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The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is aimed at revolutionizing neuroscience through development and application of innovative technologies to map neural circuits, monitor and modulate their activity, and understand how they contribute to thoughts, sensations, emotions and behavior. NIH has issued a variety of Funding Opportunity Announcements (FOAs) that will support projects that apply technologies to understand neural circuit function in the context of specific circuits, resulting in a diverse portfolio of research into the fundamental biology of nervous system function. The purpose of this announcement is to notify the research community that NIH welcomes BRAIN Initiative applications targeting central nervous system nociceptive and pain circuits, as appropriate to the goals and requirements of specific BRAIN Initiative FOAs. Pain conditions represent an important public health problem and NIH continues to support research into pain pathologies through normal Institute and Center appropriations. However, pain and nociception are also components of normal nervous system function, and the BRAIN Initiative is committed to understanding pain circuits along with brain circuits underlying other sensory, motor, cognitive and emotional functions. It is expected that the unique opportunities of the BRAIN Initiative will enable production of detailed maps of pain circuits, and the adoption of powerful new tools for monitoring and modulating pain circuit activity, leading to significant advances in the understanding of pain and nociception. For a list of past and open BRAIN Initiative FOAs, see https://braininitiative.nih.gov/funding/.

The FY17 KCRP Concept Award supports highly innovative, untested, potentially groundbreaking novel concepts in kidney cancer. The Concept Award is not intended to support an incremental progression of an already established research project but, instead, allows Principal Investigators (PIs) the opportunity to pursue serendipitous observations. Preliminary data are not allowed. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for investigation relevant to active duty Service members, Veterans, other military beneficiaries, and the American public. Applications must describe how the new idea will enhance the existing knowledge of kidney cancer or develop an innovative and novel course of investigation. Research completed through a Concept Award may generate sufficient preliminary data to enable the PI to prepare an application for future research. The anticipated direct costs budgeted for the entire period of performance for an FY17 KCRP Concept Award will not exceed $75,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

The DOE Traineeship in Accelerator Science and Engineering provides support to address critical, targeted workforce development in fields of study that are currently supported by U.S. Department of Energy (DOE) research awards. Up to two Cooperative Agreements may provide funding to universities or consortia of universities for up to two years of tuition, stipend, and travel support to students enrolled in specific accelerator science and engineering degree programs, and to provide a modest topic-specific curriculum development and program administration support. Award term is expected to be up to five years, with the possibility of renewal for a second term. This program does not support lines of Research and Development (R&D). Support for accelerator R&D is provided through the High Energy Physics (HEP) General Accelerator R&D and Accelerator Stewardship programs, through accelerator R&D programs elsewhere in DOE, and by other federal agencies. This program is to assist domestic institutions of higher education in enhancing their graduate-level educational efforts to ensure that a diverse and highly trained future population of scientists is available to conduct cutting-edge research in the basic sciences. By training the scientists of the future, this program will ensure the continued vitality of U.S. scientific endeavors that will create knowledge for the public benefit.

The 2012 Moving Forward for Progress in the 21st Century Act (MAP-21) provides a framework for the National Park Service and Federal Aviation Administration to work together to develop incentives for Grand Canyon air tour operators using quiet technology aircraft without increasing noise at the park. Data gathered and analyzed under this project will aid planning for overflights management, as well as improve wilderness character in Grand Canyon National Park which will benefit the public both within and beyond the borders of the park.

Alex's Lemonade Stand Foundation, a nonprofit foundation that has evolved from a young cancer patient's front yard lemonade stand to a national foundation for childhood cancer, awards grants designed to fill critical voids in current pediatric cancer research. Through its Innovation Grants program, the foundation awards two-year grants of up to $250,000 in support of researchers with a novel approach to pediatric oncology investigation. This can include a change in research direction and/or an innovative new idea that moves away from an investigator's prior research but has potential impact for childhood cancers. Innovation Grants will support research proposals to be carried out by investigators who are already established, have a track record of peer-reviewed publications, and can demonstrate evidence of successfully competing for extramural funding. To be eligible, applicants must possess a degree at the MD, MD/PhD or PhD level and hold a faculty appointment at an academic institution.

Founded in 1996, the Marsha Rivkin Center for Ovarian Cancer Research provides funding for multiple efforts, including funding for innovative research pilot studies, scholar grants to up-and-coming investigators to encourage their careers in ovarian cancer research, public early detection screening for ovarian cancer, and nationally and internationally attended research symposia focused on ovarian cancer. To advance this mission, the center has issued a Call for Applications for its 2018 Scientific Scholar Awards. Through the program, the center will award grants of up $120,000 over two years to promising laboratory and clinical scientists interested in pursuing a career as an independent investigator in ovarian cancer research. Funds are for direct costs only; institutional overhead and indirect costs are not covered by the award. Eligible applicants must have an MD, PhD, or equivalent degree with career goals focused on ovarian cancer, and clinicians must have completed their residency. All applicants should be at the postdoc/fellow, instructor, research assistant, or assistant professor level, with no more than three to four years in any of these positions. Established outstanding scientists without prior focus in ovarian cancer but looking to focus in this area are also encouraged to apply.

This BAA sets forth basic and applied scientific research areas of interest of the Army Research Laboratory. This BAA is issued under paragraph 6.102(d)(2) of the Federal Acquisition Regulation (FAR), which provides for the competitive selection of basic and applied research proposals, and 10 U.S.C. 2358, 10 U.S.C. 2371, and 10 U.S.C. 2371b, which provide the authorities for issuing awards under this announcement for basic and applied research. The definitions of basic and applied research may be found at 32 Code of Federal Regulations (CFR) 22.105.Proposals submitted in response to this BAA and selected for award are considered to be the result of full and open competition and in full compliance with the provision of Public Law 98- 369, "The Competition in Contracting Act of 1984" and subsequent amendments.

This BAA is intended to solicit extramural research and development ideas, and is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in Federal Acquisition Regulation 6.102(d) (2) and 35.016. This announcement provides a general description of USSOCOM's research areas of interest, general information, evaluation and selection criteria, and proposal/application preparation instructions. In accordance with FAR 6.102, projects funded under this announcement must be for basic and applied research and that part of development not related to the development of a specific system or hardware procurement. Projects must be for scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding. Projects that are for the development of a specific system or hardware procurement will not be considered. The selection process is highly competitive and the quantity of meaningful proposal/applications (both pre-proposal/pre-applications and full proposal/full applications) typically received exceed the number of awards that available funding can support. This BAA provides a general description of USSOCOM's research and development programs, including research areas of interest, evaluation and selection criteria, pre-proposal/pre-application and full proposal/application preparation instructions, and general administrative information. Specific submission information and additional administrative requirements can be found in the document titled "General Submission Instructions" available in Grants.gov along with this BAA.

The Fellowship Program expects to award two new Ph.D. Fellowships each year to students who are interested in careers related to the development and implementation of quantitative methods for assessing the economics of the conservation and management of living marine resources. Fellows will work on thesis problems of public interest and relevance to National Marine Fisheries Service (NMFS) under the guidance of NMFS mentors at participating NMFS Science Centers or Offices. The NMFS-Sea Grant Fellowship in Marine Resource Economics meets NOAA's Healthy Oceans goal of "Marine fisheries, habitats, biodiversity sustained with healthy and productive ecosystems." The expected annual award per Fellow will be $46,000 (Federal plus matching funds), which is funded jointly by NOAA Fisheries and Sea Grant.

This Funding Opportunity Announcement (FOA) encourages applications for research awards that are focused on the use of the Osteoarthritis Initiative (OAI) database, clinical data and images. This FOA seeks to expand the use of these resources by investigators in the broader research community. The publication of this FOA to the research community indicates to investigators and peer reviewers the importance that the NIAMS and others have placed on the use of the OAI resources.

Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (NSF INCLUDES) is a comprehensive national initiative designed to enhance U.S. leadership in science, technology, engineering and mathematics (STEM) discoveries and innovations focused on NSF's commitment to diversity, inclusion, and broadening participation in these fields. The initiative is developing a National Network composed of NSF INCLUDES Design and Development Launch Pilots, NSF INCLUDES Alliances, NSF-funded broadening participation projects, other relevant NSF-funded projects, scholars engaged in broadening participation research, and other organizations that support the development of talent from all sectors of society to build the STEM workforce. To facilitate the Network's operation, the program is soliciting proposals for a NSF INCLUDES Coordination Hub that will drive and support the work of the NSF INCLUDES National Network over the lifecycle of the initiative by: (a) promoting the NSF INCLUDES guiding vision and strategy; (b) developing a collaborative infrastructure to support the activities of the various entities partnering in the NSF INCLUDES National Network; (c) fostering progress among Network partners toward shared models, measurement practices, and evaluation criteria; (d) communicating the discoveries of and generating enthusiasm for the NSF INCLUDES National Network; and (e) advancing the expansion and scale of the NSF INCLUDES National Network by connecting expertise from multiple sectors and other private and public funders.

The Science and Technology Centers (STC): Integrative Partnerships program supports exceptionally innovative, complex research and education projects that require large-scale, long-term awards. STCs focus on creating new scientific paradigms, establishing entirely new scientific disciplines and developing transformative technologies which have the potential for broad scientific or societal impact. STCs conduct world-class research through partnerships among institutions of higher education, national laboratories, industrial organizations, other public or private entities, and via international collaborations, as appropriate. They provide a means to undertake potentially groundbreaking investigations at the interfaces of disciplines and/or highly innovative approaches within disciplines. STCs may involve any area of science and engineering that NSF supports. STC investments support the NSF vision of creating and exploiting new concepts in science and engineering and providing global leadership in research and education.

The goal of the interagency Smartand Connected Health (SCH): Connecting Data, People and Systems program is to accelerate the development and integration of innovative computer and information scienceand engineering approaches to support the transformation of health and medicine. Approaches that partner technology-based solutions with biomedical and biobehavioral research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next-generation multidisciplinary science that encourages existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as networking, pervasive computing, advanced analytics, sensor integration, privacy and security, modeling of socio-behavioral and cognitive processes and system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, barriers to change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems and an aging population.Such solutions demand multidisciplinary teams ready to address issues ranging from fundamental science and engineering to medical and public health practice.

The proliferation of mobile and Internet-of-Things (IoT) devices, and their pervasiveness across nearly every sphere of our society, continues to raise questions about the architectures that organize tomorrow’s compute infrastructure. At the heart of this trend is the data that will be generated as myriad devices and application services operate simultaneously to digitize a complex domain like a smart building or smart industrial facility. A key shift is from edge devices consuming data produced in the cloud to edge devices being a voluminous producer of data. This shift reopens a broad variety of system-level research questions concerning data placement, movement, processing and sharing. Importantly, the shift also opens the door to compelling new applications with significant industrial and societal impact in domains such as healthcare, manufacturing, transportation, public safety, energy, buildings, and telecommunications. Edge computing is broadly defined as a networked systems architectural approach in which compute and storage resources are placed at the network edge, in proximity to the mobile and IoT devices.

The proliferation of mobile and Internet-of-Things (IoT) devices, and their pervasiveness across nearly every sphere of our society, continues to raise questions about the architectures that organize tomorrow's compute infrastructure. At the heart of this trend is the data that will be generated as myriad devices and application services operate simultaneously to digitize a complex domain like a smart building or smart industrial facility. A key shift is from edge devices consuming data produced in the cloud to edge devices being a voluminous producer of data. This shift reopens a broad variety of system-level research questions concerning data placement, movement, processing and sharing. Importantly, the shift also opens the door to compelling new applications with significant industrial and societal impact in domains such as healthcare, manufacturing, transportation, public safety, energy, buildings, and telecommunications.

The Global Engagement Center (GEC), an interagency entity within the U.S. Department of State, invites organizations that can implement programming to counter foreign state and non-state propaganda and disinformation efforts aimed at undermining United States national security interests to submit applications by April 11, 2018. All submissions or applications will be reviewed against the evaluation criteria outlined below. GEC expects to make multiple awards with a floor of $200,000 and a ceiling of $500,000 for each, constituting a planned total award volume of approximately $5,000,000. GEC reserves the right to award more or less funding or no funding at all as it deems in the best interest of the government. U.S.-based and foreign non-profit and non-governmental organizations (NGO), public international organizations (PIO), media outlets, for-profit entities, and institutions of higher education are eligible to apply by submitting an application as described in this announcement.

In this Addendum under the STIP APS, USAID/LAB aims to accelerate LMIC capacity for high-level science, technology, and innovation by supporting partnerships between U.S. HEIs, LMIC HEIs, and other relevant public or private sector partners.

The U.S. Department of Energy seeks to understand the key technical and other barriers that may prevent long-term access to low-cost water supplies that could be best addressed through challenges and prize competitions. For the purposes of this Request for Information (RFI), challenges and prize competitions are tools and approaches the Federal government and others can use to engage a broad range of stakeholders, including the general public, in developing solutions to difficult problems. Challenges and prize competitions rely on competitive structures to drive innovation among participants and usually offer rewards (financial and/or other) to winners and/or finalists. DOE may use the information provided through this RFI to develop challenges and prize competitions to address key water issues. This RFI is not designed to solicit input on DOE's broader R&D efforts on affordable water. The purpose of this Request for Information (RFI) is to gather feedback from stakeholders prior to DOE potentially issuing a Funding Opportunity Announcement (FOA). This RFI is not a FOA; therefore, DOE is not accepting applications at this time. All responses to this RFI must be provided as an attachment (in Microsoft Word format) to an e-mail message addressed to waterprizerfi@ee.doe.gov. Responses must be received no later than 5:00 pm EDT on May 14, 2018. The full content of the announcement can be found on the EERE Exchange website at https://eere-exchange.energy.gov/

The USAFA is seeking unclassified research white papers and proposals that do not contain proprietary information. If proprietary information is submitted it is the offerors' responsibility to mark the relevant portions of their proposal as specified in USAFA-BAA-2015. CAStLE performs a range of structural integrity research tasks in support of multiple Government, academic and commercial sponsors. Among these pursuits, CAStLE engages in a wide range of corrosion engineering and material science research efforts, with more emphasis on applied research, and that part of development not related to a specific system or hardware procurement. Current CAStLE research strengths include: high temperature materials development; advanced barrier coatings; static strength, static stability design, corrosion modeling, prevention and control; validation testing, analysis and methods development; computational structural and fracture mechanics; failure analysis, flight data acquisition system development, installation, maintenance and data analysis; structural risk analysis, and support of the USAF Aircraft Structural Integrity Program (ASIP). The interaction between corrosion and cracking damage mechanisms and their effect on the structural integrity has been a long-standing interest of CAStLE. There is Department of Defense (DoD) level interest in material degradation in structures-to include corrosion, cracking and other service-related damage mechanisms. The DoD level material degradation interest is the subject of this CALL, while also serving a dual public purpose.

The NIH Research Evaluation and Commercialization Hub (REACH) program is envisioned as a partnership program between NIH and the qualifying research institutions to accelerate the creation of small businesses and the transition of discoveries originating from academic research into products that improve health. REACH Hubs will foster the advancement of therapeutics, preventatives, diagnostics, devices, and tools in a manner consistent with business case development, that address the needs of patients and public health.