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Assunta Krehl

Toronto's $25 million commercialization "engine" celebrates the appointment of its Boar... - 0 views

  • MaRS Innovation is honoured to announce its permanent Board of Directors, who brings together a remarkable and broad set of experiences and networks to support the development of this dynamic partnership of Toronto research institutions.  Designed to enhance the commercial output of Toronto’s world-leading research cluster, MaRS Innovation is positioned to make a significant contribution to Canada’s innovation economy and the quality of life for Canadians and others around the world.
  • upported by the Government of Canada through the Centres of Excellence in Research and Commercialization (CECR) program, and its member institutions, MaRS Innovation is focused on converting important discoveries into a new generation of products, services and high value jobs. The newly appointed Board of Directors, which includes academic and business leaders from across Canada and the United States, has the targeted expertise to guide MaRS Innovation to deliver on this critical mission.   MaRS Innovation represents a unique collaborative model, which aggregates the exceptional discovery pipeline of 14 leading Toronto academic institutions to build a diversified portfolio of assets, and harness the economic and job creation potential of the best opportunities for Toronto, Ontario and Canada.
  • “MaRS Innovation is privileged to announce a Board of Directors of this caliber and breadth of skill,” said Mary Jo Haddad, Chair of the MaRS Innovation Board and President and CEO of The Hospital for Sick Children. “The collective experience and guidance of these individuals will be critical to developing a collaborative, integrated and agile approach to this transformational organization that will move Canada into its next phase of economic development.”
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  • W. Geoffrey Beattie – Deputy Chairman & President, Woodbridge Company Limited, Thomson Reuters Corporation, Toronto Christopher C. Capelli – Vice President, Technology Based Ventures, Office of Technology Commercialization, University of Texas, M.D. Anderson Cancer Center, Houston, TX Ron Close – Information technology entrepreneur, Entrepreneur-in-Residence, MaRS, and Executive Entrepreneur-in-Residence, The Richard Ivey School of Business, The University of Western Ontario, London, ON Nicholas Darby – Formerly Director of Physical Sciences, Corporate Venture Capital, Dow Chemical Company, President, Darby & Associates Consulting LLC, Midland, MI  Mary Jo Haddad – President & CEO, The Hospital for Sick Children, Toronto Jacqueline H.R. Le Saux – Former General Counsel, North America and Corporate Secretary, Patheon, Inc., Toronto David A. Leslie - Chair, Sunnybrook Health Sciences Centre, and Former Chairman & CEO, Ernst & Young, Toronto Michael H. May – President & CEO, Rimon Therapeutics, Toronto Chandra J. Panchal – Founder, President & CEO, Axcelon Biopolymers Corp., Dollard-des-Ormeaux, QC Ilse Treurnicht – CEO, MaRS Discovery District, Toronto Donald A. Wright – President & CEO, The Winnington Capital Group Inc., Toronto
  • MaRS Innovation serves as a business accelerator platform with a single point of entry for industry partners and investors.  It will increase the scale, scope and viability of IP offerings, and the quantity and quality of deal flow from partner institutions.  MaRS Innovation will also facilitate strategic research collaborations with industry partners, strengthen the innovation capacity of Canadian industry through adoption of new technologies from its member institutions, and launch a new generation of robust, high-growth Canadian companies that will become global market leaders.   The quality of the combined discovery pipeline will catalyze and attract sources of risk capital for translational research, market validation, company formation and growth.  “MaRS Innovation represents a unique and timely platform to contribute in a meaningful way to Canada’s knowledge economy, leveraging Toronto’s remarkable research excellence.  The vision and serious commitment of its members to work together to transform our commercialization results, and the support of the Federal Government, made this possible.  The announcement of this outstanding group of leaders to the Board of Directors for MaRS Innovation is an exciting step forward,” said Ilse Treurnicht, MaRS CEO and interim Managing Director of MaRS Innovation.
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    MaRS Innovation announced its permanent Board of Directors. MaRS Innovation is focused on converting important discoveries into a new generation of products, services and high value jobs.
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    MaRS Innovation announced its permanent Board of Directors. MaRS Innovation is focused on converting important discoveries into a new generation of products, services and high value jobs. Feb 6, 2009
Assunta Krehl

Pharmafocus.com - 0 views

  • Canada has always had to fight hard to attract talent and investment
  • MaRS Vital to Toronto's life sciences vision is MaRS (derived from Medical and Related Sciences) a non-profit organisation and business centre located in the heart of the city. Its core function is as a biotech incubator and business park, known as MaRS Discovery District. The venture was first established in 2000 to help foster and accelerate the growth of successful Canadian businesses and, after some uncertain times, it is now gathering momentum. A separate technology transfer office, MaRS Innovation, has also been established that, it is hoped, can be a world beater in its own right (see Turning good ideas into world beaters below). The location of the MaRS building in central Toronto is important, as it is just a stone's throw away from an existing cluster of universities and academic hospitals. MaRS has many links with other research-based organisations, including collaborations with three local universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS occupies the Old Toronto general hospital, where insulin was first discovered by Best and Banting in 1921 and then developed for use in human trials. The 21st Century organisation can build on this heritage in patient-focused discovery and development. Formerly the head of venture capital firm Primaxis, Ilse Treurnicht is chief executive of MaRS Discovery District. She acknowledges the crisis in venture capital funding, and says Canada's sector has always had less access funds through this route than other countries. This is one of the drivers behind the search for a new approach. Treurnicht says the old models of building biotech and life sciences businesses have to be discarded, as they have failed to build companies with critical mass. She says MaRS' new 'Convergence Innovation' strategy of bringing science, capital and business together will pay off.
  • "We call our strategy 'Convergence Innovation' and what we are trying to do is move away from the old linear model of academics struggling in their spare time to build companies or entrepreneurs doing this in a very incremental way."It takes time and it has many risk points along the way. So using this Convergence centre model to create a much more dynamic organisation which can help accelerate good ideas towards the commercialisation." But she says Canada's geography and demographics are always going to be a challenge. "This is a very large country with a small population. If you think in terms of clusters and hub regions, Canada's business hubs are separated geographically, and there is not much in between in terms of people."That means we can't try to be a little United States, because we just won't show up on the radar. We have to take a different approach. We have to think about collaboration as our potential competitive advantage - that means using networks and associations to solve problems and build businesses."So as new opportunities emerge, we can take them to market faster and hopefully with a higher success rate." The centre currently accommodates numerous start up companies, as well as those providing legal and financial services to them. AstraZeneca and GlaxoSmithKline also have offices on site. In all, MaRS provides mentoring for over 200 different companies across Ontario, and runs courses on entrepreneurship and preparing products for market.
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  • Transition Therapeutics is one of the companies based at MaRS, and is an example of a biopharmaceutical company that is taking a new approach to the science and business of drug development.
  • Now Toronto's MaRS Innovation (MI) has been launched to try to guide and accelerate these promising ideas out of the wilderness and onto the market. MI is a not-for-profit technology transfer company that will channel all the best ideas to come out of Toronto's renowned academic centres. In the Toronto and Ontario area there were between 14-16 different technology transfer offices in the different institutions, and MaRS Innovation resolved to bring these interests together into a single entity after industry partners told them it was an inefficient way to do business. Bringing together the different institutions under one umbrella organisation has been an arduous task for MaRS, but the reward could be considerable for all parties. MI now oversees probably the largest intellectual property pipeline of its kind, representing about $1 billion in annual research spending. This means MI will be a unified route for all of Toronto's academics and their institutions when they want to develop and commercialise a bright idea. Most importantly, investors from industry who are looking to collaborate will now be able to deal with just organisation and one IP process. MI will cover patentable ideas across a broad range of areas, and not just life sciences - the discovery pipeline in physical sciences, information and communication technology, and green technology ('cleantech') will all be funnelled through MI. MI now represents three universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS Innovation, with support from MaRS and BioDiscovery Toronto, will advance commercialisation through industry partnerships, licensing and company creation.
  • ts chief executive is Dr Rafi Hofstein. Hofstein has been headhunted from Israel where he was chief executive of Hadasit, the technology transfer company of the Hadassah Medical Organization in Jerusalem and chair of the publicly-traded company Hadasit BioHolding. He brings this considerable experience in technology transfer to what he thinks is a groundbreaking enterprise."MaRS Innovation is a unique global initiative, and I must commend the institutional leaders in Toronto for pulling this innovation powerhouse together to strengthen commercialisation output." He adds: "I believe this is going to modernise the whole notion of tech transfer." He says the scale and diversity of MaRS Innovation's remit puts it into a league of its own. Other research clusters elsewhere in the world have attempted similar projects before, but have been thwarted by the difficulty in bringing parties together. MaRS Innovation will also help launch and grow new spin-off companies and incubate them for 2-3 years to ensure a strong commercial footing. Hofstein says MI will also fund proof of concept trials which will persuade major pharma companies to invest in their development.
  • MI has just announced its first two commercialisation deals with academic partners in the city. The first is with the Samuel Lunenfeld Research Institute of Mount Sinai Hospital to develop stem cell from umbilical cords to treat cardiovascular disease, diabetes and neurological disorders. "With the Toronto area identified as a world-leading cluster in stem cell research, we are extremely excited to have identified this technology as our first commercialisation opportunity," said Dr Hofstein.
  • "Our partnership with MaRS Innovation on developing methods for using stem cells for diseases such as diabetes will allow us to work towards advancing care for these critical conditions."
  • The second collaboration is between MI and The University of Toronto (U of T) and involves a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers. "There are 300 million diabetics worldwide, of which some 15% develop troublesome foot ulcers. This wound healing technology is extremely exciting, making it an early commercialisation opportunity that MaRS Innovation has identified as being a potential win for some 45 million diabetics globally," said Dr Hofstein.
  • "This is one of many new commercialisation ventures that will be initiated by MaRS Innovation, our partner in commercialisation of research with 13 other academic institutions across the Greater Toronto Area," said Paul Young, U of T's vice-president, Research. "We at U of T are delighted that this innovation from Dr Lee will be taken to the marketplace to the benefit of society and the economy of Ontario and Canada." By aggregating the leading edge science of its institutional members and being a one-stop commercialisation centre for industry, entrepreneurs and investors, MI could really help put Toronto and Canada on the map."MaRS Innovation is deeply committed to facilitating strategic research collaborations with industry partners, strengthening the innovation capacity of Canadian industry through adoption of new technologies, and launching a new generation of robust, high-growth Canadian companies that will become global market leaders," added Dr Hofstein. "We look forward to working closely with all of our institutional members and to continue to jointly announce exciting commercial opportunities."
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    Canada has always had to fight hard to attract talent and investment. As stated in Pharmafocus.com, "MaRS Discovery District helps to foster and accelerate the growth of successful Canadian businesses." MaRS Innovation has also been launched to accelerate ideas onto the market.
Assunta Krehl

globeadvisor.com: HOW A GOOD PLAN WENT BAD - 0 views

  • University of Toronto Asset Management
  • Canada's sharpest financial minds
  • runs $2.8-billion of staff pensions and $1.5-billion of endowments, which traditionally produces tens of millions of dollars annually for student aid and faculty posts.
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  • But this year the money has stopped flowing after investment losses reached $1.5-billion for 2008 and the university was forced to cancel a planned $62-million endowment payout, representing about 5 per cent of its operating budget.
  • Canada's most innovative investment funds is in question by the university that is bearing the brunt of its losses.
  • Settling into a boardroom chair in the restored heritage building of Toronto's MaRS research centre, Mr. Moriarty remains unshaken by the crisis. He stands committed to UTAM's sophisticated investing approach, reciting phrases like "portable alpha" and "risk budgets" to explain portfolio decisions.
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    University of Toronto remodelled its pension and endowment fund - and then lost $1.5-billion last year. University of Toronto Asset Management runs $2.8-billion of staff pensions and $1.5-billion of endowments, which traditionally produces tens of millions of dollars annually for student aid and faculty posts.runs $2.8-billion of staff pensions and $1.5-billion of endowments, which traditionally produces tens of millions of dollars annually for student aid and faculty posts. Small mention of UTAM at MaRS.
Assunta Krehl

MaRS Discovery District - News - News Releases - 2009 - MaRS Innovation selects diabeti... - 0 views

  • MaRS Innovation and The University of Toronto (U of T) are pleased to announce that they have entered into an agreement to collaboratively commercialize a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers. 
  • This wound healing technology is extremely exciting, making it an early commercialization opportunity that MaRS Innovation has identified as being a potential win for some 45 million diabetics globally,” said Dr. Rafi Hofstein, President and CEO of MaRS Innovation. 
  • disruptive technology that facilitates continued therapeutic release of NO over a two week period has been developed by Dr. Ping Lee, Professor at the Leslie Dan Faculty of Pharmacy and GlaxoSmithKline Chair in Pharmaceutics and Drug Delivery at U of T.
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  • This is one of many new commercilization ventures that will be initiated by MaRS Innovation, our partner in commercialization of research with 13 other academic institutions across the Greater Toronto Area,” said Paul Young, U of T’s Vice-President, Research. “We at U of T are delighted that this innovation from Dr. Lee will be taken to the marketplace to the benefit of society and the economy of Ontario and Canada.” 
  • With the launch of this second commercial opportunity, MaRS Innovation will continue to aggregate the exceptional science of its institutional members by being a one-stop commercialization centre for industry, entrepreneurs and investors. MaRS Innovation is expediting the transformation of the Toronto-based research into a powerful commercialization engine. 
  • “MaRS Innovation is deeply committed to facilitating strategic research collaborations with industry partners, strengthening the innovation capacity of Canadian industry through adoption of new technologies, and launching a new generation of robust, high-growth Canadian companies that will become global market leaders,” added Dr. Hofstein. “We look forward to working closely with all of our institutional members and to continue to jointly announce exciting commercial opportunities.”
  • MaRS Innovation is dedicated to bringing brilliant discoveries to market by converting the outstanding science of its member institutions into outstanding economic results for Canada and the world.
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    MaRS Innovation and The University of Toronto (U of T) announce that they have entered into an agreement to collaboratively commercialize a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers.
Assunta Krehl

Want to learn about innovation? Head to Toronto - Business Innovation Factory - 0 views

  • Probably most impressive was The MaRS Centre - an old hospital converted into a non-profit innovation centre connecting science, technology and social entrepreneurs with business skills, networks and capital. The building is undeniably cool. Located in Toronto’s “Discovery District” -- two square kilometres have been designated as the city’s center of innovation. The MaRS Centre is a gateway of sorts to Canada’s largest concentration of scientific research. It’s anchored by major teaching hospitals, the University of Toronto and more than two dozen affiliated research institutes.
  • MaRS Centre from the outside
  • MaRS was created in 2000. The founding group raised significant capital (almost $100 million from all three levels of government and both institutional and individual private sector donors and an additional $130 million of debt and credit lease instruments were also secured) to support the development. What’s so clear is that leadership to drive public/private sector collaboration is required to effect real change. Many credit Ontario Premier Dalton McGuinty for helping to not only create the MaRS Centre but also invigorate the region as a whole.
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  • Martin has transformed the Rotman School from a mediocre Canadian business school to a world-class institution. It’s one of the few business schools around with an innovative curriculum built around the fundamentals of design thinking. Martin believes designers approaches to thinking and problem-solving can and should be applied to all components of business (He calls it integrative thinking and business design.) Most of our own processes here at the Business Innovation Factory are firmly rooted in design thinking principles.
  • Martin also managed to lure Richard Florida to Toronto in 2007 to direct the Rotman School's new $120-million Martin Prosperity Institute. Spinning off from much of Florida's research, the institute's goal is to build a leading think-tank on the role of sub-national factors – location, place and city-regions – in global economic prosperity. By taking an integrated view of prosperity, the institute will look beyond economic measures to include the importance of quality of place and the development of people’s creative potential. I'm looking forward to ongoing conversations with our new friends at the Rotman school. I suspect there might even be a collaboration or two about to happen as well. Bottom line: if you want to learn about innovation, Toronto is the place to be.
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    Chris Flanagan talks about the benefits of moving to Toronto and the great work happening at the MaRS Centre. Mention of Martin transforming the Rotman School to a "world-class institution" ... that has "an innovative curriculum built around the fundamentals of design thinking." There is also a mention of the Martin Prosperity Institute spin off.
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    Chris Flanagan talks about the benefits of moving to Toronto and the great work happening at the MaRS Centre. Mention of Martin transforming the Rotman School to a "world-class institution" ... that has "an innovative curriculum built around the fundamentals of design thinking." There is also a mention of the Martin Prosperity Institute spin off. Oct 30, 2008
Assunta Krehl

Look who just landed on MaRS - The Globe and Mail - 0 views

  • Look who just landed on MaRS
  • MaRS was known for just that – putting a collective roof over the heads of Canada's out-of-this-universe thinkers. Aside from hosting the unlikely duo of Arnold Schwarzenegger and Dalton McGuinty at a funding announcement two years ago, the centre seems enveloped in galactic silence.
  • corner of College and University
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  • the country's most significant collection of scientific and medical researchers.
  • This week, a program called MaRS Innovation announced the appointment of its first full-time president, Raphael (Rafi) Hofstein, a Harvard-trained, Israeli biomedical wizard who wants to bring together companies, scientists and funding under one roof to create a special alchemy of science and shekels.
  • Since its inception, MaRS has focused on turning big ideas into commercial projects. The difference between the two entities is that pretty much anyone with an idea or discovery could come to MaRS for support, regardless of whether they had their “eureka” moment in a state-of-the-art research lab or in their garage. MaRS Innovation, a separate endeavour with its own board of directors, only works with researchers from its 14 partner institutions, which include some of the most prestigious universities and hospitals in Canada. The goal of that project is to do the kind of work those institutions would normally try to do in-house, but on a bigger scale and, the project's backers hope, with better results.
  • MaRS Innovation is very much in its infancy. Officially launched last June, the project is barely a year old, and the board of directors was only announced this February. It has secured about $25-million in funding over five years to be used for commercialization of projects.
  • Dr. Hofstein is giving himself two to three years to roll out a success story – be it the creation of a new small company founded on the back of a researcher's drug discovery and funded by a big pharmaceutical firm, or a new discovery that, packaged properly, attracts serious venture-capital money.
  • The federal government has also taken notice, naming MaRS Innovation as one of 11 new “Centres of Excellence for Commercialization and Research,” a designation that came with almost $15-million in funding.
  • California Governor Arnold Schwarzenegger speaks at MaRs with Premier Dalton McGuinty after a tour of the building in 2007.
  • Indeed, the MaRS Innovation model of pushing for commercial applications of research seems to be directly in line with the philosophy of the Conservative government, which clearly favours practical results when it comes to funding for scientific research.
  • But those tasks involve two separate skill sets, Mr. Tabrizi suggests, and may be much better suited to a place such as MaRS, where academic and industry heavyweights converge.
  • Many of MaRS's biggest partners are in health care, and Dr. Hofstein is jumping in with a list of priorities that includes focusing on stem-cell research and oncology.
  • MaRS itself has always been good at bringing people from various sectors together, but there's no guarantee that Dr. Hofstein's plan will work, especially in the two-to-three-year timeline he mentions when talking about a rollout date for the first MaRS Innovation projects.
  • Indeed, Mr. Tabrizi says some Silicon Valley insiders marvel at what MaRS Innovation is trying to do. “I think there's something innovative there,” he says. “Something different is being done.”
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    MaRS Innovation announced the appointment of its first full-time president, Raphael (Rafi) Hofstein.
Sarah Hickman

The Double Helix: A Personal Account of the Discovery of the Structure of DNA: Amazon.c... - 0 views

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    By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
Assunta Krehl

MobileMonday partners with MaRS to inform and connect wireless professionals - MaRSdd.com - 0 views

  • MobileMonday Toronto and MaRS are delighted to announce a partnership to develop and host a range of dynamic events for the city’s mobile industry professionals. MobileMonday at MaRS will offer thought leadership and critical industry perspectives – most recently from a senior manager at Research in Motion – while connecting top-tier professionals and boosting the profile of one of the fastest-growing sectors of communications technology.
  • “MaRS is a fantastic environment for sharing ideas and industry knowledge, two key building blocks of the MobileMonday community,” said Jim Brown and Alexander S. Bosika, co-founders of the MobileMonday Toronto chapter. “MaRS and its network of business advisors and capital providers are also of great benefit to many of our members who are developing business plans and seeking capital.”
  • For MaRS, the partnership is a natural fit with great potential to benefit the hundreds of start-up clients from across Ontario who are working hard to turn their innovative concepts into viable, thriving businesses, and come to MaRS for advice and connections to potential customers and investors. 
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  • We’re very excited to be working closer with the MobileMonday community,” said MaRS CEO Ilse Treurnicht. “As MobileMonday Toronto moves to MaRS, it helps us connect with additional intellectual capital in one of the most significant high-growth sectors of the new economy.”
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    MobileMonday Toronto and MaRS announced a partnership to develop and host a range of dynamic events for the city's mobile industry professionals. MobileMonday at MaRS will offer thought leadership and critical industry perspectives and connect top-tier professionals and boosting the profile of one of the fastest-growing sectors of communications technology.
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    MobileMonday Toronto and MaRS announced a partnership to develop and host a range of dynamic events for the city's mobile industry professionals. MobileMonday at MaRS will offer thought leadership and critical industry perspectives and connect top-tier professionals and boosting the profile of one of the fastest-growing sectors of communications technology. Feb 17, 2009
Assunta Krehl

Test-tube industry - Canadian Business - 0 views

  • For Dr. John Evans, growing a strong biotechnology industry is much the same: cities must provide a nurturing environment where science and business can thrive together.
  • That's why Evans, former president of the University of Toronto and current chairman of Torstar Corp., is spearheading the $345-million Medical and Related Science initiative, or MaRS--a petri dish of sorts for commercializing science research. "A lot of intellectual property is being commercialized outside Canada," says Evans. "I think we've been slow in realizing just how important technology developments are to the economic future of the country. MaRS is an attempt to give this a kick into a higher gear." The centrepiece of the MaRS plan, which will officially launch May 12, is a 1.3-million-square-foot, five-building complex in downtown Toronto that will provide office and lab space for small and medium-size companies and incubators, including the not-for-profit Toronto Biotechnology Commercialization Centre. While Evans is reluctant to limit its scope, MaRS will generally focus on health-related technologies, from new drugs and genetic treatments to medical devices and imaging software. Branded a "convergence centre," it will also house a careful mix of support services: intellectual property lawyers, accountants, marketing experts, government funding organizations and venture capital financiers. Plus, start-ups will have access to all the latest equipment on site. For instance, MaRS is in talks with MDS Sciex to supply mass spectrometers, used in proteomics research.
  • But MaRS will be more than just a New Economy real estate development. Evans's intention is to funnel tenants' rent money into services--such as entrepreneurship seminars and angel-matching programs--that MaRS will offer to the broader biotech community. That's why MaRS's location is key: the centre will be built in the heart of what Toronto has dubbed the "Discovery District," a two-square-kilometre chunk of the downtown core, encompassing U of T and four major hospitals. From there, MaRS hopes to act as a network hub across Ontario, with links to research-intensive universities. "None of them," says Evans, "have the critical mass to put it all together on their own."
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  • MaRS's primary goal is to get Toronto and the rest of Ontario on the global biotech map. Evans came up with the concept in the late 1990s with Dr. Calvin Stiller, CEO of the labor-sponsored Canadian Medical Discoveries Fund, and Kenneth Knox, a former deputy minister for the Ontario government who's now CEO of MaRS
  • As far as schemes to support fledgling industries go, MaRS is refreshing. To start, it's a nonprofit corporation, not a government program, which will hopefully ensure that it runs more efficiently. The feds and the province of Ontario have each doled out $20 million for MaRS, and Toronto has donated in-kind $4.5 million. More than $12 million has come from a small pool of corporations, including Eli Lilly Canada and MDS, as well as individual donors like Joseph Rotman and Lawrence Bloomberg (who both sit on the MaRS board). U of T pitched in $5 million, and MaRS also did some innovative bond financing to round off the $165 million needed to build Phase I. "It was very important for us to not belong to anybody," says Evans.
  • Now MaRS's challenge is to get the word out. Its posted rate of $26 per square foot is very competitive for prime downtown real estate and is sure to attract attention, especially considering its customized lab space. But MaRS's success won't be measured by a low vacancy rate; getting the right mix of scientists, entrepreneurs and professionals is critical if it plans to commercialize some sustainable businesses. It won't happen overnight--in fact, it may be 10 years before anyone can gauge MaRS's impact. Seems growing a biotech industry isn't quite as easy as growing E. coli in a petri dish.
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    John Evans spearheads the MaRS project which will help to accelerate commercialization for scientific research. The official launch of the MaRS plan will happen on May 12, 2003.
Tim T

How to Make Wealth - 0 views

  • Remember what a startup is, economically: a way of saying, I want to work faster. Instead of accumulating money slowly by being paid a regular wage for fifty years, I want to get it over with as soon as possible. So governments that forbid you to accumulate wealth are in effect decreeing that you work slowly. They're willing to let you earn $3 million over fifty years, but they're not willing to let you work so hard that you can do it in two. They are like the corporate boss that you can't go to and say, I want to work ten times as hard, so please pay me ten times a much. Except this is not a boss you can escape by starting your own company.
  • What is technology? It's technique. It's the way we all do things. And when you discover a new way to do things, its value is multiplied by all the people who use it. It is the proverbial fishing rod, rather than the fish. That's the difference between a startup and a restaurant or a barber shop. You fry eggs or cut hair one customer at a time. Whereas if you solve a technical problem that a lot of people care about, you help everyone who uses your solution. That's leverage.If you look at history, it seems that most people who got rich by creating wealth did it by developing new technology. You just can't fry eggs or cut hair fast enough. What made the Florentines rich in 1200 was the discovery of new techniques for making the high-tech product of the time, fine woven cloth. What made the Dutch rich in 1600 was the discovery of shipbuilding and navigation techniques that enabled them to dominate the seas of the Far East.
  • What a company does, and has to do if it wants to continue to exist, is earn money. And the way most companies make money is by creating wealth. Companies can be so specialized that this similarity is concealed, but it is not only manufacturing companies that create wealth. A big component of wealth is location. Remember that magic machine that could make you cars and cook you dinner and so on? It would not be so useful if it delivered your dinner to a random location in central Asia. If wealth means what people want, companies that move things also create wealth. Ditto for many other kinds of companies that don't make anything physical. Nearly all companies exist to do something people want.And that's what you do, as well, when you go to work for a company. But here there is another layer that tends to obscure the underlying reality. In a company, the work you do is averaged together with a lot of other people's. You may not even be aware you're doing something people want. Your contribution may be indirect. But the company as a whole must be giving people something they want, or they won't make any money. And if they are paying you x dollars a year, then on average you must be contributing at least x dollars a year worth of work, or the company will be spending more than it makes, and will go out of business.Someone graduating from college thinks, and is told, that he needs to get a job, as if the important thing were becoming a member of an institution. A more direct way to put it would be: you need to start doing something people want. You don't need to join a company to do that. All a company is is a group of people working together to do something people want. It's doing something people want that matters, not joining the group.
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  • When wealth is talked about in this context, it is often described as a pie. "You can't make the pie larger," say politicians. When you're talking about the amount of money in one family's bank account, or the amount available to a government from one year's tax revenue, this is true. If one person gets more, someone else has to get less.I can remember believing, as a child, that if a few rich people had all the money, it left less for everyone else. Many people seem to continue to believe something like this well into adulthood. This fallacy is usually there in the background when you hear someone talking about how x percent of the population have y percent of the wealth. If you plan to start a startup, then whether you realize it or not, you're planning to disprove the Pie Fallacy.What leads people astray here is the abstraction of money. Money is not wealth. It's just something we use to move wealth around. So although there may be, in certain specific moments (like your family, this month) a fixed amount of money available to trade with other people for things you want, there is not a fixed amount of wealth in the world. You can make more wealth. Wealth has been getting created and destroyed (but on balance, created) for all of human history.Suppose you own a beat-up old car. Instead of sitting on your butt next summer, you could spend the time restoring your car to pristine condition. In doing so you create wealth. The world is-- and you specifically are-- one pristine old car the richer. And not just in some metaphorical way. If you sell your car, you'll get more for it.In restoring your old car you have made yourself richer. You haven't made anyone else poorer. So there is obviously not a fixed pie. And in fact, when you look at it this way, you wonder why anyone would think there was.
Assunta Krehl

Toronto Region Immigrant Employment Council appoints Gordon M. Nixon and Zabeen Hirji a... - 0 views

  • The Toronto Region Immigrant Employment Council (TRIEC) is pleased to announce today's appointment of Gordon M. Nixon, president and chief executive officer of RBC, as Chair, and Zabeen Hirji, chief human resources officer of RBC, as Co-Chair of TRIEC.
  • As top executives at one of the largest financial institutions in North America, Gord Nixon and Zabeen Hirji are key ambassadors to articulate how Canadian companies can benefit from the international experience and networks, language skills and cultural knowledge that skilled immigrants bring with them to Canada."
  • Nixon has for years been a champion for promoting diversity in Canadian communities and of leveraging skilled immigrant talent as a driver of Canadian innovation and prosperity. Nixon is chairman of the Canadian Council of Chief Executives and chairman of MaRS Discovery District. In 2007, Nixon was invested into the Order of Ontario and was named Canada's Outstanding CEO of the Year.
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    The Toronto Region Immigrant Employment Council (TRIEC) is pleased to announce today's appointment of Gordon M. Nixon, president and chief executive officer of RBC, as Chair, and Zabeen Hirji, chief human resources officer of RBC, as Co-Chair of TRIEC. Sept 10, 2009
Sarah Hickman

Smart World: Amazon.ca: Richard Ogle: Books - 0 views

  •  
    Since ancient times, people have believed that breakthrough ideas come from the brains of geniuses with awesome rational powers. In recent years, however, the paradigm has begun to shift toward the notion that the source of creativity lies "out there," in the network of connections between people and ideas. In this provocative book, Richard Ogle crystallizes the nature of this shift, and boldly outlines "a new science of ideas." The key resides in what he calls "idea-spaces," a set of nodes in a network of people (and their ideas) that cohere and take on a distinctive set of characteristics leading to the generation of breakthrough ideas. These spaces are governed by nine laws--illuminated in individual chapters with fascinating stories of dramatic breakthroughs in science, business, and art. "Smart World" will change forever the way we think about creativity and innovation.
Assunta Krehl

reportonbusiness.com: THE COMPANY: INFONAUT INC.: Charting the right course through an ... - 0 views

  • Toronto, where a small firm is using 21st-century software to create maps with similar goals - the containment of disease - by showing infection patterns that can be understood at a glance.
  • Toronto, where a small firm is using 21st-century software to create maps with similar goals - the containment of disease - by showing infection patterns that can be understood at a glance.
  • There's nothing wrong with Infonaut using the H1N1 flu outbreak to gain exposure, as long as the company is careful in the tone it takes, said John Lute, president of Toronto communications firm Lute and Co.
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  • Infonaut Inc. chief executive officer Niall Wallace and his partner, chief operating officer Matt McPherson, both former IT consultants for the Ontario government, created the company after helping to craft some of the recommendations that resulted from the SARS outbreak of 2003. They understood the value of visually represented, real-time infection data, and left government to set up Infonaut to develop that technology.
  • Infonaut has created three software products that turn infection information into maps. All are being tested in pilot projects and will soon be marketed commercially.
  • One, called Infection Watch Live, is now taking data gathered at 14 hospital emergency rooms in eastern Ontario and using it to create publicly accessible maps that show exactly where in the region cases of influenza and gastrointestinal diseases are active.
  • This complex mapping can help monitor and stop the spread of C. difficile and other superbugs.
  • The third product, called Regional Watch Live, generates maps and reports for regional health professionals by merging lab test results with a range of other information.
  • INFONAUT INC
  • Make sure to present straightforward information about how the company's products might help mitigate an outbreak in the future, but do not exaggerate promises. Be upfront about the state of pilot tests, the timelines to get the software to market, and how much funding will be needed to go to full commercialization. Use respected third-party partners to endorse the products, a move that will give the company more credibility. If there are privacy concerns, spell them out and detail how they are being addressed.
  • Infonaut should ensure that its message is understated and that the company is not an "ambulance chaser," Mr. Lute said
  • But the company does need to give straightforward information about how its products might help mitigate an outbreak in the future, and not exaggerate its promises, she said. In particular, it needs to be upfront about the state of its pilot tests and include details of when full versions of its products will be available. It also must explain how much funding they will need to get there, Ms. Wilcox said.
  • With Infonaut, there seems to be no question that there is a public gain, he said. "If it is just an opportunistic attempt to cash in on the misfortune of others, that tends to play badly. Where a company has something that can be tied to the public interest, such as in this case ... it is very low-risk."
  • He suggests that Infonaut make good use of its pilot test partners, such as the counties in eastern Ontario that are testing the Infection Watch Live system.
  • the company should forestall any concerns over privacy issues by spelling out how it ensures data on individuals are kept confidential.
  • There's nothing wrong with using the current concerns over H1N1 flu to gain exposure, as long as Infonaut is careful about taking a calm and respectful tone to its marketing and publicity.
  • On the other hand, it will clearly create an opportunity if Infonaut can increase its profile, "which helps it to get its story out, which helps it to get investors, which helps it to grow.
  • The problem Build a market for a unique infection mapping system without appearing to exploit the flu outbreak The plan: Use a subtle approach and be upfront with the state of development of the software products The payoff: Higher awareness among potential customers and an expanded market
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    Using 21st-century Infonaut is using software to create maps - the containment of disease - by showing infection patterns that can be understood at a glance.
Assunta Krehl

reportonbusiness.com: Failure and risk - 0 views

  • Charles Plant, Managing Director of the Market Readiness Program for entrepreneurs at MaRS
  • Plant says that acceptance of failure is a cultural problem in Canada in that we tend not to reward the people who have failed. "We tend to punish people who fail whereas in Silicon Valley, they tend to reward people who have failed because they've learned lessons and can gain from that failure.
  • "I think you have to quickly acknowledge when something is a failure and have a back up plan of what you're going to do," says Plant. "Don't keep flogging a dead horse."
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  • "To make failure a learning experience, first you have to celebrate it by acknowledging in a very positive way, the person who tried something and failed. You can't hide it under a table," says Plant. "You've got to develop a system that both rewards for the attempt as well as the success. Frequently, we don't do that and that sends a bad message. The act of punishing people makes them want to stop innovating."
  • We also need to build more accountability into failure, according to Plant who says that when failures are detrimental to the economy, we can't pretend that nothing happened. "Right now, some people are being rewarded for absolutely hideous failures, such as in the banking system," says Plant, who is also a Chartered Management Accountant. "Part of the problem is accounting which does a very poor job of measuring risk. Never leave anything up to the accountants!"
  • According to Plant, there's a different risk tolerance in smaller companies versus big ones, although he doesn't see a real difference by industry. Whether a company tolerates or accepts risk depends largely on the nature of the company. "The more established companies probably don't tolerate failure as well so they don't actually incubate a culture of risk," says Plant. "Larger companies do a lot of things to make sure they don't fail. Smaller ones tend to favour risk because it's the only way they can get ahead. And if you're doing things that haven't been done before, then you're going to fail again and again."
  • "You have to allow people to fail in this economy," says Plant. "It's failure that leads to productivity gain and innovation."
  • "You need a culture that allows failure for success because without it, people become anti-failure," says Charles Plant. "Trying different things is the act of innovation. If you fail 14 times, hopefully you're going to succeed on the 15th try. Without failure, we're not going to be driving and growing the economy."
  • Innovation is the result of taking big leaps,
  • Innovation is the result of taking big leaps, but failure is often the downside of taking those leaps.
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    without failure, you can't drive productivity. without failure, there is no innovation. So we need to fail to improve the economy!
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    The Globe and Mail investigates the failure and risks with businesses and innovation with business leaders, Tony Chapman, CEO of Capital C, a Toronto communications and advertising company, Charles Plant, Managing Director of the Market Readiness Program for entrepreneurs at MaRS, and Naeem 'Nick' Noorani, founder and publisher of Canadian Immigrant magazine.
Assunta Krehl

Scratching The Biotech Surface - Backbone Magazine - 0 views

  • We don’t know for sure,” said Dr. John Evans, chair of the board of directors at MARS (Medical and Related Sciences) Discovery District in Toronto, and vicechair of Mississauga, Ont.-based NPSAllelix Biopharmaceuticals, one of the pioneers of biotech in Canada. “But we believe that if you could ‘type’ the patient processes of how he/she handles a drug, you could peel off those people who would be particularly sensitive to a drug. Then you could find a sub-population where the drug is safe and highly effective.” Evans used the arthritis drug Vioxx as an example. It helped millions of people battle painful inflammation, but was pulled from the market recently because of potential cardiac side effects in some people. “If the drug company could have predicted which patients would have complications from Vioxx treatment — through some genetic profiling — then a very powerful and effective drug could have been preserved,” Evans said. His company, NPS-Allelix Bio-pharmaceuticals, has been developing a product since 1989 that will be launched later this year. The drug secretes a parathyroid hormone for treating osteoporosis.
  • It builds up bone matrix and helps build bone, rather than just delay bone loss as other drugs do.
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    The field of biotechnology is a collaboration between research disciplines who have a quantitative view of the world. A review of how human genome affects drug development is reviewed.
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    The field of biotechnology is a collaboration between research disciplines who have a quantitative view of the world. A review of how human genome affects drug development is reviewed. Sept 11, 2005
Assunta Krehl

Dr. Calvin Stiller appointed Chair of Board of Directors - Ontario Institute for Cancer... - 0 views

  • The Board of Directors of the Ontario Institute for Cancer Research (OICR) has appointed Dr. Calvin Stiller as the Chair of the Board.
  • He succeeds Dr. John Evans, who was the first Chair and who will continue to serve as a board member.
  • Dr. Stiller co-founded the MaRS Centre in Toronto
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    The Board of Directors of the Ontario Institute for Cancer Research (OICR) has appointed Dr. Calvin Stiller as the Chair of the Board. Mention of Dr. Stiller Co-Founding MaRS.
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    The Board of Directors of the Ontario Institute for Cancer Research (OICR) has appointed Dr. Calvin Stiller as the Chair of the Board. Mention of Dr. Stiller Co-Founding MaRS. Jan 21, 2009
Assunta Krehl

Robarts and WORLDiscoveries go to MaRS - Western News - 0 views

  • The event will mark the official opening of the new WORLDiscoveries office at MaRS.   WORLDiscoveries is a joint business development consortium formed between Western, Robarts and Lawson Health Research Institute to bridge local inventions and global industry.  
  • The MaRS Discovery District is a non-profit innovation centre that connects science, technology and entrepreneurs with business skills, networks and capital to stimulate innovation and accelerate the growth of successful Canadian enterprise
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    John MacDonald, new Director of Robarts Research Institute was at a luncheon at MaRS on March 17 to bring awareness of the leadership role Robarts and The University of Western Ontario, plays in furthering Canada's innovation agenda through the production of leading research. It also mentions about the official opening of WORLDiscoveries office at MaRS.
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    John MacDonald, new Director of Robarts Research Institute was at a luncheon at MaRS on March 17 to bring awareness of the leadership role Robarts and The University of Western Ontario, plays in furthering Canada's innovation agenda through the production of leading research. It also mentions about the official opening of WORLDiscoveries office at MaRS. March 16, 2009
Assunta Krehl

Daily Exchange - 0 views

  • On June 9-11, 2009, the Martin Prosperity Institute, in partnership with the Ontario Ministry of Culture, and the City of Toronto - Economic Development, Culture & Tourism Division, will be hosting the inaugural Placing Creativity Conference at the MaRS Centre, 101 College Street, Toronto, Ontario, Canada.
  • The Conference brings together diverse stakeholders from government, the private sector and the academic world to explore the importance of mapping culture in relation to creative spaces and places.
  • "The mission of Placing Creativity is to advance the understanding and practice of cultural resource mapping by developing reusable maps that showcase the cultural sector in Toronto and that can be shared with other jurisdictions and groups," said Kevin Stolarick, Research Director, The Martin Prosperity Institute.
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  • The conference, featuring international speakers such as Richard Lloyd of Vanderbilt University, will investigate cultural mapping from a number of unique perspectives and disciplines, and will support the interaction of policy-makers, academics and new researchers. Richard is author of "Neo-Bohemia: Art and Commerce in the Postindustrial City". Other Speakers include British-based cultural policy expert Colin Mercer. The conference is an extension of the Placing Creativity partnership which investigates the interconnection between 'Place' and 'Creativity' through a number of different lenses.
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    The Martin Prosperity Institute, in partnership with the Ontario Ministry of Culture, and the City of Toronto - Economic Development, Culture & Tourism Division, will be hosting the inaugural Placing Creativity Conference at MaRS June 9-11, 2009. The conference will look at the interconnection between 'Place' and 'Creativity' through a number of different lenses.
Sarah Hickman

Office of Climate Change, UK - Our activities - Stern Review - 0 views

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    The first half of the Review focuses on the impacts and risks arising from uncontrolled climate change, and on the costs and opportunities associated with action to tackle it. A sound understanding of the economics of risk is critical here. The Review emphasises that economic models over timescales of centuries do not offer precise forecasts - but they are an important way to illustrate the scale of effects we might see. The second half of the Review examines the national and international policy challenges of moving to a low-carbon global economy. Climate change is the greatest market failure the world has seen. Three elements of policy are required for an effective response.
Sarah Hickman

MaRS Discovery District - Recommended Resources - Global Market Reports - VHA Research ... - 0 views

  •  
    "The United States spends more on health care-related research and development than any other country. In 2003, it was estimated that the Federal government alone spent over $26 billion. Pharmaceutical companies, device manufacturers and other private companies invested over $10 billion more. At its best, the American health care system is capable of delivering care unsurpassed anywhere else in the world. Yet, a 1999 Institute of Medicine study estimated that as many as 98,000 Americans die each year from hospital related medical errors. A recent study by the Rand Corporation (a non-profit think tank) concluded that less than 50 percent of encounters with doctors and hospitals resulted in optimal, evidence-based treatment. Studies show that as many as 42 million Americans - almost 15 percent of the population - lack health care insurance. Surveys reveal that patients do not feel they have adequate information about their conditions, and that their experience with health care ranks below that of most other sectors, in fact below that of the post office. In the aggregate, the country is spending nearly $2 trillion on health care, and yet the nation's health care system does not meet acceptable thresholds for safety, quality, access or cost. In 2005, VHA Health Foundation's board of directors sought to better understand the reasons behind this paradox. The foundation commissioned Larry Keeley and his associates at Doblin Inc. to apply the rigorous analytical methods that are used in their evaluation of other American industries and companies. The project set out to discover when, where and how innovation was taking place in health care. It also sought to identify organizations that were developing model innovation processes, and to explore where opportunities for successful innovation might lay."
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