe form of the disorder called melancholia, which robs people of the ability to feel joy. "You can be a doting grandparent and your favourite grandchildren can show up at your door," says Douglas Levinson, a psychiatrist at Stanford University in California, "and you can't feel anything." The analysis yielded two genetic sequences that seemed to be linked to depression: one in a stretch of DNA that codes for an enzyme whose function is not fully understood, and the other next to the gene SIRT1, which is important for energy-producing cell structures called mitochondria. The correlations were confirmed in another set of more than 3,000 depressed men and women and over 3,000 controls.

"Thus far, the lineages of wolves that likely gave rise to dogs have not yet been discovered and it's possible that these puppies could be on that lineage, which would be very exciting," said evolutionary biologist Greger Larson, of the University of Oxford, one of the scientists behind a collaborative project aimed at finding out when and where dogs became the first domesticated animals.

This case study provides an overview of the seminal experimental work that led to the discovery of DNA structure and the confirmation of the semi-conservative model of DNA replication. By guiding students through a chronological series of historic experiments and discussing some of the collaborations and controversies involved in the original research, students learn about the history and nature of science in addition to several important biological concepts. A number of recommended videos, including one created by the author, enable instructors to use the "flipped-classroom" mode of instruction according to which students read primary literature and watch videos on their own before group discussions and activities. The case study was developed for use in an introductory undergraduate biology course, and would also be appropriate for use in a high school biology course. Some prior knowledge or instruction may be required, depending on the level and learning objectives of the course.

This case study tells the story of a group of ten men, recently released from federal penitentiaries, who are housed in a residential reentry center for the remainder of their sentences. Their stay is intended to bridge the gap between incarceration and return to life in the community. Due to the length of time served, the men are poorly skilled in healthy behaviors and self-reliance in the areas of food and activity. Although a work of fiction, the narrative realistically portrays a variety of challenges that the men face including a chronic health issue, menu planning, tight budgets, hunger, boredom, lack of cooking skills, and life without a local supermarket. Innovation, trial and error, and collaboration result in a story of resilience and health behavior change in a sparsely populated area of Northern Michigan. The case was originally developed for a college-level nutrition course, but could also be used in social work, community health, and health education, nursing, and dietetics classes.

Now eight years old, USAID PREDICT is a collaborative effort to monitor, predict and prevent emerging diseases, many of them zoonotic, from becoming devastating global pandemics the likes of Ebola. It's led by Jonna Mazet, an epidemiologist at the University of California at Davis's One Health Institute and School of Veterinary Medicine, and also partners with the Wildlife Conservation Society, Metabiota, EcoHealth Alliance and the Smithsonian Institution's Global Health Program.

What do we care most about? We care about social collaboration, immersing students in investigations of science phenomena, developing artifacts that demonstrate rigorous learning, and then presenting those artifacts for community use.

The data comes from the open Tree of Life Project, a collaboration among biologists and other scientists around the world. It contains decades' worth of work in phylogeny, evolutionary history of and relationships among groups of organisms. The project is about a year away from a complete tree of all life, Rosindell said. He wanted a system in place that could visualize it as soon as it's ready. Right now, OneZoom only contains mammals, but that's still more than 5,000 species, all correlated with each other and color-coded according to their threat levels. Rosindell has big plans for the rest, and he even wants to build a searchable app for smartphones, showcasing the history and relationships between all life on Earth.

Variety of sample rubrics

Rubrics for a wide array of work products, West Virginia Dept of Education

Here is a list of additional resources for Inquire High School. These inquiry resources include great links to Web sites, articles, videos, and much more that supports inquiry

This web site provides tools and resources that support ambitious science instruction at the middle school and high school levels. Ambitious teaching deliberately aims to get students of all racial, ethnic, and class backgrounds to understand science ideas, participate in the discourses of the discipline, and solve authentic problems. We describe 4 core instructional strategies that support this kind of teaching. These "high-leverage" practices make up the Science Learning Framework (below), and have been selected based on extensive research of how young people learn science, on authentic forms of science activity, and how teachers learn to appropriate new practices.