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The goal of the CPS program is to develop the core system science needed to engineer complex cyber-physical systems that people can use or interact with and depend upon. Some of these may require high-confidence or provable behaviors. The program aims to foster a research community committed to advancing research and education in CPS and to transitioning CPS science and technology into engineering practice. By abstracting from the particulars of specific systems and application domains, the CPS program seeks to reveal cross-cutting fundamental scientific and engineering principles that underpin the integration of cyber and physical elements across all application sectors.

The Centers of Excellence on Environmental Health Disparities (EHD) research program is a collaborative effort supported by the National Institute on Minority Health and Health Disparities (NIMHD), the National Institute of Environmental Health Sciences (NIEHS), and the U.S. Environmental Protection Agency (EPA) that encourages basic, biological, clinical, epidemiological, behavioral and/or social scientific investigations of disease conditions that are known to be a significant burden in low socioeconomic and health disparate populations. The centers define environmental health disparities as inequities in illnesses that are mediated by disproportionate exposures associated with the social, natural and built environments. The kick-off meeting will feature presentations from each of the five funded centers highlighting their proposed research.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH.  The over-arching goal of this National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce.  NIDDK's Short-Term Research Experience for Underrepresented Persons (STEP-UP) provides funding to research institutions to provide for a national summer research experience program for both high school and undergraduate students for eight to ten weeks.  STEP-UP seeks to facilitate exposure opportunities for students from diverse backgrounds underrepresented in biomedical research on a national basis, including individuals from disadvantaged backgrounds, individuals from underrepresented racial and ethnic groups and individuals with disabilities.

The Cellular and Biochemical Engineering (CBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced biomanufacturing in support of the therapeutic cells, biochemical, biopharmaceutical and biotechnology industries.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the CBE program.  Fundamental to many research projects in this area is the understanding of how biomolecules, cells and cell populations interact in the biomanufacturing environment, and how those molecular-level interactions lead to changes in structure, function, and behavior.  The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches, and proposals that address emerging research areas and technologies that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities.

The "epitranscriptome" refers to chemical modifications of RNA molecules.  RNA modifications in the brain have been reported to regulate the fate and function of both coding and noncoding RNAs and are emerging as a critical element of cellular function. The purpose of this initiative is to stimulate research into the functions of modified RNAs in the brain and in the associated modification proteins that act on RNA (readers, writers, and erasers) that play a role in basic neurobiological and behavioral processes implicated in mental and substance use disorders.   

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The goal of this funding opportunity announcement (FOA) is to complement and/or enhance the training of a workforce to meet the nation's biomedical, behavioral, and clinical research needs in utilizing'Big Data.'

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The goal of this Big Data to Knowledge (BD2K) Program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs in Big Data Science.

The Division of Integrative Organismal Systems (IOS) supports research aimed at understanding why organisms are structured the way they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators (PIs) are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties. Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, and function, physiological processes, functional morphology, symbioses, interactions of organisms with biotic and abiotic environments, and animal behavior. Proposals are welcomed in all areas of science supported by the Division of Integrative Organismal Systems. All investigator-initiated proposals to the core programs in the Division of Integrative Organismal Systems must now be invited based on merit review of preliminary proposals. 

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three, four, or five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs utilize the K01 award to increase research workforce diversity by providing enhanced research career development opportunities.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The goal of this NIGMS R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce. To this end, this funding opportunity announcement encourages the development of creative educational activities with a primary focuses on research experiences, courses for skills development and mentoring activities.

The Ecology and Evolution of Infectious Diseases program supports research on the ecological, evolutionary, and socio-ecological principles and processes that influence the transmission dynamics of infectious diseases. The central theme of submitted projects must be quantitative or computational understanding of pathogen transmission dynamics. The intent is discovery of principles of infectious disease transmission and testing mathematical or computational models that elucidate infectious disease systems. Projects should be broad, interdisciplinary efforts that go beyond the scope of typical studies. They should focus on the determinants and interactions of transmission among humans, non-human animals, and/or plants. This includes, for example, the spread of pathogens; the influence of environmental factors such as climate; the population dynamics and genetics of reservoir species or hosts; or the cultural, social, behavioral, and economic dimensions of disease transmission. Research may be on zoonotic, environmentally-borne, vector-borne, or enteric diseases of either terrestrial or freshwater systems and organisms, including diseases of animals and plants, at any scale from specific pathogens to inclusive environmental systems. Proposals for research on disease systems of public health concern to developing countries are strongly encouraged, as are disease systems of concern in agricultural systems. Investigators are encouraged to involve the public health research community, including for example, epidemiologists, physicians, veterinarians, food scientists, social scientists, entomologists, pathologists, virologists, or parasitologists with the goal of integrating knowledge across disciplines to enhance our ability to predict and control infectious diseases.

This award program is designed to enhance our existing support of autism research by providing timely resources to enable focused experiments highly relevant to our mission. A deeper understanding of the mechanisms underlying autism spectrum disorders or potential therapeutic approaches will require investigation at multiple levels, including but not limited to studies focused on gene discovery, molecular mechanisms, circuits, anatomy, and cognition and behavior. We will consider proposals at all of these levels. The maximum budget is $60,000, including indirect costs for one (1) year, non-renewable. Explorer Awards are intended to provide resources to support exploratory experiments that will strengthen hypotheses and lead to the formulation of competitive applications for subsequent larger-scale funding by SFARI or other organizations. Innovative, high-risk/high-impact proposals are encouraged. We especially encourage applications from investigators who are new to the field of autism, but who have expertise that could be brought to bear on this complex disorder.

Due to the ubiquitous presence of catalysis in the many aspects of goods and services impacting our lives, the Catalysis and Biocatalysis program has many potential directions for funding support.  Programs in this area encompass a blend of fundamental and innovative applied research drivers.  All programs are hypothesis-driven, and the experimental programs aimed at resolving the issues frequently combine a variety of approaches.  Chemical engineering and chemistry are intertwined.  Proposals which receive funding in this Program may include any number of the following broad scopes: Catalyst Synthesis, Characterization, Behavior and Performance Kinetics and Mechanisms of Key Catalytic Reactions Catalysis at Surfaces or in Reactor Process Streams Synthesis and Fabrication of Component Materials and Catalyst Composites Modeling and Fundamental Studies of a Catalyst or Catalytic Process Catalysts and Studies for Renewable Energy Systems. These approaches apply equally to classical inorganic or carbon catalysts as well as to enzymatic or biocatalysts.  Specialized materials synthesis procedures may be necessary to provide active catalysts in any of the studies.  Applications-driven studies, such as Biomass conversion catalysis, Electrocatalysis and Photocatalysis, involving energy interconversion devices or systems employing catalysts are highly desired.

The Biotechnology, Biochemical, and Biomass Engineering (BBBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes (in vivo, in vitro, and/or ex vivo) and eventually leads to the development of enabling technology and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  Quantitative assessments of bioprocesses are considered vital to successful research projects in the BBBE program.  Fundamental to many research projects in this area is the understanding of how biomolecules and cells interact in their environment, and how those molecular level interactions lead to changes in structure, function, phenotype, and/or behavior.  The program encourages proposals that address emerging research areas and technologies that effectively integrate knowledge and practices from different disciplines, and effectively incorporate ongoing research into educational activities. Research projects of particular interest in BBBE include, but are not limited to: Metabolic engineering and synthetic biology Quantitative systems biotechnology Tissue engineering and stem cell culture technologies Protein engineering/protein design Development of novel "omics" tools for biotechnology applications

The purpose of the Academic Research Enhancement Award (AREA) program is to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. AREA grants create opportunities for scientists and institutions, otherwise unlikely to participate extensively in NIH research programs, to contribute to the Nation's biomedical and behavioral research effort. AREA grants are intended to support small-scale research projects proposed by faculty members of eligible, domestic institutions, to expose students to meritorious research projects, and to strengthen the research environment of the applicant institution.

DARPA seeks new methods for analysis and decoding of neural signals in order to understand how neural stimulation could be applied to facilitate recovery of memory encoding following brain injury. Ultimately, it is desired to develop a prototype implantable neural device that enables recovery of memory in a human clinical population. Additionally, the program encompasses the development of quantitative models of complex, hierarchical memories and exploration of neurobiological and behavioral distinctions between memory function using the implantable device versus natural learning and training.

Objective To encourage and adequately fund the most innovative and meritorious research projects from independent investigators. Science Focus Research broadly related to cardiovascular function and disease and stroke, or to related clinical, basic science, bioengineering or biotechnology, and public health problems, including multidisciplinary efforts. Disciplines Proposals are encouraged from all basic disciplines as well as epidemiological, behavioral, community and clinical investigations that bear on cardiovascular and stroke problems.

PoLS encourages research that emphasizes the physical principles of organization and function of living systems, including the exploration of artificial life forms. While the problems under study must be important to advancing our understanding of the living world in a quantitative way, particular emphasis will be placed on those projects in which lessons learned from the biological application also expand the intellectual range of physics. Awards will cover a broad spectrum of physics approaches in biology, ranging from the physical principles and mechanisms at the single cell level such as cellular organization (e.g. cytoskeleton), energy metabolism, gene regulation and intracellular and intercellular communication, to collective behavior and evolution of complexity in life forms and living populations of organisms. This systems approach in physics has been very successful in understanding inanimate systems, and has the potential to bring deep understanding of the world of animated, replicating systems, through testable phenomenological theories. The program funds individual investigators, although collaborative proposals between physicists and biological researchers are welcome. Proposals with potential societal impact such as renewable energy and human health are good examples of strong broader impact and are of interest to the program.

Prevent Blindness Ohio is accepting applications for its 2014 Young Investigator Student Fellowship Awards for Female Scholars in Vision Research. The Fellowship Program is designed to provide support for outstanding female scientists committed to pursuing biomedical, behavioral or clinical research careers relevant to the mission of Prevent Blindness Ohio - to prevent blindness and preserve sight. 

The Ecology and Evolution of Infectious Diseases program supports research on the ecological, evolutionary, and socio-ecological principles and processes that influence the transmission dynamics of infectious diseases. The central theme of submitted projects must be quantitative or computational understanding of pathogen transmission dynamics. The intent is discovery of principles of infectious disease transmission and testing mathematical or computational models that elucidate infectious disease systems. Projects should be broad, interdisciplinary efforts that go beyond the scope of typical studies. They should focus on the determinants and interactions of transmission among humans, non-human animals, and/or plants. This includes, for example, the spread of pathogens; the influence of environmental factors such as climate; the population dynamics and genetics of reservoir species or hosts; or the cultural, social, behavioral, and economic dimensions of disease transmission. Research may be on zoonotic, environmentally-borne, vector-borne, or enteric diseases of either terrestrial or freshwater systems and organisms, including diseases of animals and plants, at any scale from specific pathogens to inclusive environmental systems. Proposals for research on disease systems of public health concern to developing countries are strongly encouraged, as are disease systems of concern in agricultural systems. Investigators are encouraged to involve the public health research community, including for example, epidemiologists, physicians, veterinarians, food scientists, social scientists, entomologists, pathologists, virologists, or parasitologists with the goal of integrating knowledge across disciplines to enhance our ability to predict and control infectious diseases.