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The Office of Cooperative Threat Reduction (CTR), part of the Department's Bureau of International Security and Nonproliferation (ISN), sponsors foreign assistance activities funded by the Nonproliferation, Anti-terrorism, Demining and Related Programs (NADR) account, and focuses on mitigating proliferation risk in frontline states and regions where the terrorist threat is on the rise, such as South Asia, the Middle East, and North Africa. ISN/CTR administers the Biosecurity Engagement Program (BEP) program as part of the Global Threat Reduction (GTR) portfolio. BEP's mission involves institutionalizing biorisk management best practices, securing life science institutions and dangerous pathogens, decreasing the risk that scientists with dual-use expertise will misuse pathogens, and promoting adoption of and compliance with comprehensive international frameworks that advance U.S. biological nonproliferation objectives, including United Nations Security Council Resolution (UNSCR) 1540, the Biological Weapons Convention (BWC), the World Health Organization's International Health Regulations, and the European Committee for Standardization (CEN) / International Organization for Standardization (ISO) standards. BEP generally funds activities in three priority pillars and has a focus on long-term sustainability.

This funding opportunity announcement (FOA) is designed to support highly integrated research teams of three to six PD/PIs to address ambitious and challenging research questions that are important for the mission of NIGMS and are beyond the scope of an individual or a few investigators. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Project goals should not be achievable with a collection of individual efforts or projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields. Applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies or infrastructure development are not appropriate for this FOA.

A Simons Collaboration in MPS should address a mathematical or theoretical topic of fundamental scientific importance, where a significant new development creates a novel area for exploration or provides a new direction for progress in an established field. The questions addressed by the collaboration may be concrete or conceptual, but there should be little doubt that answering them would constitute a major scientific milestone. The project should have clearly defined initial activities and goals by which their progress and success can be measured. The support from the foundation should be seen as critical for the objectives of the project.

The objectives of this contract are: 1. For the Contractor to provide FDA with the expertise and support to establish infrastructure such as a Coordinating Center or similar organizational structure 2. To provide FDA with data sources including EHR data for millions of patients across a variety of healthcare settings (i.e., inpatient, outpatient, Emergency Department, etc.) that are readily accessible for use in automated reporting. 3. Develop new capabilities for FDA to conduct datamining and automated reporting of adverse event data, mined from records such as EHRs using accepted case definitions, other text information and codes

The purpose of this Funding Opportunity Announcement [FOA] submitted through the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to stimulate the development and validation of novel tools and analytical methods to target, identify and characterize non-neuronal cells in the brain. This FOA complements previous and ongoing cell-census and tool development efforts initiated under BRAIN, RFA-MH-14-215 and RFA-MH-14-216, that have focused almost exclusively on neuronal cells. The cutting-edge tools and methods developed under this opportunity should focus specifically on providing improved points of entry into non-neuronal cell-types (glial and vascular) to enable their inventory and characterization within the CNS and help define how these cells interact among each other and with neuronal cells to impact functional circuitries. Plans for validating the utility of the tool/technology/method and demonstrating its advantage over currently available approaches will be an essential feature of a successful application. Tools that can be used in several species or model organisms rather than in a single species are especially desirable.

Supports activities in conjunction with NSF-wide programs such as Faculty Early Career Development (CAREER), Research Experiences for Undergraduates (REU), and programs aimed at women, minorities, and persons with disabilities. Further information about all of these programs and activities is available in the Crosscutting Investment Strategies section of the NSF Guide to Programs. The program also supports activities that seek to improve the education and training of physics students (both undergraduate and graduate), such as curriculum development or physics education research directed towards upper-level or graduate physics courses, and activities that are not included in specific programs elsewhere within NSF. The program supports research at the interface between physics and other disciplines and extending to emerging areas. Broadening activities related to research at the interface with other fields, possibly not normally associated with physics, also may be considered.

The mobile or wireless solution must have the potential to solve a problem in the areas of access to education, health, access to communication, economic development, and the environment/disaster relief. The project must be at a stage of research where an advanced prototype or field/market test can occur during the award period, and the technology should have the potential for replication and large-scale impact. Applicants also should have a business plan or basic framework for financial sustainability and rollout.

The program supports four main research thrusts that are envisioned to advance the goal of ubiquitous co-robots: scalability, customizability, lowering barriers to entry, and societal impact. Topics addressing scalability include how robots can collaborate effectively with multiple humans or other robots; how robots can perceive, plan, act, and learn in uncertain, real-world environments, especially in a distributed fashion; and how to facilitate large-scale, safe, robust and reliable operation of robots in complex environments. Customizability includes how to enable co-robots to adapt to specific tasks, environments, or people, with minimal modification to hardware and software; how robots can personalize their interactions with people; and how robots can communicate naturally with humans, both verbally and non-verbally. Topics in lowering barriers to entry include development of open-source co-robot hardware and software, as well as widely-accessible testbeds. Topics in societal impact include fundamental research to establish and infuse robotics into educational curricula, advance the robotics workforce through education pathways, and explore the social, economic, ethical, and legal implications of our future with ubiquitous collaborative robots.

This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality.

NSWC Crane is interested in the research and development of advanced microelectronics screening techniques for counterfeit detection. In particular, research using mass spectrometry for forensic analyses of organic and inorganic compounds associated with microelectronic, especially the compounds and materials associated with Plastic-Encapsulated Microelectronics (PEM's).

The purpose of this initiative is to invite SBIR applications to stimulate new and innovative multipurpose prevention technologies (MPTs) through the development of new combinations of agents and delivery systems to prevent HIV infection and unintended pregnancy among adolescent girls and young women. HIV and unintended pregnancy are two major public health problems affecting young women globally. Combination prevention modalities may be more desirable and lead to better adherence in the end user, especially among younger populations. A viable and effective combination prevention modality would be ideal and critical for these young women who are at risk for HIV and who desire protection against pregnancy.

The core technology to be developed in this program is the capability to automatically elicit information from a malicious adversary in order to identify, disrupt, and investigate social engineering attacks. ASED will do this by mediating communications between users and potential attackers with bots that actively detect attacks and coordinate investigations to discover the identity of the attacker.

DARPA is soliciting innovative research proposals in the area of physical design of electronic circuits and systems. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems. The Design thrust of the Electronics Resurgence Initiative (ERI): Page 3 Investments will address today's System-On-Chip (SoC) design complexity and cost barriers, creating the environment needed for the next wave of US semiconductor innovation. Programs within this thrust will develop the algorithms and software required to realize a unified layout generator that will enable fully automated "no human in the loop" physical design of SoCs, system-in-packages (SiPs), and printed circuit boards (PCBs) in 24 hours. In parallel, programs will create the building blocks, validation methodologies, and infrastructure required for a scalable open source hardware ecosystem, bringing best practices in software to hardware design.

The objective of this announcement is to (1) develop baseline FXR system concept(s); (2) estimate and substantiate SWAP-C and effective isotropic radiated power (EIRP) under a flyaway cost constraint; (3) assess current technology and propose new technology development required to achieve capability; (4) assess performance; (5) conduct trade studies; and (6) optionally perform additional trade studies. The results of these activities with industry will help the Government inform potential FXR technology investments and assess risk of draft FXR requirements in particular with respect to the combination of SWAP-C, EIRP and acquisition cost.

The Office of Naval Research (ONR) is interested in receiving proposals for Long-Range Science and Technology (S&T) Projects which offer potential for advancement and improvement of Navy and Marine Corps operations. Readers should note that this is an announcement to declare ONR's broad role in competitive funding of meritorious research across a spectrum of science and engineering disciplines. A brief description of the ONR Program Codes and the science and technology thrusts that ONR is pursuing is provided below. Additional information can be found at the ONR website at http://www.onr.navy.mil/Science- Technology/Departments.aspx.

Background: John C. Stennis Space Center (SSC) is the primary NASA rocket propulsion testing center. SSC tests items ranging from multi-engine stages to individual components of rocket engines. Propulsion test customers include NASA, the Department of Defense and the commercial space launch industry. SSC manages a large federal city that is home to over forty federal, state, university and industry entities. SSC manages a restricted airspace that is available for development, testing and operation of unmanned aerial vehicles. SSC engineering laboratories design and test electronics, sensors, algorithms and mechanical components. Purpose: This CAN supports identification and implementation of cost-sharing partnerships to develop technology to meet a specific NASA need at SSC. Scope: This notice seeks responses from potential partners interested in entering into a Cooperative Agreement with NASA for the joint development of technologies to meet SSC needs.

The Science of Learning program supports potentially transformative basic research to advance the science of learning. The goals of the SL Program are to develop basic theoretical insights and fundamental knowledge about learning principles, processes and constraints. Projects that are integrative and/or interdisciplinary may be especially valuable in moving basic understanding of learning forward but research with a single discipline or methodology is also appropriate if it addresses basic scientific questions in learning. The possibility of developing connections between proposed research and specific scientific, technological, educational, and workforce challenges will be considered as valuable broader impacts, but are not necessarily central to the intellectual merit of proposed research. The program will support research addressing learning in a wide range of domains at one or more levels of analysis including: molecular/cellular mechanisms; brain systems; cognitive affective, and behavioral processes; and social/cultural influences. The program supports a variety of methods including: experiments, field studies, surveys, secondary-data analyses, and modeling.

This Other Transaction Solicitation (OTS) Call (70RSAT18R00000002) - Land Border Biometric Exit Facial Recognition Verification Technologies - is issued against Department of Homeland Security (DHS), Science & Technology (S&T), Silicon Valley Innovation Program (SVIP), 5-Year Innovation Other Transaction Solicitation (OTS), HSHQDC-16-R-B0005 (current issue). The OTS describes the overarching program details whereas the call describes the specific problem set. The implementation of a biometric exit system at U.S. Ports of Entry (POEs) along land borders remains a challenge for several reasons including, but not limited to: environmental conditions, speed of travel, and lack of infrastructure. At land-based POEs, infrastructure is a key inhibitor to track the exit of travelers using biographic or biometric data. In addition, the need for uninhibited vehicle traffic flow at land borders is perhaps the greatest challenge for land-border POEs. To avoid having travelers in vehicles stop at border crossings, which could create significant traffic delays, U.S. Customs and Border Protection (CBP) is working to implement a face biometric entry-exit system in a way that poses the least impact on travel and trade. This call is looking for innovative solutions to capture facial recognition quality photos from travelers in order to facilitate identity checks without requiring occupants to leave the vehicle.

This ROSES NRA (NNH17ZDA001N) solicits basic and applied research in support of NASA's Science Mission Directorate (SMD). The NRA covers all aspects of basic and applied supporting research and technology in space and Earth sciences, including, but not limited to: theory, modeling, and analysis of SMD science data; aircraft, scientific balloon, sounding rocket, International Space Station, CubeSat and suborbital reusable launch vehicle investigations; development of experiment techniques suitable for future SMD space missions; development of concepts for future SMD space missions; development of advanced technologies relevant to SMD missions; development of techniques for and the laboratory analysis of both extraterrestrial samples returned by spacecraft, as well as terrestrial samples that support or otherwise help verify observations from SMD Earth system science missions; determination of atomic and composition parameters needed to analyze space data, as well as returned samples from the Earth or space; Earth surface observations and field campaigns that support SMD science missions; development of integrated Earth system models; development of systems for applying Earth science research data to societal needs; and development of applied information systems applicable to SMD objectives and data.

This ROSES NRA (NNH17ZDA001N) solicits basic and applied research in support of NASA's Science Mission Directorate (SMD). The NRA covers all aspects of basic and applied supporting research and technology in space and Earth sciences, including, but not limited to: theory, modeling, and analysis of SMD science data; aircraft, scientific balloon, sounding rocket, International Space Station, CubeSat and suborbital reusable launch vehicle investigations; development of experiment techniques suitable for future SMD space missions; development of concepts for future SMD space missions; development of advanced technologies relevant to SMD missions; development of techniques for and the laboratory analysis of both extraterrestrial samples returned by spacecraft, as well as terrestrial samples that support or otherwise help verify observations from SMD Earth system science missions; determination of atomic and composition parameters needed to analyze space data, as well as returned samples from the Earth or space; Earth surface observations and field campaigns that support SMD science missions; development of integrated Earth system models; development of systems for applying Earth science research data to societal needs; and development of applied information systems applicable to SMD objectives and data.