25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort.
Hyppönen E, Boucher BJ, Berry DJ, Power C.
Diabetes. 2008 Feb;57(2):298-305. Epub 2007 Nov 14.
PMID: 18003755
doi: 10.2337/db07-1122
CONCLUSIONS-Serum 25(OH)D is inversely associated with metabolic syndrome, whereas the inverse association with IGF-1 was found only among those without hypovitaminosis D. These results suggest that metabolic syndrome prevalence is the lowest when both 25(OH)D and IGF-1 are high.
An ecologic study of dietary and solar ultraviolet-B links to breast carcinoma mortality rates.
Grant WB.
Cancer. 2002 Jan 1;94(1):272-81.
PMID: 11815987
CONCLUSIONS
It is hypothesized that animal products are associated with risk for breast carcinoma because they are associated with greater amounts of insulin-like growth factor-1and lifetime doses of estrogen. Vegetable products contain several risk reduction components including antioxidants and phytoestrogens. The association with latitude is very likely because of solar UV-B radiation and vitamin D. Alcohol modulates estrogen's effects on breasts. Fish intake is associated with risk reduction through vitamin D and n-3 oils. These results are consistent with those of many case-control and cohort studies but should be assessed in well designed cohort studies.