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The Long Term Research in Environmental Biology (LTREB) Program supports the generation of extended time series of data to address important questions in evolutionary biology, ecology, and ecosystem science. Research areas include, but are not limited to, the effects of natural selection or other evolutionary processes on populations, communities, or ecosystems; the effects of interspecific interactions that vary over time and space; population or community dynamics for organisms that have extended life spans and long turnover times; feedbacks between ecological and evolutionary processes; pools of materials such as nutrients in soils that turn over at intermediate to longer time scales; and external forcing functions such as climatic cycles that operate over long return intervals. The Program intends to support decadal projects. Funding for an initial, 5-year period requires submission of a preliminary proposal and, if invited, submission of a full proposal that includes a 15-page project description. Proposals for the second five years of support (renewal proposals) are limited to an eight-page project description and do not require a preliminary proposal. Continuation of an LTREB project beyond an initial ten year award will require submission of a new preliminary proposal that presents a new decadal research plan.?? Successful LTREB proposals address three essential components: A Decadal Research Plan that clearly articulates important questions that cannot be addressed with data that have already been collected, but could be answered if ten additional years of data were collected. This plan is not a research timeline or management plan. It is a concise justification for ten additional years of support in order to advance understanding of key concepts, questions, or theories in environmental biology.Core Data: LTREB proposals require that the author has studied a particular phenomenon or process for at least six years up to the present or for long enough to gene

The primary objective is to support scholarships for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The primary objective is to support fellowships for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The primary objective is to support faculty development for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The grants specifically target probationary, tenure-track faculty during the first 6 years of their career and new faculty hires in the following academic areas: Nuclear, Mechanical, Civil, Environmental, Electrical, Fire Protection, Geotechnical, Structural and Materials Sciences Engineering as well as Health Physics. The program provides support to enable newer faculty to enhance their careers as professors and researchers in the university department where employed.

The "Campus Cyberinfrastructure - Infrastructure, Innovation and Engineering (CC*IIE)" program invests in improvements and re-engineering at the campus level to support a range of data transfers supporting computational science and computer networks and systems research. The program also supports Network Integration activities tied to achieving higher levels of performance, reliability and predictability for science applications and distributed research projects. CC*IIE awards will be made in six areas. Data Driven Networking Infrastructure for the Campus and Researcher awards will be supported at up to $500,000 total for up to 2 years. Network Design and Implementation for Small Institutions awards will be supported at up to $350,000 total for up to two years. Network Integration and Applied Innovation awards will be supported at up to $1,000,000 total for up to 2 years. Identity and Access Management Integration awards will be supported at up to $300,000 total for up to two years. Campus CI Engineer awards will be made at up to $400,000 total for up to 2 years. Regional Coordination and Partnership in Advanced Networking awards will be made at up to $150,000 for up to 2 years.

This FOA relates to one of the initiatives of the SPARC (Stimulating Peripheral Activity to Relieve Conditions) Common Fund program titled: Use of Existing Market-Approved Technology for New Market Indications. By establishing effective public-private partnerships, this SPARC initiative allows supported investigators to have access to existing neuromodulation technology to explore new indications. A number of device manufacturers have entered into partnership agreements with the NIH to make their neuromodulation technology, consisting of implantable devices with recording and/or stimulation capabilities, available to SPARC's supported clinical investigators (see Device Portal for a list of companies and available technologies). The specific goal of this FOA is to promote the pre-clinical development of these technologies, in support of a new market indication, towards enabling an Investigational Device Exemption (IDE) submission for a future pilot clinical study. Awarded projects of this FOA that fully reach their pre-clinical testing milestones will be eligible for further support, subject to a subsequent FOA, to conduct a pilot clinical study. The expectation is that these pilot clinical studies will provide the initial proof-of-principle demonstrations in humans that will motivate the additional studies needed in pursuing FDA approval as a labeled indication.

This FOA relates to one of the initiatives of the SPARC (Stimulating Peripheral Activity to Relieve Conditions) Common Fund program titled: Use of Existing Market-Approved Technology for New Market Indications. By establishing effective public-private partnerships, this SPARC initiative allows supported investigators to have access to existing neuromodulation technology to explore new indications. A number of device manufacturers have entered into partnership agreements with the NIH to make their neuromodulation technology, consisting of implantable devices with recording and/or stimulation capabilities, available to SPARC's supported clinical investigators (see Device Portal for a list of companies and available technologies). The specific goal of this FOA is to promote the pre-clinical development of these technologies, in support of a new market indication, towards enabling an Investigational Device Exemption (IDE) submission for a future pilot clinical study. Awarded projects of this FOA that fully reach their pre-clinical testing milestones will be eligible for further support, subject to a subsequent FOA, to conduct a pilot clinical study. The expectation is that these pilot clinical studies will provide the initial proof-of-principle demonstrations in humans that will motivate the additional studies needed in pursuing FDA approval as a labeled indication.

The purpose of this Funding Opportunity Announcement (FOA) is to provide regional access for cryoelectron microscopy (cryoEM) laboratories to state-of-the-art data collection capabilities. NIGMS will support consortia of established and early stage investigator laboratories whose research has an established specialization in and dependence on cryoEM. These laboratories will coordinate with each other to share facilities and resources for direct electron detection. Consortia will consist of a host institution which already has a modern high-performing cryoEM installation and proven capabilities for high-resolution data collection, partnered with regional participating institutions. A consortium will support surplus capacity for cryoEM data collection (infrastructure and services) at the host institution and make it available as a resource for the participating regional institutions. Projects will support access for cryoEM laboratories at participating institutions to resources and services at host sites. Projects will (a) contribute to the fixed costs of maintaining the host facility and extend services in proportion to the resources dedicated to the regional users and (b) support access to the facility by the regional laboratories. The host institution need not already have an electron detector; this FOA can help fund acquisition of direct detection equipment. Support is limited to enabling the participating cryoEM laboratories to collect data and perform the initial stages of processing raw images, and does not include other research activities. Consortia will consist of a minimum of 3-5 institutions; award budgets will depend on the number and data collection needs of the regional participating cryoEM laboratories. This initiative is not intended to support service centers of the traditional type in which the host laboratory performs the cryoEM analysis for non-specialist collaborators.

The DOE Traineeship in Accelerator Science and Engineering provides support to address critical, targeted workforce development in fields of study that are currently supported by U.S. Department of Energy (DOE) research awards. Up to two Cooperative Agreements may provide funding to universities or consortia of universities for up to two years of tuition, stipend, and travel support to students enrolled in specific accelerator science and engineering degree programs, and to provide a modest topic-specific curriculum development and program administration support. Award term is expected to be up to five years, with the possibility of renewal for a second term. This program does not support lines of Research and Development (R&D). Support for accelerator R&D is provided through the High Energy Physics (HEP) General Accelerator R&D and Accelerator Stewardship programs, through accelerator R&D programs elsewhere in DOE, and by other federal agencies. This program is to assist domestic institutions of higher education in enhancing their graduate-level educational efforts to ensure that a diverse and highly trained future population of scientists is available to conduct cutting-edge research in the basic sciences. By training the scientists of the future, this program will ensure the continued vitality of U.S. scientific endeavors that will create knowledge for the public benefit.

The DOE Traineeship in Accelerator Science and Engineering provides support to address critical, targeted workforce development in fields of study that are currently supported by U.S. Department of Energy (DOE) research awards. Up to two Cooperative Agreements may provide funding to universities or consortia of universities for up to two years of tuition, stipend, and travel support to students enrolled in specific accelerator science and engineering degree programs, and to provide a modest topic-specific curriculum development and program administration support. Award term is expected to be up to five years, with the possibility of renewal for a second term. This program does not support lines of Research and Development (R&D). Support for accelerator R&D is provided through the High Energy Physics (HEP) General Accelerator R&D and Accelerator Stewardship programs, through accelerator R&D programs elsewhere in DOE, and by other federal agencies.

As the largest video, high-speed Internet, and phone provider to residential customers, Comcast Cable is committed to supporting external technical research and open source software development. Over the long term, this can lead to critical insights and advancements that can positively benefit consumers by delivering innovative new generations of products faster than ever before. The Comcast Innovation Fund offers funding for researchers at leading academic institutions and elsewhere to support research that is of mutual interest to Comcast and the research community. It also provides funding to support open source software development. While Comcast has supported this kind of work for many years, we are now doing so in a more strategic way. RESEARCH GRANTS Research Grants can be either general or targeted. A general research grant provides an unrestricted award of funds to support researchers, usually at colleges and universities. These grants are focused on supporting excellent technical research in a wide variety of fields that are relevant to the broadband industry and/or to Comcast specifically. In contrast, a targeted research grant is more narrowly tailored and typically study more specific issues. In either case, applicants are encouraged to consider grants that may have a cooperative focus, whereby researchers can be matched with a Comcast engineering liaison who will be involved with the research. Applicants for these grants may be organizations, academic institutions, or individuals.

The Geotechnical Engineering and Materials Program (GEM) supports fundamental research in soil and rock mechanics and dynamics in support of physical civil infrastructure systems. Also supported is research on improvement of the engineering properties of geologic materials for infrastructure use by mechanical, biological, thermal, chemical, and electrical processes. The Program supports the traditional areas of foundation engineering, earth structures, underground construction, tunneling, geoenvironmental engineering, and site characterization, as well as the emerging area of bio-geo engineering, for civil engineering applications, with emphasis on sustainable geosystems. Research related to the geotechnical engineering aspects of geothermal energy and geothermal heat pump systems is also supported. The GEM program encourages knowledge dissemination and technology transfer activities that can lead to broader societal benefit and implementation for provision of physical civil infrastructure. The Program also encourages research that explores and builds upon advanced computing techniques and tools to enable major advances in Geotechnical Engineering.

Supported by the NIH Common Fund (Common Fund) Science of Behavior Change (SOBC) Program, this Funding Opportunity Announcement (FOA) solicits competitive revision (formerly known as a competitive supplement) applications to NIH-supported clinical trials awarded as research project R34 grants. The goal of the SOBC Program is to advance a mechanisms-focused, experimental medicine approach to behavior change research. Funded projects in the SOBC Research Network (https://commonfund.nih.gov/behaviorchange/fundedresearch) have developed experimental manipulations, assays, and/or measures (hereafter referred to as assays for brevity) to support an experimental medicine approach to behavior change research. The SOBC Measures Repository is accessible from the SOBC Research Network Open Science Framework (OSF) page at https://osf.io/zp7b4. The goal of this FOA is to accelerate the adaptation, validation, and translation of SOBC Research Network assays for use in ongoing clinical trials. This FOA calls for the integration of SOBC Research Network assays into active NIH-supported clinical trials of drugs, devices, procedures, or behavior modifications. As such, the active NIH-supported clinical trial used to respond to this FOA does not have to be a behavior change trial or identify behavior change as a primary outcome. The integration of SOBC Research Network assays into ongoing clinical trials will accelerate the development of interventions and experimental manipulations that have been shown to engage specific mechanisms of behavior change and the development of assays that verify engagement of those behavior change targets.

The Campus Cyberinfrastructure (CC*) program invests in coordinated campus-level networking improvements, innovation, integration, and engineering for science applications and distributed research projects. Learning and workforce development (LWD) in cyberinfrastructure is explicitly addressed in the program. Science-driven requirements are the primary motivation for any proposed activity. CC* awards will be supported in four program areas: (1)Data Driven Networking Infrastructure for the Campus and Researcher awards will be supported at up to $500,000 total for up to 2 years; (2) Network Design and Implementation for Small Institutions awards will be supported at up to $750,000 total for up to 2 years; (3) Network Integration and Applied Innovation awards will be supported at up to $1,000,000 total for up to 2 years; and (4) Network Performance Engineering and Outreach awards will be supported at up to $3,500,000 total for up to 4 years.

The Human Cell Atlas (HCA) is a global effort to create a reference map of all cell types in the human body. The Chan Zuckerberg Initiative and the Helmsley Charitable Trust are pleased to announce continued support for the Human Cell Atlas by collaborating on two new funding mechanisms that the community can access through a single application portal. The Chan Zuckerberg Initiative seeks to continue the work of the HCA community with a focus on interdisciplinary work and collaboration through the formation of 3 year Seed Networks. The Helmsley Charitable Trust welcomes applications that will construct a detailed atlas of the human gut. Project Specifications This Request for Applications (RFA) seeks to support the continued growth of nascent projects and to incubate new networks. The Seed Networks should generate new tools, open source analysis methods, and significant contributions of diverse data types to the Human Cell Atlas Data Coordination Platform. Applications should have a primary focus on the healthy tissues that will contribute to a reference atlas. Seed Networks Seed Networks should consist of at least three principal investigators, including at least one computational biologist or software engineer, together with additional computational biologists, engineers, experimental biologists, and/or physicians. CZI Seed Networks aim to support foundational tools and resources for the HCA and will not require a gut component in the application. CZI Seed Network Grants have four overarching scientific goals: - Build and support networks of collaborating scientists and engineers; - Contribution of high-quality data to v1.0 of the HCA; - Development of new technologies and benchmark data sets, particularly those anchored in spatial as well as molecular information; - Support of computational biology within the Human Cell Atlas community.

The FOA will support early-stage research that spans the Solar Energy Technologies Office (SETO) portfolio, seeking to advance both solar photovoltaic (PV) and concentrating solar thermal power (CSP) technologies and to facilitate the swift integration of those technologies into the nation's electricity grid. It also is designed to support efforts that prepare the workforce for the solar industry's future needs. The FOA is organized into the following high level Topic Areas: Topic 1: Advanced Solar Systems Integration Technologies describes SETO research priorities in the seamless integration of high penetrations of solar energy onto the nation's electricity grid. Topic 2: Concentrating Solar Thermal Power Research and Development describes SETO research priorities that support solar technologies that focus sunlight to generate and store high-temperature heat for electricity generation and other end uses. Topic 3: Photovoltaic Research and Development describes SETO research priorities that support the further development of photovoltaic technologies that improve system reliability, annual energy yield, demonstrate performance of novel PV devices and develop new PV materials. Topic 4: Improving and Expanding the Solar Industry through Workforce Initiatives describes SETO research priorities that support solar workforce development.

The Geotechnical Engineering and Materials Program (GEM) supports fundamental research in soil and rock mechanics and dynamics in support of physical civil infrastructure systems. Also supported is research on improvement of the engineering properties of geologic materials for infrastructure use by mechanical, biological, thermal, chemical, and electrical processes. The Program supports the traditional areas of foundation engineering, earth structures, underground construction, tunneling, geoenvironmental engineering, and site characterization, as well as the emerging area of bio-geo engineering, for civil engineering applications, with emphasis on sustainable geosystems. Research related to the geotechnical engineering aspects of geothermal energy and geothermal heat pump systems is also supported. The GEM program encourages knowledge dissemination and technology transfer activities that can lead to broader societal benefit and implementation for provision of physical civil infrastructure. The Program also encourages research that explores and builds upon advanced computing techniques and tools to enable major advances in Geotechnical Engineering.

The Engineering Design and Systems Engineering (EDSE) program supports fundamental research into the basic processes and phenomena of engineering design and systems engineering. The program seeks proposals leading to improved understanding about how processes, organizational structure, social interactions, strategic decision making, and other factors impact success in the planning and execution of engineering design and systems engineering projects. It also supports advances pertaining to engineering design and systems engineering in areas that include, but are not limited to, decision making under uncertainty, including preference and demand modeling; problem decomposition and decision delegation; applications of reverse game theory (mechanism design); computer-aided design; design representation; system performance modeling and prediction; design optimization; uncertainty quantification; domain- or concern-specific design methods; and advanced computational techniques for supporting effective human cognition, decision making, and collaboration. Competitive proposals for novel methods will include a plan to evaluate rigorously the effectiveness and performance of the proposed approach. The EDSE program encourages multidisciplinary collaborations of experts in design and systems engineering with experts in other domains. Of particular interest is research on the design of engineering material systems that leverages the unique aspects of a particular material system to realize advanced design methods that are driven by performance metrics and incorporate processing/manufacturing considerations. The EDSE program does not support the development of ad-hoc approaches that lack grounding in theory, nor does it support design activities that do not advance scientific knowledge about engineering design or systems engineering. Prospective investigators are encouraged to discuss research ideas and project scope with the Program Director in advance of proposal preparation and

The goal of the RCN program is to advance a field or create new directions in research or education by supporting groups of investigators to communicate and coordinate their research, training and educational activities across disciplinary, organizational, geographic and international boundaries. The RCN program provides opportunities to foster new collaborations, including international partnerships, and address interdisciplinary topics. Innovative ideas for implementing novel networking strategies, collaborative technologies, training, broadening participation, and development of community standards for data and meta-data are especially encouraged. RCN awards are not meant to support existing networks; nor are they meant to support the activities of established collaborations RCN awards also do not support primary research. Rather, the RCN program supports the means by which investigators can share information and ideas, coordinate ongoing or planned research activities, foster synthesis and new collaborations, develop community standards, and in other ways advance science and education through communication and sharing of ideas.

The Campus Cyberinfrastructure (CC*) program invests in coordinated campus-level networking improvements, innovation, integration, and engineering for science applications and distributed research projects. Learning and workforce development (LWD) in cyberinfrastructure is explicitly addressed in the program. Science-driven requirements are the primary motivation for any proposed activity. CC* awards will be supported in four program areas: 1. Data Driven Networking Infrastructure for the Campus and Researcher awards will be supported at up to $500,000 total for up to 2 years; 2. Network Design and Implementation for Small Institutions awards will be supported at up to $750,000 total for up to 2 years; 3. Network Integration and Applied Innovation awards will be supported at up to $1,000,000 total for up to 2 years; and 4. Network Performance Engineering and Outreach awards will be supported at up to $3,500,000 total for up to 4 years.

The goal of the Environmental Sustainability program is to promote sustainable engineered systems that support human well-being and that are also compatible with sustaining natural (environmental) systems.  These systems provide ecological services vital for human survival.  Research efforts supported by the program typically consider long time horizons and may incorporate contributions from the social sciences and ethics. The program supports engineering research that seeks to balance society's need to provide ecological protection and maintain stable economic conditions.

The goal of the Environmental Sustainability program is to promote sustainable engineered systems that support human well-being and that are also compatible with sustaining natural (environmental) systems.  These systems provide ecological services vital for human survival.  Research efforts supported by the program typically consider long time horizons and may incorporate contributions from the social sciences and ethics. The program supports engineering research that seeks to balance society's need to provide ecological protection and maintain stable economic conditions.

The International Research Network Connections (IRNC) program supports high-performance network connectivity required by international science and engineering research and education collaborations involving the NSF research community. NSF expects to make 1-2 awards to link U.S. research networks with peer networks in Europe and Africa and leverage existing international network connectivity. High-performance network connections funded by this program are intended to support science and engineering research and education applications, and preference will be given to solutions that provide the best economy of scale and demonstrate the ability to support the largest communities of interest with the broadest services. Funded projects will assist the U.S. research and education community by enabling state-of-the-art international network services and access to increased collaboration and data services. Through extended international network connections, additional research and production network services will be enabled, complementing those currently offered or planned by domestic research networks.

The International Research Network Connections (IRNC) program supports high-performance network connectivity required by international science and engineering research and education collaborations involving the NSF research community. NSF expects to make 1-2 awards to link U.S. research networks with peer networks in Europe and Africa and leverage existing international network connectivity. High-performance network connections funded by this program are intended to support science and engineering research and education applications, and preference will be given to solutions that provide the best economy of scale and demonstrate the ability to support the largest communities of interest with the broadest services. Funded projects will assist the U.S. research and education community by enabling state-of-the-art international network services and access to increased collaboration and data services. Through extended international network connections, additional research and production network services will be enabled, complementing those currently offered or planned by domestic research networks.

The Office of Energy Efficiency and Renewable Energy (EERE) intends to issue, on behalf of the Wind and Water Power Technologies Office, a Funding Opportunity Announcement- FOA- entitled Marine and Hydrokinetic Energy Conversion and Environmental Monitoring Technology Advancement. This FOA is soliciting applications that propose projects supporting the marine and hydrokinetic MHK industry in two Topic Areas. Topic Area 1 will help advance wave and current energy- ocean, tidal, river- technologies by supporting projects that integrate advanced MHK components into system designs and then demonstrate the improved systems in full-scale open-water tests. Topic Area 2 will support the innovation, testing and validation of instrumentation for monitoring potential environmental impacts of MHK devices. The complete Notice of Intent can be viewed on the EERE Exchange website - https://eere-exchange.energy.gov This is a Notice of Intent only. EERE may issue a FOA as described herein, may issue a FOA that is significantly different from the FOA described herein, or EERE may not issue a FOA at all. NO APPLICATIONS WILL BE ACCEPTED THROUGH THIS NOI. Please do not submit questions or respond to this NOI. Prospective applicants to the FOA should begin developing partnerships, formulating ideas, and gathering data in anticipation of the issuance of this FOA. It is anticipated that this FOA will be posted to the EERE Exchange website in the near term.

The Office of Energy Efficiency and Renewable Energy (EERE) intends to issue, on behalf of the Wind and Water Power Technologies Office, a Funding Opportunity Announcement- FOA- entitled Marine and Hydrokinetic Energy Conversion and Environmental Monitoring Technology Advancement. This FOA is soliciting applications that propose projects supporting the marine and hydrokinetic MHK industry in two Topic Areas. Topic Area 1 will help advance wave and current energy- ocean, tidal, river- technologies by supporting projects that integrate advanced MHK components into system designs and then demonstrate the improved systems in full-scale open-water tests. Topic Area 2 will support the innovation, testing and validation of instrumentation for monitoring potential environmental impacts of MHK devices. The complete Notice of Intent can be viewed on the EERE Exchange website - https://eere-exchange.energy.gov This is a Notice of Intent only. EERE may issue a FOA as described herein, may issue a FOA that is significantly different from the FOA described herein, or EERE may not issue a FOA at all. NO APPLICATIONS WILL BE ACCEPTED THROUGH THIS NOI. Please do not submit questions or respond to this NOI. Prospective applicants to the FOA should begin developing partnerships, formulating ideas, and gathering data in anticipation of the issuance of this FOA. It is anticipated that this FOA will be posted to the EERE Exchange website in the near term.