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This FOA is intended to encourage exploratory studies to : (1) increase our understanding of how music affects the brain, body, and behavior and (2) use that knowledge to develop evidence-based music interventions to enhance health or treat specific diseases and disorders.  Proposed R21 projects can investigate how music is processed by or modifies the brain, or how it affects specific biological functions during childhood development and learning, adulthood, and aging.  Projects can also include preliminary interventions that provide a basis for therapeutic interventions. When appropriate, collaborations among basic researchers, technology developers, music intervention experts, or other clinical researchers are highly encouraged.

This broad spectrum FOA is intended to: (1) increase our understanding of how music affects the brain, body, and behavior and (2) use that knowledge to develop evidence-based music interventions to enhance health or treat specific diseases and disorders.  Proposed R01 projects can investigate how music is processed by or modifies the brain, or how it affects specific biological functions during childhood development and learning, adulthood, and aging.  Projects can also include preliminary interventions that provide a basis for therapeutic interventions. When appropriate, collaborations among basic researchers, technology developers, music intervention experts, or other clinical researchers are highly encouraged.

The Cognitive Neuroscience program seeks highly innovative proposals aimed at advancing a rigorous understanding of human cognition, including how the human brain mediates action, affect, creativity, decision making, intentionality, perception, social processes, and thought.  Topics may bear on core functions such as attention, emotion, empathy, executive processes, language, learning, memory, music, sensory processing, sleep, representation of self and other, reasoning and rhythm. Topics may also include how human cognition develops and changes in the brain across the lifespan. The program is particularly interested in supporting the development of new techniques and technologies for recording, analyzing, and modeling complex brain activity and human brain mapping. Such projects should include a plan for sharing new software and other technologies with the research community at large.  Additionally, the program is interested in supporting projects addressing the growing amount of data collected across disparate lab environments, which may require new standardization, curation, and sharing solutions.  Studies of disease states (e.g., Alzheimer's disease, Autism, brain damaged patients, Parkinson's disease and Schizophrenia) may be components of projects supported by this program. However, the emphasis in such projects must be to advance basic scientific understanding of healthy neural mechanisms, and not on disease etiology, diagnosis, or treatment.

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