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Tero Toivanen

Eide Neurolearning Blog: Why Boys Need Alternatives with Reading and Writing - 0 views

  • If you give girls and boys language tasks, most girls will process the information in the same way (in a specialized language area)
  • help them with word storage and retrieval
  • But for boys, sensitivity to the modality of how words are presented means that an extra steps need to be taken to match words that are picked up by listening and words that are read on the printed page. No wonder dyslexia is much more common in boys - the separate system means that the sight and sound of words are learned as distinct processes.
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  • As a result, verbal competence may be strong in one domain (oral speech for instance), but be weak in another (reading).
  • because boys require two areas and a matching of visual-auditory inputs, impairment in one system may cause the whole language coordination process to fail.
  • The visual-auditory gap may also be why some boys may need to read word-for-word outloud or to themselves (i.e. not silently read) in order to fully comprehend or remember the story.
  • Some careful consideration needs to made of instructional implications for boys given some of these new discoveries. Learning by listening and learning by reading are not synonymous; route-congruent factors(listening - oral presentation, reading - written response) may need to be considered when a learning gap or frank underachievement is seen, and an insistence on the availability of auditory-visual supports (reading along with books-on-tape, detailed handouts for lecture courses) should be a requirement of every classroom.
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    Boys require two areas and a matching of visual-auditory inputs, impairment in one system may cause the whole language coordination process to fail.
David McGavock

The Top 10 Challenges for Brain Science in 2013 - Forbes - 0 views

  • 1. Figure out what fMRI can truly tell us about our brains. 
  • There’s little question fMRI is valuable, but too many disparate forces are out there spinning brain scans in too many ways. Perhaps one solution, or start of a solution, is a summit hosted by a credible, well-respected institute or organization to gather the best of the best minds in the field to establish a game plan moving forward.
  • 2. Determine what role, if any, neuroscience should play in the courtroom.
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  • . Continue crafting a constructive consilience between disciplines.
  • Neuroscience, behavioral science, evolutionary biology, economics, engineering, and even the humanities have all come to the proverbial table in the last few years
  • Produce more applicable knowledge and less curious meanderings.
  • 7. Join forces with more public health sources to engender broader awareness of critical issues. 
  • Try to fight the urge to spin off more headline pablum like “Brain Porn.”
  • How about we spend more time trying to solve the problems and less time concocting clever catch phrases?
  • Shine the light on how far the forces of marketing have exploited brain science advances (this is a genuine public service).
  • I am an unwavering advocate of making sure people understand how the forces of marketing are using the field to sell more products.
  • Again, what is truly “solid applicable knowledge” is frequently debatable (see #1 above), but every year the field–and by that I mean the interdisciplinary field (#3)–has more to offer the public.
  • 8. Put the brakes on “building a brain” — we already have plenty of them.
  • in my opinion we have enough to do with respect to figuring our how our organic brain works without spending massive resources on trying to recreate one.
  • 9. Turn the corner from “what’s wrong with our brains” to “what we can really do about it.” 
David McGavock

What is intelligence ? | BrainFacts.org Blog - 0 views

  • What do we mean when we say someone is intelligent and is there any scientific basis for defining intelligence? These questions have been at the center of a more than century-old debate in psychology.
  • Although it may be practical for people to think of intelligence as something that exists, whether science should consider intelligence and how it would define it remains very controversial.
  • A recent study published by Hampshire et al.1 from the University of Western Ontario has looked into the brain areas that are activated by tasks that are typically used to test for intelligence. In doing so they hoped to determine if brain areas related to cognitive demands are activated altogether as demands increase during intelligence tests of various kinds, or if some areas were activated during tests for a specific intelligence domain and not for others.
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  • The study is interesting because it provides three candidate intelligence factors (instead of 1) that have been built not from intuition about what tasks do but based on the set of brain areas that might contribute to those tasks. However don’t get too excited, the methods used have severe limitations and we are still only at the hypothesis level. We do not know how these areas contribute to performance in intelligence tests and we do not know why they are activated and how they interact together to create the behavior.
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    A recent study published by Hampshire et al.1 from the University of Western Ontario has looked into the brain areas that are activated by tasks that are typically used to test for intelligence. In doing so they hoped to determine if brain areas related to cognitive demands are activated altogether as demands increase during intelligence tests of various kinds, or if some areas were activated during tests for a specific intelligence domain and not for others.
Tero Toivanen

Selective aphasia in a brain damaged bilingual patient : Neurophilosophy - 0 views

  • A unique case study published in the open access journal Behavioral and Brain Functions sheds some light on this matter. The study, by Raphiq Ibrahim, a neurologist at the University of Haifa, describes a bilingual Arabic-Hebrew speaker who incurred brain damage following a viral infection. Consequently, the patient experienced severe deficits in Hebrew but not in Arabic. The findings support the view that specific components of a first and second language are represented by different substrates in the brain.
  • A native Arabic speaker, he learned Hebrew at an early age (4th grade) and later used it competently both professionally and academically.
  • A CT scan showed that he had suffered a massive hemorrhage in the left temporal lobe, which was compressing the tissue on both sides of the central sulcus, the prominent gfissure which separates the frontal and parietal lobes.
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  • A craniotomy was performed to relieve the pressure, and afterwards another scan showed moderate hemorrhage and herpes encephalitis in the left temporal lobe, and another hemorrhage beneath the outer membrane (the dura) lying over the right frontal lobe.
  • During his 2 month stay there, he developed epileptic seizures which originated in the left temporal lobe, and amnestic aphasia (an inability to name objects or to recognize their written or spoken names). 
  • After the rehabilitation period, a series of linguistic tests was administered to determine the extent of his speech deficits. M.H. exhibited deficits in both languages, but the most severe deficits were seen only in Hebrew. In this language he had a severe difficulty in recalling words and names, so that his speech was non-fluent and interrupted by frequent pauses. He had difficulty understanding others' spoken Hebrew, and also had great difficulty reading and writing Hebrew. In Arabic, his native language, all of these abilities were affected only mildy.
  • The results support a neurolinguistic model in which the brain of bilinguals contains a semantic system (which represents word meanings) which is common to both languages and which is connected to independent lexical systems (which encode the vocabulary of each language). The findings further suggest that the second language (in this case, Hebrew) is represented by an independent subsystem which does not represent the first language (Arabic) and is more succeptible to brain damage.
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    A unique case study published in the open access journal Behavioral and Brain Functions sheds some light on this matter. The study, by Raphiq Ibrahim, a neurologist at the University of Haifa, describes a bilingual Arabic-Hebrew speaker who incurred brain damage following a viral infection. Consequently, the patient experienced severe deficits in Hebrew but not in Arabic. The findings support the view that specific components of a first and second language are represented by different substrates in the brain.
Tero Toivanen

AK's Rambling Thoughts: Nerve Cells and Glial Cells: Redefining the Foundation of Intel... - 0 views

  • Glia are generally divided into two broad classes, microglia and macroglia. Microglia are part of the immune system, specialized macrophages, and probably don't participate in information handling. Macroglia are present in both the peripheral and central nervous systems, in different types.
  • Traditionally, there were four types of glia in the CNS: astrocytes, oligodendrocytes, ependymal cells, and radial glia. Of these, the one type that's most important to the developing revolution in our ideas are those cells called astrocytes.2 It turns out that there are at least two types of cell (at least) subsumed under this name.24, 25, 31, 32 One, which retains the name of astrocyte, takes up neurotransmitters released by neurons (and glial cells), aids in osmoregulation,10 controls circulation in the brain,1, 31 and generally appears to provide support for the neurons and other types of glia.
  • Although both NG2-glia and astrocytes extend processes to nodes of Ranvier in white matter ([refs]) and synapses in grey matter, their geometric relationship to these neuronal elements is different. Thus, although astrocytes and NG2-glia bear a superficial resemblance, they are distinguished by their different process arborizations. This will reflect fundamental differences in the way these two glial cell populations interact with other elements in the neural network.
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  • Both types of glia are closely integrated with the nervous system, receiving information from action potentials via synapses22 (which, only a few years ago were thought to be limited to neurons), and returning control of neuron activity through release of neurotransmitters and other modulators. Both, then, demonstrate the potential for considerable intelligent activity, contributing to the overall intelligence of the brain.
  • Astrocytes probably (IMO) are limited, or mostly so, to maintaining the supplies of energy and necessary metabolites. They receive action potentials,3, 6 which allows them to closely and quickly monitor general activity and increase circulation in response, even before the neurons and NG2-glia have reduced their supply of ATP.21 They appear to be linked in a network among themselves,2, 5 allowing them to communicate their needs without interfering with the higher-level calculations of the brain.
  • NG2-glia appear to have several functions, but one of the most exciting things about them is that they seem to be able to fire action potentials.33 Their cell membranes, like those of the dendrites of neurons, have all the necessary channels and receptors to perform real-time electrical calculations in the same way as neural dendrites. They have also demonstrated the ability to learn through long term potentiation.
  • Dividing NG2-glia also retain the ability to fire action potentials, as well as receiving synaptic inputs from neurons.23 Presumably, they continue to perform their full function, including retaining any elements of long term potentiation or depression contained in their synapses.
  • Oligodendrocytes are responsible for the insulation of the axons, wrapping around approximately 1 mm of each of up to 50 axons within their reach, and forming the myelin sheath.
  • Although the precise type of neuron formed by maturing cells hasn't been determined, the very fact that cells of this type can change into neurons is very important. We actually don't know whether the cells that do this maturation are the same as those that perform neuron-like activities, there appear to be two separate types of NG2-glia, spiking and non-spiking.26 It may very well be that the "spiking" type have actually differentiated, while the "non-spiking" type may be doing the maturing. Of course, very few differentiated cell types remain capable of division, as even the "spiking" type do.
  • What's important about both dendrites and NG2-glia isn't so much their ability to propagate action potentials, as that their entire cell membranes are capable of "intelligent" manipulation of the voltage across it.
  • While there are many ion channels involved in controlling the voltage across the cell membrane, the only type we really need to worry about for action potentials is voltage-gated sodium channels. These are channels that sometimes allow sodium ions to pass through the cell membrane, which they will do because the concentration of sodium ions outside the cell is very much higher than inside. When and how much they open depends, among other things, on the voltage across the membrane.
  • A normal neuron will have a voltage of around -60 to -80mV (millivolts), in a direction that tends to push the sodium ions (which are positive) into the cell (the same direction as the concentration is pushing). When the voltage falls to around -55mV, the primary type of gate will open for a millisecond or so, after which it will close and rest for several milliseconds. It won't be able to open again until the voltage is somewhere between -55 and around -10mV. Meanwhile, the sodium current has caused the voltage to swing past zero to around +20mV.
  • When one part of the cell membrane is "depolarized" in this fashion, the voltage near it is also depressed. Thus, if the voltage is at zero at one point, it might be at -20mV 10 microns (μm) away, and -40mV 20μm away, and -60mV 30μm, and so on. Notice that somewhere between 20μm and 30μm, it has passed the threshold for the ion channels, which means that they are open, allowing a current that drives the voltage further down. This will produce a wave of voltage drop along the membrane, which is what the action potential is.
  • After the action potential has passed, and the gates have closed (see above), the voltage is recovered by diffusion of ions towards and away from the membrane, the opening of other gates (primarily potassium), and a set of pumps that push the ions back to their resting state. These pumps are mostly powered by the sodium gradient, except for the sodium/potassium pump that maintains it, which is powered by ATP.
  • the vast majority of calculation that goes into human intelligence takes place at the level of the network of dendrites and NG2-glia, with the whole system of axons, dendrites, and action potentials only carrying a tiny subset of the total information over long distances. This is especially important considering that the human brain has a much higher proportion of glial matter than our relatives.
  • This, in turn, suggests that our overall approach to understanding the brain has been far too axon centric, there needs to be a shift to a more membrane-centric approach to understanding how the brain creates intelligence.
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    Our traditional idea of how the brain works is based on the neuron: it fires action potentials, which travel along the axon and, when the reach the synapses, the receiving neuron performs a calculation that results in the decision when (or whether) to fire its own action potential. Thus, the brain, from a thinking point of view, is viewed as a network of neurons each performing its own calculation. This view, which I'm going to call the axon-centric view, is simplistic in many ways, and two recent papers add to it, pointing up the ways in which the glial cells of the brain participate in ongoing calculation as well as performing their more traditional support functions.
Tero Toivanen

The five ages of the brain: Adolescence - life - 04 April 2009 - New Scientist - 0 views

  • Jay Giedd at the National Institute of Mental Health in Bethesda, Maryland, and his colleagues have followed the progress of nearly 400 children, scanning many of them every two years as they grew up. They found that adolescence brings waves of grey-matter pruning, with teens losing about 1 per cent of their grey matter every year until their early 20s (Nature Neuroscience, vol 2, p 861).
  • This cerebral pruning trims unused neural connections that were overproduced in the childhood growth spurt, starting with the more basic sensory and motor areas.
  • Among the last to mature is the dorsolateral prefrontal cortex at the very front of the frontal lobe. This area is involved in control of impulses, judgement and decision-making, which might explain some of the less-than-stellar decisions made by your average teen. This area also acts to control and process emotional information sent from the amygdala - the fight or flight centre of gut reactions - which may account for the mercurial tempers of adolescents.
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  • These changes have both benefits and pitfalls. At this stage of life the brain is still childishly flexible, so we are still sponges for learning. On the other hand, the lack of impulse control may lead to risky behaviours such as drug and alcohol abuse, smoking and unprotected sex.
  • As grey matter is lost, though, the brain gains white matter
  • Substance abuse is particularly concerning, as brain imaging studies suggest that the motivation and reward circuitry in teen brains makes them almost hard-wired for addiction.
  • since drug abuse and stressful events - even a broken heart - have been linked to mood disorders later in life, this is the time when both are best avoided.
  • Making the most of this time is a matter of throwing all that teen energy into learning and new experiences - whether that means hitting the books, learning to express themselves through music or art, or exploring life by travelling the world.
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    Jay Giedd at the National Institute of Mental Health in Bethesda, Maryland, and his colleagues have followed the progress of nearly 400 children, scanning many of them every two years as they grew up. They found that adolescence brings waves of grey-matter pruning, with teens losing about 1 per cent of their grey matter every year until their early 20s (Nature Neuroscience, vol 2, p 861).
Tero Toivanen

First Evidence That Musical Training Affects Brain Development In Young Children - 0 views

  • The findings, published today (20 September 2006) in the online edition of the journal Brain [1], show that not only do the brains of musically-trained children respond to music in a different way to those of the untrained children, but also that the training improves their memory as well. After one year the musically trained children performed better in a memory test that is correlated with general intelligence skills such as literacy, verbal memory, visiospatial processing, mathematics and IQ.
  • Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
  • While previous studies have shown that older children given music lessons had greater improvements in IQ scores than children given drama lessons, this is the first study to identify these effects in brain-based measurements in young children.
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  • The researchers chose children being trained by the Suzuki method for several reasons: it ensured the children were all trained in the same way, were not selected for training according to their initial musical talent and had similar support from their families. In addition, because there was no early training in reading music, the Suzuki method provided the researchers with a good model of how training in auditory, sensory and motor activities induces changes in the cortex of the brain.
  • Analysis of the MEG responses showed that across all children, larger responses were seen to the violin tones than to the white noise, indicating that more cortical resources were put to processing meaningful sounds. In addition, the time that it took for the brain to respond to the sounds (the latency of certain MEG components) decreased over the year. This means that as children matured, the electrical conduction between neurons in their brains worked faster.
  • Of most interest, the Suzuki children showed a greater change over the year in response to violin tones in an MEG component (N250m) related to attention and sound discrimination than did the children not taking music lessons.
  • Analysis of the music tasks showed greater improvement over the year in melody, harmony and rhythm processing in the children studying music compared to those not studying music. General memory capacity also improved more in the children studying music than in those not studying music.
  • The finding of very rapid maturation of the N250m component to violin sounds in children taking music lessons fits with their large improvement on the memory test. It suggests that musical training is having an effect on how the brain gets wired for general cognitive functioning related to memory and attention.
  • It is clear that music is good for children's cognitive development and that music should be part of the pre-school and primary school curriculum.
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    Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
Tero Toivanen

Low Pessimism Protects Against Stroke: The Health and Social Support (HeSSup) Prospecti... - 2 views

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    It's good for your life and health to be optimist.
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    It' s a slightly different perspective that I' m enjoying at this time but I appreciate it may only be true for some-I' ve just begun to understand what "faith" means tho I' m not religious-still! (I feel some empathy now as to why people are) I feel much more inclined to just sit still and connect inside with the Source of me-any meditation or spiritual practice can lead me there or creativity,music too,nature! But to deliberately connect to the part of us all that is connected and knows/is All. From that place I' ve understood that theres noone to be, nowhere to go, nothing to do as we are all there already as we are all IT! So of course daily I forget this but this insight has gifted me much more optimism as I can assume that whatever I really ask for/intend/desire is already in the big melting pot that we can Life/God. That is ' faith' Ive realised now- to ask and know intimately that it' s already a given and to STOP Worrying and completely ignore the naysayers etc. It' s really trusting that I' m connected to it all and I am not separate. I' m beginning to observe quite distinctly the thoughts that separate me from what I want/intend. Particularly in relation to my fellow beings! But then I turn to the place that is connected and I feel so good! and just thinking of the situation from that place and holding that good feeling in relation and giving it over (the problem) really helps! I know several spiritual teachers have said "give it over to me". I' m starting to understand it really is that simple. Trying hard and worrying just create such muck and mire! This may be part of the surrender letting go and letting God that others speak of also? I reckon it would be interesting to see where how people get there faith/trust in life that creates the underlying optimism. What gives that to them? I remember as a child I had it naturally I often got what I asked for and intended and there was an abundance of flow and optimism. No resistance. Fear and doubt come later
Tero Toivanen

Brain Stimulant: Brain Chip to Restore Functioning from Damage - 1 views

  • The ReNaChip project is developing electronic biomimetic technology that could serve to replace damaged or missing brain tissue. This is basically neuromorphic engineering that seeks to mimic how neurons function. In the future this may be useful for people who have had injuries due to stroke or other illnesses.
  • The objective of this project is to develop a full biohybrid rehabilitation and substitution methodology; replacing the aged cerebellar brain circuit with a biomimetic chip bidirectionally interfaced to the inputs and outputs of the system. Information processing will interface with the cerebellum to actuate a normal, real-time functional behavioural recovery, providing a proof-of-concept test for the functional rehabilitation of more complex neuronal systems.
  • A sophisticated exocortex could potentially allow a two way communication between the external apparatus and the mind. The contraption could essentially scale up the amount of neurons in your brain by an artificial means. Most likely it would be used to improved the disabled first, with other applications being more speculative possibilities.
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    The ReNaChip project is developing electronic biomimetic technology that could serve to replace damaged or missing brain tissue. This is basically neuromorphic engineering that seeks to mimic how neurons function. In the future this may be useful for people who have had injuries due to stroke or other illnesses.
Tero Toivanen

Adult Learning - Neuroscience - How to Train the Aging Brain - NYTimes.com - 1 views

  • One explanation for how this occurs comes from Deborah M. Burke, a professor of psychology at Pomona College in California. Dr. Burke has done research on “tots,” those tip-of-the-tongue times when you know something but can’t quite call it to mind. Dr. Burke’s research shows that such incidents increase in part because neural connections, which receive, process and transmit information, can weaken with disuse or age.
  • But she also finds that if you are primed with sounds that are close to those you’re trying to remember — say someone talks about cherry pits as you try to recall Brad Pitt’s name — suddenly the lost name will pop into mind. The similarity in sounds can jump-start a limp brain connection. (It also sometimes works to silently run through the alphabet until landing on the first letter of the wayward word.)
  • Recently, researchers have found even more positive news. The brain, as it traverses middle age, gets better at recognizing the central idea, the big picture. If kept in good shape, the brain can continue to build pathways that help its owner recognize patterns and, as a consequence, see significance and even solutions much faster than a young person can.
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  • The trick is finding ways to keep brain connections in good condition and to grow more of them.
  • Educators say that, for adults, one way to nudge neurons in the right direction is to challenge the very assumptions they have worked so hard to accumulate while young. With a brain already full of well-connected pathways, adult learners should “jiggle their synapses a bit” by confronting thoughts that are contrary to their own, says Dr. Taylor, who is 66.
  • Teaching new facts should not be the focus of adult education, she says. Instead, continued brain development and a richer form of learning may require that you “bump up against people and ideas” that are different. In a history class, that might mean reading multiple viewpoints, and then prying open brain networks by reflecting on how what was learned has changed your view of the world.
  • Such stretching is exactly what scientists say best keeps a brain in tune: get out of the comfort zone to push and nourish your brain. Do anything from learning a foreign language to taking a different route to work.
  • “As adults we have these well-trodden paths in our synapses,” Dr. Taylor says. “We have to crack the cognitive egg and scramble it up. And if you learn something this way, when you think of it again you’ll have an overlay of complexity you didn’t have before — and help your brain keep developing as well.”
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    Dr. Burke has done research on "tots," those tip-of-the-tongue times when you know something but can't quite call it to mind. Dr. Burke's research shows that such incidents increase in part because neural connections, which receive, process and transmit information, can weaken with disuse or age.
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