Group items tagged

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to support screening of target-based pharmaceutical libraries to identify candidate therapeutics against select eukaryotic pathogens and subsequent preclinical development activities.

Pharmaceutical blister packages often have moisture and oxygen barrier requirements to maintain the efficacy of the drug they contain. Traditional barrier materials used today are PCTFE, EVOH, PVDC, PVC, COC, and combinations thereof. Klockner Pentaplast Films is seeking a thermoformable solution that can be made into blister packs that protects pharmaceuticals from moisture and oxygen. Although the use of glass bottles meets the technical specs of this RFP, studies have shown that compliance to medication instructions increases when patients and consumers use blister packs. The technology must: * Be a material, or a technology that enables the modification of a material, to achieve ALL of the following properties: - Can be made into a thermoformable film - Provides the moisture barrier equivalence of 0.015 g-mil/100 in²-day - Provides an oxygen barrier equivalence of 0.005 cm³-mil/100 in²-day - Be approved (or approvable) for food safety by the FDA - Contains no halogens *Other properties that are highly desired but not required for this application: - Optically clear - Can be recycled in traditional recycling streams - Contains mostly bio-based, natural, or sustainable materials

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to support screening of target-based pharmaceutical libraries to identify candidate therapeutics against select eukaryotic pathogens and subsequent preclinical development activities.

This Funding Opportunity Announcement (FOA) encourages applications for Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54s). The mission of the CounterACT program is to foster and support research and development of new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare agents, toxic industrial chemicals, pharmaceutical-based agents, and pesticides. The scope of the research includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy consistent with the product's intended use in humans. For applicants submitting U54 renewal applications, research under this FOA should culminate in an optimized lead compound ready for advanced development. The Centers will contain at least three research projects supported by an administrative core, up to three optional scientific cores, and a research education core. Each research project must include milestones that create discrete go or no-go decision points in a progressive translational study plan.

The Process Separations program is part of the Chemical Process Systems cluster, which includes also 1) Catalysis; 2) Process Systems, Reaction Engineering, and Molecular Thermodynamics; and 3) Energy for Sustainability. The Process Separations program supports research focused on novel methods and materials for separation processes, such as those central to the chemical, biochemical, bioprocessing, materials, energy, and pharmaceutical industries. A fundamental understanding of the interfacial, transport, and thermodynamic behavior of multiphase chemical systems as well as quantitative descriptions of processing characteristics in the process-oriented industries is critical for efficient resource management and effective environmental protection. The program encourages proposals that address long standing challenges and emerging research areas and technologies, have a high degree of interdisciplinary work coupled with the generation of fundamental knowledge, and the integration of education and research. Research topics of particular interest include fundamental molecular-level work on: Design of scalable mass separating agents and/or a mechanistic understanding of the interfacial thermodynamics and transport phenomena that relate to purification of gases, chemicals, or water

Ohio is home to approximately 26,000 individuals living with paralysis as a result of a Spinal Cord Injury (SCI). According to the National SCI Statistical Center 66% of those individuals remain unemployed with each expected to manage lifetime healthcare costs of $1-3M. This represents a significant cost to the state and also imposes a severe burden on the quality of life for those living with this impairment. While there is research in pursuit of improved treatments to ameliorate the effects of paralysis, the field is significantly underfunded relative to similarly sized patient populations or disease with similar lifetime healthcare costs. While the scientific disciplines of neuroscience and biomedical engineering are making progress toward the development of new treatments, there is a lack of systematic and especially localized effort to guide these advances representative of the various stakeholders. The research funded through this process is specifically targeted to advance and accelerate the development of innovative treatments, product innovation and rehabilitative efforts that lead to the functional improvement of people living with spinal cord injuries. Research topics may include, but are not limited to, discovery science, pharmaceutical development, medical device design and implementation, and the development of novel rehabilitative approaches and techniques.

ENTELLIGENCE, in partnership with Actelion Pharmaceuticals US, supports basic science, translational, and clinical research in the field of cardiopulmonary medicine. The program provides opportunities for individual young investigators to promote quality medical care and enhance patients' lives by supporting research in pulmonary hypertension. To that end, ENTELLIGENCE is accepting applications for its thirteenth annual Young Investigator grant program. Established in 2005, the program provides opportunities for promising young investigators to promote quality medical care and enhance patients' lives by supporting research (basic science, clinical, or translational) in the area of pulmonary hypertension specifically related to expanding knowledge of pulmonary vascular pathobiology pathways. In 2018, the program will award a one-year grant of up to $100,000 to fund a mentored project.

The MPS DC is expected to be the central clearinghouse for TC data management, and will incorporate novel approaches and technologies for data management, data mining and meta-analyses, and data sharing across many organs and tissues, diseases, data types, and TC platforms. The MPS Data center is expected to provide different levels of public and tiered access to TC information for basic and clinical researchers, academic and practicing physicians, the pharmaceutical industry, NIH, FDA and other government agencies, patients, and the lay public. The MPS Data Center will work with IQ Consortium members to develop and make available a secure, customizable coordinated data management system for collection, storage, and analyses of diverse data types from multiple TC platforms being developed and used for drug screening, safety and efficacy testing.

We encourage innovators to submit potentially ground-breaking ideas in perinatal care, including a particular interest in the following areas:  - Consumer Healthcare  - Community Health Approaches - Health Technologies  - Medical Devices  - Patient Care - Pharmaceuticals - Cross-sector Initiatives   Priority will be given to science-based potential innovations backed by data.  Applications that clearly describe a concept or path forward to achieve these goals will also be considered during evaluation. Please keep in mind that no idea is too big or too early for consideration. The goal of the Maternal Health QuickFire Challenge is to discover solutions aimed to help mothers survive and prevent adverse consequences from pregnancy and childbirth.  These potential solutions should be meet the below outlined criteria. The submitted potential solution must be either be pioneering or evidence based. Please provide data supporting the theory of change or the intervention accordingly. Submitted ideas must meet at least three of the below criteria: - Actionable - is the project achievable? - Measurable in terms of health impact - Filling a current data gap - Proven sustainability or strong rationale for a sustainable business model - Scalable

We encourage innovators to submit potentially ground-breaking ideas in perinatal care, including a particular interest in the following areas:  - Consumer Healthcare  - Community Health Approaches - Health Technologies  - Medical Devices  - Patient Care - Pharmaceuticals - Cross-sector Initiatives   Priority will be given to science-based potential innovations backed by data.  Applications that clearly describe a concept or path forward to achieve these goals will also be considered during evaluation. Please keep in mind that no idea is too big or too early for consideration. The goal of the Maternal Health QuickFire Challenge is to discover solutions aimed to help mothers survive and prevent adverse consequences from pregnancy and childbirth.  These potential solutions should be meet the below outlined criteria. The submitted potential solution must be either be pioneering or evidence based. Please provide data supporting the theory of change or the intervention accordingly. Submitted ideas must meet at least three of the below criteria: - Actionable - is the project achievable? - Measurable in terms of health impact - Filling a current data gap - Proven sustainability or strong rationale for a sustainable business model - Scalable

The purpose of this funding opportunity is to conduct activities to promote and support vaccination services within the pharmacy setting. Activities include, but are not limited to: - Education/Outreach to pharmacists about current pediatric, adolescent, and adult immunization recommendations and proper vaccine administration - Facilitation of communication and exchange of information between pharmacists and providers and public health programs -Quality Improvement efforts -Improved immunization documentation through use of immunization information systems and data sharing -Coordination with public health preparedness and immunization programs to establish formalized agreements for pandemic vaccine program readiness and response By the end of the project, the awardee is expected to disseminate and promote best practices/successes to a national audience of healthcare providers, including both pharmacists and other healthcare providers.