The NIH Pioneer Award initiative complements NIH's traditional, investigator-initiated grant programs by supporting individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges that have the potential to produce an unusually high impact on a broad area of biomedical or behavioral research. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigators research program or elsewhere.
The HRP contains six Elements: Space Radiation, Human Health and Countermeasures, Exploration Medical Capability, Behavioral Health and Performance, Space Human Factors and Habitability, and International Space Station Medical Project. Fourteen disciplines or areas support the Program: Behavioral Health and Performance, Bone, Cardiovascular, Extravehicular Activity, Immunology, Medical Capabilities, Muscle, Nutrition, Pharmacology, Radiation, Sensorimotor, Advanced Food Technology, Advanced Environmental Health, and Space Human Factors Engineering. The National Space Biomedical Research Institute (NSBRI) is a non-profit organization competitively selected by NASA that uses an integrated team approach to advance Biomedical research and countermeasure development. NSBRI works in close partnership with the HRP through a Cooperative Agreement. The NRA will cover all aspects of research to provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration, and to ensure safe and productive human spaceflight. Awards generally range from under $100K per year for focused, limited efforts (e.g., data analysis) to $450K per year for extensive activities (e.g., development of scientific hardware). The funds available for awards in each program element offered in the NRA range from less than one to several million dollars, which allow selection from a few to as many as a dozen proposals depending on the program objectives and the submission of proposals of merit. Awards will be made as grants. The period of performance for an award will be one to five years. Any changes or modifications to any of these guidelines will be specified in the descriptions of the relevant program elements in the solicited research response area appendices of this solicitation.
This administrative supplement funding opportunity is part of the Common Fund Metabolomics Program created to increase and improve the nation's ability to undertake metabolomics analyses in translational and clinical research. Metabolomics has great potential to advance our understanding of human diseases, but requires specialized expertise in metabolomics study design, technology, and data analysis and interpretation. This FOA supports supplemental funds to current NIH-funded research projects for new interactive collaborations between basic or clinical researchers and metabolomics experts to add biomedical studies requiring a metabolomics approach. In addition to enhancing the parent grant by adding metabolomics analyses, collaborative projects must include activities to increase the expertise of the biomedical research group in key aspects of metabolomics study design, analysis, and data interpretation.
The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grants (T35) to eligible, domestic institutions to develop and/or enhance research training opportunities for predoctoral students interested in careers in biomedical, behavioral or clinical research. Many NIH Institutes and Centers (ICs) use this NRSA program exclusively to support intensive, short-term research training experiences for health professional students (medical students, dental students, and/or students in other health-professional programs) during the summer. This program is also intended to encourage training of graduate students in the physical or quantitative sciences to pursue research careers by short-term exposure to, and involvement in, the health-related sciences. The training should be of sufficient depth to enable the trainees, upon completion of the program, to have a thorough exposure to the principles underlying the conduct of biomedical research.
The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The Innovative Programs to Enhance Research Training (IPERT) R25 funding opportunity announcement from NIGMS seeks applications that propose creative and innovative educational activities to complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs. The goal of this NIGMS R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs. To this end, this funding opportunity announcement encourages activities with a primary focus on courses for skills development, structured mentoring activities, and outreach programs.
The purpose of this Funding Opportunity Announcement (FOA) is to provide continuing support for the Informatics, Coordination and Service Center (ICSC) unit of the Mutant Mouse Resource and Research Centers (MMRRC) program. The ICSC is expected to provide informatics and coordinating services to the centers of the MMRRC and biomedical researchers. These services include maintenance and further development of a public website portal and Customer Service Center; operation of the order processing system; review and processing of applications from donating investigators; facilitation of interactions with biomedical investigators, informatics services, database activities, and the archive of MMRRC documents and files; coordination of requests to donate mouse strains to the MMRRC and to order mouse strains from the MMRRC; oversight of marketing efforts; and completion of monthly and yearly metrics reports. Moreover, the ICSC will host and actively participate in the monthly teleconference, annual consortium meeting, and compose reports and summaries from these forums.
The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIH R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs and foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on developing courses for skills development, specifically, training modules for graduate students, postdoctoral fellows, and beginning investigators designed to enhance data reproducibility.
This Funding Opportunity Announcement (FOA) announces an opportunity for eligible investigators receiving research funding from The National Institutes of Health (NIH) to request administrative supplement support. The "parent" awards and the proposed administrative supplements must be in areas of cancer, allergy, immunology, and/or infectious diseases (including HIV/AIDS and its co-morbidities). The overall goal of this supplement program is to enhance ongoing research efforts through collaborations with Brazilian scientists in these scientific areas under the new U.S.-Brazil Collaborative Biomedical Research Program.
The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIH R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral and clinical research needs and foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on developing courses for skills development, specifically, training modules for graduate students, postdoctoral fellows, and beginning investigators designed to enhance data reproducibility.
The purpose of this small research grant Funding Opportunity Announcement (FOA) is to foster collaboration between bioinformaticians, metabolomics experts, and/or biomedical researchers in efforts to improve the ability to analyze metabolomics data to address biomedical questions.
The purpose of this small research grant Funding Opportunity Announcement (FOA) is to foster collaboration between bioinformaticians, metabolomics experts, and/or biomedical researchers in efforts to improve the ability to analyze metabolomics data to address biomedical questions.
The goal of a Bioengineering Research Partnership (BRP) is to drive the development and speed the adoption of promising tools and technologies that can address important biomedical problems for which insufficient or no solutions exist. The use of engineering principles is encouraged to establish these tools and technologies as robust, well-characterized solutions that fulfill an unmet need. A synergistic partnership between engineering and the life, physical, and computational sciences is also encouraged, where the unique skills of each discipline combine to enhance our understanding of life science processes or the practice of medicine.
The purpose of this FOA is to encourage BRP applications that: 1) establish a robust engineering solution to a problem in biomedical research or the practice of medicine; 2) develop a strategic alliance of multidisciplinary partners based on a well-defined leadership plan; and 3) realize a specific endpoint within 5-10 years based on a detailed plan with a timeline and quantitative milestones.
The purpose of this funding opportunity announcement (FOA) is to support the innovative biomedical and proof-of-concept research needed to understand how reproductive maturation or injury alters the mucosal environments at HIV susceptible sites. This information is essential to provide the safest and most efficacious biomedical prevention strategies (e.g., topical microbicides and Pre-Exposure Prophylaxis (PrEP), etc.) to those populations at heightened risk of HIV infection.
The National Institute of General Medical Sciences (NIGMS) announces the availability of funds for Administrative Supplements to NIGMS-funded T32 Predoctoral Institutional National Research Service Awards (NRSA). These funds are designed to provide support for the implementation and assessment of innovative, novel curricular and training activities aimed at the development of skills needed to be a competitive biomedical research scientist. The funds are designed to promote the reworking and revitalization of biomedical predoctoral research education and training
The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to lead basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the companion PA-18-372.
The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Funding Opportunity Announcement is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional FOA. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
The goal of the Medical Scientist Training Program (MSTP) is to develop a diverse pool of highly trained physician-scientist leaders available to meet the needs of the Nations biomedical research agenda. Specifically, this funding opportunity announcement (FOA) provides support to eligible domestic institutions to develop and implement effective, evidence-based approaches to integrated dual-degree training leading to the award of both professional medical doctorate degrees and research doctorate degrees (Ph.D. or equivalent). With the dual qualification of rigorous scientific research and clinical practice, graduates will be equipped with the skills to develop research programs that accelerate the translation of research advances to the understanding, detection, treatment and prevention of human disease, and to lead the advancement of biomedical research. Areas of particular importance to NIGMS are the iterative optimization of MSTP training efficacy and efficiency, fostering the persistence of MSTP alumni in research careers, and enhancing the diversity of the physician-scientist workforce. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation.
The goal of the Graduate Research Initiative for Student Enhancement (G-RISE) program is to develop a diverse pool of scientists earning a Ph.D., who have the skills to successfully transition into careers in the biomedical research workforce. This funding opportunity announcement (FOA) provides support to eligible, domestic institutions to develop and implement effective, evidence-based approaches to biomedical training and mentoring that will keep pace with the rapid evolution of the research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation. This program is limited to applications from training programs at research-active institutions (i.e., those with a 3-year average of NIH Research Project Grant funding less than $7.5 million total costs).
The purpose of this Funding Opportunity Announcement (FOA) is to provide support for New Investigators from backgrounds nationally underrepresented in biomedical and behavioral research to conduct small research projects in the scientific mission areas of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The R21 is intended to support small research projects that can be carried out in a short period of time with limited resources and seeks to facilitate the transition to research independence of New Investigators from backgrounds underrepresented in the biomedical and behavioral sciences. The R21 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.
This initiative will support exploratory research leading to the development of innovative technologies for biomedical research. The program will recognize and reward high risk approaches with potential for significant impact. Projects should entail a high degree of risk or novelty, which will be offset by a correspondingly high potential impact. However, the possible impact is likely to be far off. Application of the proposed technology to specific biomedical questions is considered beyond the scope of the program, should not be included, and would not be funded. The goal of this FOA is to support proof of concept studies for feasibility and exploratory technology development. Feasibility must not have already been established in the literature or with preliminary data. Published data can be used to establish the current state of the art but cannot forecast or predict project outcomes. Preliminary data for any purpose might appear to forecast the likelihood of success. Therefore, no unpublished data is allowed. While unpublished data are not permitted, references and data from widely available preprints that have a Digital Object Identifier (DOI) are acceptable.
