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This Funding Opportunity Announcement (FOA) encourages applications for Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54s). The mission of the CounterACT program is to foster and support research and development of new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare agents, toxic industrial chemicals, pharmaceutical-based agents, and pesticides. The scope of the research includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy consistent with the product's intended use in humans. For applicants submitting U54 renewal applications, research under this FOA should culminate in an optimized lead compound ready for advanced development. The Centers will contain at least three research projects supported by an administrative core, up to three optional scientific cores, and a research education core. Each research project must include milestones that create discrete go or no-go decision points in a progressive translational study plan.

The proliferation of mobile and Internet-of-Things (IoT) devices, and their pervasiveness across nearly every sphere of our society, continues to raise questions about the architectures that organize tomorrow’s compute infrastructure. At the heart of this trend is the data that will be generated as myriad devices and application services operate simultaneously to digitize a complex domain like a smart building or smart industrial facility. A key shift is from edge devices consuming data produced in the cloud to edge devices being a voluminous producer of data. This shift reopens a broad variety of system-level research questions concerning data placement, movement, processing and sharing. Importantly, the shift also opens the door to compelling new applications with significant industrial and societal impact in domains such as healthcare, manufacturing, transportation, public safety, energy, buildings, and telecommunications. Edge computing is broadly defined as a networked systems architectural approach in which compute and storage resources are placed at the network edge, in proximity to the mobile and IoT devices.

The proliferation of mobile and Internet-of-Things (IoT) devices, and their pervasiveness across nearly every sphere of our society, continues to raise questions about the architectures that organize tomorrow's compute infrastructure. At the heart of this trend is the data that will be generated as myriad devices and application services operate simultaneously to digitize a complex domain like a smart building or smart industrial facility. A key shift is from edge devices consuming data produced in the cloud to edge devices being a voluminous producer of data. This shift reopens a broad variety of system-level research questions concerning data placement, movement, processing and sharing. Importantly, the shift also opens the door to compelling new applications with significant industrial and societal impact in domains such as healthcare, manufacturing, transportation, public safety, energy, buildings, and telecommunications.

The mission of DOE's Fossil Energy R&D Program is to ensure the nation can continue to rely on traditional resources for clean, secure and affordable energy while enhancing environmental protection. The Carbon Capture program focuses on developing technologies to control emissions from either post-combustion units (e.g., pulverized coal) or pre-combustion (e.g., Integrated Gasification Combined Cycle, or IGCC). First Generation technologies (i.e. those that are currently being demonstrated or that are commercially available) exist, and Second Generation Technologies (i.e., those that include technology components currently in R&D and are expected to be ready for demonstration in the 2020-2025 timeframe) have shown potential for improvement towards an economic goal for cost of capture at less than $40/tonne, but are still cost prohibitive for broad deployment to the existing coal fleet. For Fiscal Year (FY) 2018, the Carbon Capture Program will solicit applications under this FOA to develop technologies in the area of pre-combustion carbon capture. Approaches that look at either hydrogen (H2) separation or carbon dioxide (CO2) separation will be accepted. The carbon capture technologies developed through this FOA will have direct application to coal gasification processes where coal derived synthesis gas or hydrogen are produced. Additionally, because gasification technology is often used to produce industrial chemicals, the technologies developed through this FOA will also be directly applicable to industrial gasifiers.

FRA's Office of Research, Development and Technology is charged with conducting research and development in support of improved railroad safety and national rail transportation policy. These activities support the objectives of the DOT, the mission critical needs of FRA, and the rail industry through technology development and demonstration, basic and applied research, and information exchange within the rail industry.

The mission of DOE's Fossil Energy R&D Program is to ensure the nation can continue to rely on traditional resources for clean, secure and affordable energy while enhancing environmental protection. The Carbon Capture program focuses on developing technologies to control emissions from either post-combustion units (e.g., pulverized coal) or pre-combustion (e.g., Integrated Gasification Combined Cycle, or IGCC). First Generation technologies (i.e. those that are currently being demonstrated or that are commercially available) exist, and Second Generation Technologies (i.e., those that include technology components currently in R&D and are expected to be ready for demonstration in the 2020-2025 timeframe) have shown potential for improvement towards an economic goal for cost of capture at less than $40/tonne, but are still cost prohibitive for broad deployment to the existing coal fleet. For Fiscal Year (FY) 2018, the Carbon Capture Program will solicit applications under this FOA to develop technologies in the area of pre-combustion carbon capture. Approaches that look at either hydrogen (H2) separation or carbon dioxide (CO2) separation will be accepted. The carbon capture technologies developed through this FOA will have direct application to coal gasification processes where coal derived synthesis gas or hydrogen are produced. Additionally, because gasification technology is often used to produce industrial chemicals, the technologies developed through this FOA will also be directly applicable to industrial gasifiers. Finally, as these technologies are successfully developed, they can represent an export opportunity to other countries that have a larger installed base of gasifiers than the U.S.

This Broad Agency Announcement (BAA) enhances the DPA Title III effort by providing to potential offerors information and procedures necessary to identify domestic industrial base projects, potentially meeting the DPA Title III criteria, by using the white paper and proposal formats. Project Announcements for a specific domestic industrial base shortfall, issued subsequent to this BAA, is the main method to initiate a call for white papers, leading to an evaluation and potential request for full proposals. Project Announcement #1 is included with this initial posting of the BAA. Consistent with the law, the DPA Title III Program has derived three broad Focus Areas for potential projects. The Focus Areas are: Sustainment of Critical Production, Commercialization of Research and Development Investments and Scaling of Emerging Technologies.

NineSigma, representing a global industrial manufacturer, invites proposals for engineering services for design and prototype of rugged power supplies for industrial applications.

The Process Separations program is part of the Chemical Process Systems cluster, which includes also 1) Catalysis; 2) Process Systems, Reaction Engineering, and Molecular Thermodynamics; and 3) Energy for Sustainability. The Process Separations program supports research focused on novel methods and materials for separation processes, such as those central to the chemical, biochemical, bioprocessing, materials, energy, and pharmaceutical industries. A fundamental understanding of the interfacial, transport, and thermodynamic behavior of multiphase chemical systems as well as quantitative descriptions of processing characteristics in the process-oriented industries is critical for efficient resource management and effective environmental protection. The program encourages proposals that address long standing challenges and emerging research areas and technologies, have a high degree of interdisciplinary work coupled with the generation of fundamental knowledge, and the integration of education and research. Research topics of particular interest include fundamental molecular-level work on: Design of scalable mass separating agents and/or a mechanistic understanding of the interfacial thermodynamics and transport phenomena that relate to purification of gases, chemicals, or water

Urban Air Mobility refers to the transport of passengers and goods through the air. Groundbreaking developments in autonomous flight, energy storage and electrical propulsion, and connected infrastructure have set the stage for what many are calling the biggest revolution in the skies since the jet engine was born. Ohio has a storied history in aviation and aerospace, and today remains a vibrant hub for this critical industry.  Join stakeholders spanning government, industry, and academia on Thursday February 27th, 2020 at The Ohio State University in Columbus, Ohio, to explore Ohio's opportunity and role in advancing Urban Air Mobility. The day-long symposium will feature panels and speakers which address various elements of the complex Urban Air Mobility (UAM) ecosystem, including: Defining UAM and its specific use cases Vehicle design, enabling technologies, and certification Operational challenges: airspace integration, cyber-security, and traffic management Infrastructure: planning, zoning, and financing (with Public-Private Partnerships) Leveraging Ohio's research, testing, manufacturing, and early use cases for UAM There will be plenty of opportunities for networking throughout the event, such as our lunch and post-event reception. Guests are also encouraged to reach out to the event organizing entities to schedule follow up discussions and/or site visits to tour Ohio's capability centers such as university research labs and the Ohio UAS Center.

The National Science Foundation (NSF) supports fundamental research and education in science and engineering. NSF's role results in new knowledge and tools as well as a capable, innovative workforce. These complementary building blocks of innovation have led to revolutionary technological advances and wholly new industries. NSF seeks to further develop and nurture a national innovation ecosystem built upon fundamental research that guides the output of scientific and engineering discoveries closer to the development of technologies, products, and services that benefit society. The goal of the NSF Innovation Corps (I-Corps) Program is to use experiential education to help entrepreneurial researchers reduce the time necessary to translate a promising idea from the laboratory bench to widespread implementation. In addition to accelerating technology translation, NSF seeks to reduce the risk associated with technology development conducted without insight into industry requirements and challenges.

The National Science Foundation Directorate for Engineering (NSF/ENG) invites the engineering research community to establish an organization that will serve to identify and develop bold and societally impactful new engineering research directions and thereby catalyze the engineering research community's pursuit of innovative, high-impact research. Specifically, NSF/ENG calls on the engineering research community to establish an Engineering Research Visioning Alliance (ERVA) that ENG will support to facilitate the articulation of compelling research visions that align with national and global challenges. This organization will be charged with obtaining and integrating input from all stakeholders with interest in engineering research, including academia, industry, societies, government agencies and the public. A reciprocal goal of the organization will be to communicate coordinated information on nascent opportunities and priorities in engineering research to these stakeholders. It is anticipated that through its activities the ERVA will strengthen connectivity across these diverse stakeholders, and increase coordination among engineering disciplinary communities. The ERVA should have membership/representation of academic, industrial and other stakeholders, and should be inclusive of all engineering disciplines. Through its proposed activities, the ERVA should provide the engineering community with a process for identifying future research challenges and enable the engineering research community to speak with a unified voice.

The National Science Foundation Directorate for Engineering (NSF/ENG) invites the engineering research community to establish an organization that will serve to identify and develop bold and societally impactful new engineering research directions and thereby catalyze the engineering research community's pursuit of innovative, high-impact research. Specifically, NSF/ENG calls on the engineering research community to establish an Engineering Research Visioning Alliance (ERVA) that ENG will support to facilitate the articulation of compelling research visions that align with national and global challenges. This organization will be charged with obtaining and integrating input from all stakeholders with interest in engineering research, including academia, industry, societies, government agencies and the public.A reciprocal goal of the organization will be to communicate coordinated information on nascent opportunities and priorities in engineering research to these stakeholders. It is anticipated that through its activities the ERVA will strengthen connectivity across these diverse stakeholders, and increase coordinationamong engineering disciplinary communities. The ERVA should have membership/representation of academic, industrial and other stakeholders, and should be inclusive of all engineering disciplines. Through its proposed activities, the ERVA should provide the engineering community with a process for identifying future research challenges and enable the engineering research community to speak with a unified voice.

ONR Global recognizes that international scientists and engineers conduct creative and novel research. This Global-X Challenge provides an opportunity for these international researchers to collaborate, generate revolutionary ideas and demonstrate these ideas will succeed. ONR Global invites outstanding international researchers to form multi-national, multidisciplinary teams to address one or more of these capability challenges. ONR Global will use existing online collaboration tools to help researchers to connect, collaborate and form teams. ONR Global will provide more information about collaboration forums during the Kick-off Webinar. Individual researchers may participate on more than one team. Teams are responsible for establishing nondisclosure agreements among team members, if necessary. All ONR Global and U.S. Federal employees are already covered by Federal laws requiring the protection of trade secrets and proprietary information. Researchers from academia and industry may participate. ONR Global expects, but does not require, that multi-national teams will consist of at least two research entities outside of the U.S., whether from academia, industry and/or the broad research community. Researchers from U.S. research entities may also participate, but are not required. As stated above, this Global-X Challenge is an opportunity specifically directed toward international researchers; therefore, ONR Global expects the majority of team members will be outside of the U.S. Each team shall designate a lead Principal Investigator (PI) whose research organization outside of the U.S. will submit the white paper or proposal, and that will distribute funding to co-PIs and other subrecipients. For a given project team, one award is made to the PI's institution. Only the PI's institution will be the prime awardee, and that institution is responsible for all aspects of the grant, including conditions on the use of funds and other terms and conditions of the gran

The High-Performance Computing for Manufacturing (HPC4Mfg) Program seeks qualified industry partners to participate in short-term, collaborative projects with the Department of Energy's (DOE's) national laboratories. Through support from the Advanced Manufacturing Office of the DOE Office of Energy Efficiency and Renewable Energy (EERE), selected industry partners will be granted access to High Performance Computing (HPC) facilities and experienced staff at DOE National Laboratories. The collaborations will address key challenges in U.S. manufacturing by apply modeling, simulation, and data analysis to the manufacturing of materials with the intent to improve energy efficiency, increase productivity, reduce cycle time, enable next-generation technologies, test control system algorithms, investigate intensified processes, lower energy cost, and accelerate innovation. Projects must demonstrate potential impact to energy efficiency in manufacturing and/or the development of new clean energy technologies with a potential for broad national impact. We solicit proposals in the following primary areas:

Join BioOhio and the Columbus chapter of the Healthcare Businesswomen's Association (HBA) for a FREE online event - our second Diversity in Bioscience & Healthcare event of 2020, on August 20 at 5 pm. The engaging discussion focuses on the importance of supporting STEM programming at an early age within under-represented communities to encourage careers within the science and healthcare industries. Our special guests include: Frederic Bertley, Ph.D., President & CEO, COSI Kirsten M. Ellenbogen, Ph.D., President & CEO, Great Lakes Science Center Kelly Lewis, Bioscience Technologies Program Instructor, Eastland-Fairfield Career and Technical Schools Lead by the talented Brooke Cartus, Director of Business Development and Senior Facilitator, ImprovEdge! Featuring networking opportunities during the event! This discussion will be held via Zoom. Login instructions are included in your registration confirmation email and reminder emails sent before the event. BioOhio and the Healthcare Business Women's Association (HBA) support all efforts to increase diversity and inclusion within the bioscience and healthcare industries and invite you to join us for our next discussion, Overcoming Obstacles in the Workplace: Making Work Accessible on November 14th, 2020. This event is brought to you by BioOhio in partnership with the Columbus chapter of the Healthcare Businesswomen's Association (HBA) and is made possible by the generous support of BioOhio members AtriCure and BIO.

The NIAID Radiation/Nuclear Countermeasures Development Program supports extramural research to develop safe and effective radiological/nuclear medical countermeasures for clinical use under emergency situations. This program spans basic through applied research. The role of the endovascular network in radiation injury pathogenesis is not well understood; however, the importance of this biological system in the observed multi-organ dysfunction and failure that occurs following radiation exposure has recently been established. The purpose of the Funding Opportunity Announcement (FOA) is to provide an opportunity for academic, industry and government laboratory researchers to address gaps in the understanding of the pathophysiology of radiation injury in the vasculature, and how this damage contributes to overall mortality following radiation exposure. This funding will also advance the development of post-exposure treatment approaches targeting the vascular endothelium, with the ultimate goal of licensure of candidate medical countermeasures by the Food and Drug Administration (FDA) for the radiation/nuclear public health emergency indication.

The NIAID Radiation/Nuclear Countermeasures Development Program supports extramural research to develop safe and effective radiological/nuclear medical countermeasures for clinical use under emergency situations. This program spans basic through applied research. The role of the endovascular network in radiation injury pathogenesis is not well understood; however, the importance of this biological system in the observed multi-organ dysfunction and failure that occurs following radiation exposure has recently been established. The purpose of the Funding Opportunity Announcement (FOA) is to provide an opportunity for academic, industry and government laboratory researchers to address gaps in the understanding of the pathophysiology of radiation injury in the vasculature, and how this damage contributes to overall mortality following radiation exposure. This funding will also advance the development of post-exposure treatment approaches targeting the vascular endothelium, with the ultimate goal of licensure of candidate medical countermeasures by the Food and Drug Administration (FDA) for the radiation/nuclear public health emergency indication.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program. 

The Science and Technology Directorate (S&T) is DHS's primary research and development (R&D) arm. S&T manages science and technology research, from development through transition, for the department's operational components and the nation's first responders. S&T's engineers, scientists and researchers work closely with industry and academic partners to ensure R&D investments address the high-priority needs of today and the growing demands of the future.The DHS Scientific Leadership Awards (SLA) program is one of several programs administered by the S&T Office of University Programs. Through the SLA program, OUP seeks to build a diverse, highly capable, technical workforce for the homeland security enterprise. This NOFO is soliciting applications from Minority Serving Intuitions (MSIs) to establish programs that relevant to S&T's mission within their institutions or MSI networks.

The Science and Technology Directorate (S&T) is DHS's primary research and development (R&D) arm. S&T manages science and technology research, from development through transition, for the department's operational components and the nation's first responders. S&T's engineers, scientists and researchers work closely with industry and academic partners to ensure R&D investments address the high-priority needs of today and the growing demands of the future.The DHS Scientific Leadership Awards (SLA) program is one of several programs administered by the S&T Office of University Programs. Through the SLA program, OUP seeks to build a diverse, highly capable, technical workforce for the homeland security enterprise. This NOFO is soliciting applications from Minority Serving Intuitions (MSIs) to establish programs that relevant to S&T's mission within their institutions or MSI networks.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program.