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"Berberine is a bitter-tasting, yellow, plant alkaloid with a long history of medicinal use in Chinese and Ayurvedic medicine. Berberine is present in the roots, rhizomes and stem bark of various plants including Hydrastis canadensis (goldenseal), Coptis chinensis (coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (tree turmeric). Berberine has also been used historically as a dye, due to its yellow color. Clinical trials have been conducted using berberine. There is some evidence to support its use in the treatment of trachomas (eye infections), bacterial diarrhea, and leishmaniasis (parasitic disease). Berberine has also shown antimicrobial activity against bacteria, viruses, fungi, protozoans, helminths (worms), and chlamydia (STD). Future clinical research is warranted in these areas, as well as cardiovascular disease, skin disorders, and liver disorders.

Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y. J Ethnopharmacol. 2009 Oct 29;126(1):5-17. Epub 2009 Aug 15. PMID: 19686830 doi:10.1016/j.jep.2009.08.009 Conclusions The modern evidences of treating cancer with Huanglian and berberine have a strong linkage with traditional concept and rules of using Huanglian in CM practice. As anticancer candidates with low toxicity, berberine and its altered structure, as well as Huanglian and its formulae, will attract scientists to pursue the potential anticancer effects and the mechanisms by using technologies of genomics, proteomics and other advanced approaches. On the other hand, relatively few in vivo studies have been conducted on anticancer effects of Huanglian and berberine. The clinical application of berberine or Huanglian as novel cancer therapeutic agents requires in vivo validations and further investigations of their anticancer mechanisms.

Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mantena SK, Sharma SD, Katiyar SK. Mol Cancer Ther. 2006 Feb;5(2):296-308. PMID: 16505103 doi: 10.1158/1535-7163.MCT-05-0448 The effectiveness of berberine in checking the growth of androgen-insensitive, as well as androgen-sensitive, prostate cancer cells without affecting the growth of normal prostate epithelial cells indicates that it may be a promising candidate for prostate cancer therapy. The evaluation of ancient herbal medicines may indicate novel strategies for the treatment of prostate cancer, which remains the leading cause of cancer-related deaths in American men (1). In our present investigation, we show that a naturally occurring isoquinoline alkaloid, berberine, significantly inhibits the proliferation and reduces the viability of DU145 and PC-3 as well as LNCaP cells (Fig. 1), which suggests that berberine may be an effective chemotherapeutic agent against both androgen-sensitive and androgen-insensitive prostate cancer cells. Importantly, we found that berberine did not exhibit toxicity to nonneoplastic human prostate epithelial cells under the conditions used, except for a moderate reduction in cell viability at higher concentrations when cells were treated in vitro for an extended period of time. In conclusion, the results of the present study indicate that berberine inhibits proliferation and induces G1-phase arrest and apoptosis in human prostate cancer cells but not in normal human prostate epithelial cells. In addition, we provide mechanistic evidence that berberine-induced apoptosis in prostate carcinoma cells, particularly hormone-refractory prostate carcinoma cells, is mediated through enhanced expression of Bax, disruption of the mitochondrial membrane potential, and activation of caspase-3.

This boswellia from Aggripure provides natural joint care. It increases blood flow to the joints making joints more flexible to rotate and move. The boswellia is also known for its anti inflammatory properties since ancient times. It helps ease the pain and swelling whether in joints or muscles without any side effects. It is recommeded to take 2 capsules daily to improve joint health.

The new law also erases from Qanun e Shahadat the facility relating to questioning the character of ...

The process of sprouting makes the parent seed much more nutrient enriched compared to its non-sprouted counterpart and converts the stored reserves of the seed into simpler forms thus, making them easy to digest, increasing the nutrient content by several folds and also deactivating anti-nutrients

Our organic turmeric toner has a savory, earthy linger. It works as a dark spot remover, giving all skin types a beautiful, luminous complexion. Additionally, it helps with mild skin irritants. Its potent anti-inflammatory and antioxidant properties aid in wound healing while reducing skin irritation. It has a significant amount of antimicrobial ingredients that work to lessen acne and scarring while slowing down free radical damage to skin cells. Use it as a facial toner or activating water in your face masks.

About 540 million people worldwide are affected by back pain at any time. It is predicted that 4 in 10 office workers will undergo lower back pain inflammation. Current non-surgical treatments for back pain conditions are neither effective nor safe. As a non-toxic natural product, curcumin in turmeric has a premium anti-inflammatory profile that reduces back pain and inflammation. Radicular back pain is one of the common causes of lower back pain. Researchers observed that curcumin alleviates radiculopathy.

The leading cause of hypothyroidism is an autoimmune condition called Hashimoto's thyroiditis. Symptoms include fatigue, feeling cold all the time, constipation, weight gain, and more. Curcumin is a compound found in spice turmeric that has antioxidant and anti-inflammatory properties. Some studies have shown that curcumin may help lower TSH levels (a marker for hypothyroidism). Taking curcumin over the long term may help lower TSH levels as well as cholesterol levels.

Researchers are curious about curcumin to create an effective anti-infection therapeutic effect and control fungal infections in cancer patients. Curcumin could grow the fungal infection sustainability among cancer patients with candida. Thus, turmeric curcumin supplements offer a reasonably 'secure cure' against candida with minimal or no adverse effects, even when using a higher curcumin dose.

This neurological condition can leave you in bed for days! Researchers have discovered that curcumin for migraines is an alternative natural remedy that instantly reduces inflammation in the brain by protecting cells from free radicle damage. Neurogenic inflammation has a crucial role in migraine, and curcumin is a renowned herbal compound that has anti-inflammatory effects against suppressing this neuro-inflammation.