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MiamiOH OARS

Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional) - 0 views

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    This Funding Opportunity Announcement (FOA) solicits applications for research projects that will apply computational approaches to develop parametrically detailed behavioral assays across mental-health relevant domains of function. These projects should focus on behavior in humans and test computational models in healthy subjects. NIMH is particularly interested in the study of behavioral measures, models, and parameters that have the potential for back-translation from humans to animals, especially for pre-clinical therapeutics development, and/or in models that have the potential to be extended to clinical populations.  
MiamiOH OARS

Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute... - 0 views

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    Recent advances in endovascular thrombectomy offer a new opportunity to reconsider neuroprotective agents as adjunctive therapies to extend the time window for reperfusion and to improve long-term functional outcome. The purpose of this funding opportunity announcement (FOA) issued by NINDS is to invite applications for the Coordinating Center (CC) for the NIH Stroke Preclinical Assessment Network (SPAN). SPAN will facilitate testing of up to 6 promising neuroprotective drugs or interventions to be given prior to or at the time of reperfusion in experimental models of ischemic stroke (e.g., transient middle cerebral artery occlusion). The CC will work with the awarded network sites (RFA-NS-18-033) and will provide centralized administrative oversight and coordination of all aspects of the network. If successful, this network will accelerate the identification of the most promising neuroprotective therapies for future pivotal clinical trials and span the gap between preclinical and clinical testing, in a cost-and time-effective fashion.
MiamiOH OARS

Fellowship Announcement | The Matsumae International Foundation - 0 views

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    Eligibility Requirements:
    Applicants of non-Japanese nationality; a Doctorate degree; must be 49 years old or under;  not have been in Japan previously; have firm positions and professions in their home nations; etc.

    Host Institution In Japan:
    Applicants are free to select host institutions (university research laboratories, national research institutions or the corresponding facilities of private industry)

    Fellowship Details:
    Stipend for research and stay, Insurance, Air transportation (a round-trip air ticket to/from Tokyo) and Lump sum on arrival

    Period & Number of Fellowships:
    For a period of from three to six months; the number of fellowships is about 20 persons each year.
MiamiOH OARS

BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specifi... - 0 views

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    The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative funding opportunity announcement is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits in large brains. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and circuit specific tools will require extensive focused research designed to remove barriers to delivery of gene therapies. In addition to identification and removal of barriers, the need to specifically target dysfunctional circuitry poses additional challenges. Neuroscience has experienced an impressive influx of exciting new research tools in the past decade, especially since the launch of the BRAIN Initiative. However, the majority of these cutting-edge tools have been developed for use in model organisms, primarily rodents, fish and flies. These cutting-edge tools, such as viral delivery of genetic constructs, are increasingly adaptable to larger mammalian brains and more importantly are emerging as potential human therapeutic strategies for brain disorders. A pressing need to develop tools for use in large brains or those that are more directly relevant to the human brain is the focus of this initiative. The initiative will support initial proof of principle studies aimed at demonstrating the feasibility of this approach in humans and other mammalian species (non-human primate [NHP]/sheep/pigs).
MiamiOH OARS

Limited Competition: Additional Sequencing for the Alzheimer's Disease Sequencing Proje... - 0 views

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    The National Institute on Aging invites revision applications to ongoing NIA-supported Cooperative Agreements in the area of the genetics of Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD). This Funding Opportunity Announcement (FOA) invites applications specific to sample acquisition, genome wide association studies, whole genome sequencing, quality control checking, variant calling, and data calling that will support the generation of data for the Alzheimer's Disease Sequencing Project Follow-Up Study.
MiamiOH OARS

BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specifi... - 0 views

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    The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits and provide insights into cellular interactions that underlie brain function. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and circuit specific tools will require extensive focused research designed to remove barriers to delivery of gene therapies. In addition to identification and removal of barriers, the need to specifically target dysfunctional circuitry poses additional challenges. Neuroscience has experienced an impressive influx of exciting new research tools in the past decade, especially since the launch of the BRAIN Initiative.
MiamiOH OARS

Alzheimer Centers for Discovery of New Medicines (U54 Clinical Trial Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) invites U54 Cooperative Agreement applications aiming to establish multi-component Alzheimer Centers for the Discovery of New Medicines. The overarching purpose of this Centers program is to improve, diversify and reinvigorate the Alzheimers disease (AD) drug development pipeline by accelerating the characterization and experimental validation of next generation therapeutic targets and, integrating the targets into drug discovery campaigns. In addition, this program aims to de-risk potential therapeutics to the point that industry will invest in them, accelerating the delivery of new drugs to AD patients. To this end, the funded Centers will design, develop and disseminate tools that support target enabling packages (TEPs) for the experimental validation of novel, next generation therapeutic targets, including those emanating from the NIA-funded, target discovery programs such as AMP-AD and, initiate early stage drug discovery campaigns against the enabled targets.
MiamiOH OARS

Naval Medical Research Center: Research and Development of Operational and Undersea Med... - 0 views

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    The intent of this award is to fund an organization that can provide collaborative research assistance under three research focus areas:1) undersea medicine research, 2) regenerative medicine research and 3) neurotrauma research. The award will be issued as a cooperative agreement between the recipient and the Government (OUMD-NMRC (Operational and Undersea Medicine Directorate at Naval Medical Research Center)). The award recipient (awardee) will collaborate with OUMD-NMRC to develop and implement scientific research efforts and share substantial programmatic involvement with OUMD-NMRC.
MiamiOH OARS

Early Stage Clinical Trials for the Spectrum of Alzheimers Disease and Age-related Cogn... - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications that propose to develop and implement early stage (Phase I or II) clinical trials of promising pharmacological and non-pharmacological interventions in individuals with age-related cognitive decline and in individuals with Alzheimer's disease (AD) across the spectrum from pre-symptomatic to more severe stages of disease, as well as to stimulate studies to enhance trial design and methods.
MiamiOH OARS

RFA-MH-19-146: BRAIN Initiative: Standards to Define Experiments Related to the BRAIN I... - 0 views

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    This Funding Opportunity Announcement (FOA) solicits applications to develop standards that describe experimental protocols that are being conducted as part of the BRAIN Initiative. It is expected that applications will solicit community input at all stages of the process.  It is recommended that the first step of standard development will involve sharing data between different key groups in the experimental community in order to ensure that the developing standard will cover the way that all of those groups are collecting data. The developed standard is expected to be made widely available.
MiamiOH OARS

RFA-MH-19-147: BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R01... - 0 views

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    The BRAIN Initiative: The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative® is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, will show how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat and prevent brain disorders.
MiamiOH OARS

BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R01 Clinical Trial... - 0 views

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    This Funding Opportunity Announcement (FOA) solicits applications to develop informatics tools for analyzing, visualizing, and integrating data related to the BRAIN Initiative or to enhance our understanding of the brain.
MiamiOH OARS

RFA-AG-19-009: NIA AD/ADRD Health Care Systems Research Collaboratory (U54 - Clinical T... - 0 views

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    The purpose of this FOA is to solicit applications for the AD/ADRD Health Care Systems Research Collaboratory ("Collaboratory", henceforth) to improve care for persons with dementia (PWD) and their caregivers through health systems. Health and long-term systems for this FOA are defined broadly and include organizations providing care across settings to include primary and specialty outpatient care, acute inpatient care, skilled nursing and other rehabilitation facilities, residential long-term care, and home and community-based services. Organizations may be traditional health care systems (e.g., health maintenance organizations, or HMOs), health insurance companies, managed care plans, home health care providers, memory clinics, nursing homes, assisted living facilities, outpatient clinics, federally-designated health centers, hospitals, and other providers of acute and long-term care.
MiamiOH OARS

High-Priority Behavioral and Social Research Networks in Alzheimer's Disease and Alzhei... - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications to provide infrastructure support to provide infrastructure support for advancing development of specific high priority areas of behavioral and social research of relevance to Alzheimers disease and Alzheimers disease related dementias (AD/ADRD). The infrastructure support will facilitate research networks through meetings, conferences, small scale pilots, short term educational opportunities (such as intensive workshops, summer institutes, or visiting scholar programs), and dissemination to encourage growth and development of specified priority areas and build resources for advancing aging-relevant research in the field at large. Network applications are limited to the following areas: (1) AD/ADRD care and services research and (2) the coordination of international studies conducting the Harmonized Cognitive Assessment Protocol.
MiamiOH OARS

Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Tr... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages exploratory/developmental research grant applications, proposing the development of innovative, collaborative research projects on brain and other nervous system function and disorders throughout life, relevant to low- and middle-income countries (LMICs). Research on neurological, mental, behavioral, alcohol and substance use disorders may span the full range of science from basic to implementation research. Scientists in the United States (U.S.) or upper-middle income countries (UMICs) are eligible to partner with scientists in LMIC institutions. Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories used are as defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups. These grants are expected to foster the development of more comprehensive research programs that contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, prevention, treatment and implementation strategies. The proposed work may also contribute to developing a base for research networking and evidence-based policy beyond the specific research project.
MiamiOH OARS

DoD Parkinson's, Early Investigator Research Award - 0 views

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    The PRP EIRA supports Parkinson's disease-focused research opportunities for individuals in the early stages of their careers, under the guidance of a designated Mentor. The Early Investigator is considered the Principal Investigator (PI) of the application and must exhibit strong potential for, and commitment to, pursuing a career as an investigator at the forefront of Parkinson's disease research; however, the PI is not required to have previous Parkinson's disease research experience. Applications must include at least one Mentor, appropriate to the proposed research project, who has experience in Parkinson's disease research and mentoring as demonstrated by a record of active funding, recent publications, and successful mentorship. The selected Mentor(s) should also demonstrate a clear commitment to the development of the PI toward independence as a Parkinson's disease researcher.
MiamiOH OARS

DoD Parkinson's, Investigator-Initiated Research Award - 0 views

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    The PRP IIRA supports highly rigorous, multidisciplinary, high-impact research projects that have the potential to make an important contribution to Parkinson's disease research and/or patient care. This award mechanism supports the full spectrum of research from basic science through clinical research that specifically focuses on scientific and clinical Parkinson's disease issues, which, if successfully addressed, have the potential to make a major impact in understanding, preventing, diagnosing, or treating Parkinson's disease or enhancing the well-being of individuals experiencing the impact of the disease.
MiamiOH OARS

PAR-18-836: Global Brain and Nervous System Disorders Research Across the Lifespan (R21... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages exploratory/developmental research grant applications, proposing the development of innovative, collaborative research projects on brain and other nervous system function and disorders throughout life, relevant to low- and middle-income countries (LMICs). Research on neurological, mental, behavioral, alcohol and substance use disorders may span the full range of science from basic to implementation research. Scientists in the United States (U.S.) or upper-middle income countries (UMICs) are eligible to partner with scientists in LMIC institutions. Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories used are as defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups.
MiamiOH OARS

Alzheimer's Drug Discovery Foundation Issues RFP for Biomarker Studies | RFPs | PND - 0 views

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    Grants of up to $300,000 over two years will be awarded in support of projects focused on the development of biomarkers previously identified in samples from well-characterized human subjects. Validated methods should be used in quantifying and qualifying biomarkers, with less enthusiasm for the development of novel technologies. Priority biomarker areas include companion biomarkers, neuroimaging, CSF and blood-based biomarkers, and functional activity measures.

MiamiOH OARS

RFA-AG-19-016: High-Priority Behavioral and Social Research Networks in Alzheimer's Dis... - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications to provide infrastructure support for advancing development of specific high-priority areas of behavioral and social research of relevance to Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD). The infrastructure support will facilitate research networks through meetings, conferences, small-scale pilots, short-term educational opportunities (such as intensive workshops, summer institutes, or visiting scholar programs), and dissemination to encourage growth and development of specified priority areas and build resources for advancing aging-relevant research in the field at large. Network applications are limited to the following areas: (1) AD/ADRD care and services research, and (2) the coordination of international studies conducting the Harmonized Cognitive Assessment Protocol.

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